DR.ÖĞR.ÜYESİ ASLI KOÇ    
Adı : ASLI
Soyadı : KOÇ
E-posta : akoc@ankara.edu.tr, aslikoc79@gmail.com
Tel : 0 312 203 30 61
Ünvan : DR.ÖĞR.ÜYESİ
Birim : ECZACILIK FAKÜLTESİ
Bölüm : Ankara Üniversitesi Eczacılık Fakültesi Biyokimya Anabilim Dalı
Kişisel Akademik Bilgiler

KİŞİSEL BİLGİLER

Adı Soyadı: Aslı Koç

Doğum Tarihi: 26.08.1979

Doğum Yeri: Ankara

İletişim Adresi: Ankara Üniversitesi Eczacılık Fakültesi Merkez Laboratuvarı, Tandoğan, Ankara, Türkiye 06100

İş Tel: +90 312 203 30 61                             GSM: +90 505 403 20 96

E-posta: aslikoc79@gmail.com, akoc@ankara.edu.tr


EĞİTİM

DOKTORA

Ankara Üniversitesi Eczacılık Fakültesi Biyokimya Anabilim Dalı 2004-2011

YÜKSEK LİSANS

Gazi Üniversitesi Tıp Fakültesi Tıbbi Biyokimya Anabilim Dalı    2002-2004                      

LİSANS

Hacettepe Üniversitesi Fen Fakültesi Biyoloji Bölümü 1997-2001

LİSE

Ankara Ayrancı Süper Lisesi 1993-1997


AKADEMİK DENEYİM

Witten/Herdecke University, Faculty of Health, Department of Medicine, Institute of Immunology& Experimental Oncology, Center for Biomedical Education and Research

(Ziyaretçi araştırmacı) 2016 (3 ay)

Ankara Üniversitesi Eczacılık Fakültesi Biyokimya Anabilim Dalı  

(Araştırma Görevlisi) 2009-2011


ULUSAL VE ULUSLARARASI HAKEMLİ DERGİLERDEKİ YAYINLAR VE KONGRELERDE SUNULAN BİLDİRİLER

Koc A, Ozkan T, Karabay AZ, Sunguroglu A, Aktan F. Effect of L-carnitine on the synthesis of nitric oxide in RAW 264·7 murine macrophage cell line. Cell Biochem. Funct., 9(8):679-85, 2011.

Karabay AZ, Koc A, Gurkan S,  Buyukbingol Z, Buyukbingol E. Inhibitory effects of indole α-lipoic acid derivatives on nitric oxide production in LPS/IFN-γ activated RAW 264.7 macrophages. Cell Biochem Funct., 33(3): 121-7, 2015.

Arzu Zeynep Karabay, Asli Koc, Tulin Ozkan, Yalda Hekmatshoar, Asuman Sunguroglu, Fugen Aktan, Zeliha Buyukbingol. Methylsulfonylmethane induces p53 independent apoptosis in HCT-116 colon cancer cells. International Journal of Molecular Sciences, 17(7):1123, 2016.

Koç A, Ozkan T, Karabay AZ, Hekmatshoar Y, Gurkan-Alp AS, Aktan F, Buyukbingol Z, Sunguroglu A, Buyukbingol E. Apoptotic effects of some tetrahydronaphthalene derivatives on K562 human chronic myelogenous leukemia cell line. Anticancer Agents Med Chem. 2017 Apr 12. doi: 10.2174/1871521409666170412122811. 

Arzu Zeynep Karabay, Aslı Koç, Tülin Özkan, Asuman Sunguroglu, Fügen Aktan, Zeliha Büyükbingöl. Effects of glucosamine on LPS/IFN-γ induced RAW 264.7 macrophage apoptosis. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 65(1):11-18, 2012.

Arzu Z. Karabay, Aslı Koç, Tülin Özkan, Zeliha Büyükbingöl, Asuman Sunguroğlu, Fügen Aktan. Effect of Taurine on Hydrogen Peroxide Production in Lipopolysaccharide Induced RAW 264.7 Macrophage Cells. FABAD J. Pharm. Sci, 33:187-192, 2008.

Aslı Koç, Arzu Zeynep Karabay, Tülin Özkan, Zeliha Büyükbingöl, Asuman Sunguroğlu, Fügen Aktan. L-Karnitin ve Alfa-lipoik asitin HCT 116 +/+ ve -/- kolon kanser hücre serilerinin proliferasyonu üzerindeki sinerjetik etkileri. Ankara Sağlık Hizmetleri Dergisi, 15(2):1-7, 2016.

Aktan, F., Karabay, A.Z., Koc, A. Synergetic effects of L-Carnitine and α-lipoic acid on viability of HCT 116 cell line. 12th Annual World Congress Insulin Resistance, Diabetes and Cardiovascular Disease (WCIRDC), 20-22 Kasım, 2014, Los Angeles, CA, Amerika Birleşik Devletleri.

Arzu Z. Karabay, Asli Koc, Selen Gurkan, Zeliha Buyukbingol, Erdem Buyukbingol. Effects of indole α-lipoic acid derivatives on nitric oxide production in LPS/IFN-γ activated RAW 264.7 macrophages.  FEBS/EMBO 2014 Conference, 30 Ağustos- 4 Eylül 2014, Paris, Fransa.

A.Z. Karabay, A. Koc, T. Ozkan, Z. Buyukbingol, A. Sunguroglu, Fugen Aktan. Effect of imatinib on nitrite levels in LPS/IFNγ activated RAW 264.7 macrophages. LIPID MAPS Annual Meeting 2014: Lipidomics Impact on Cell Biology, Inflammation and Metabolic Disease, 13-14 Mayıs 2014, La Jolla, CA, Amerika Birleşik Devletleri.

Fugen Aktan, Asli Koc. L-Carnitine effects nitric oxide production in RAW 264.7 macrophage cells after LPS stimulation. LIPID MAPS Annual Meeting 2013: Impact of Lipidomics on Oxidized Lipids and Non-Alcoholic Fatty Liver Disease, 7-8 Mayıs 2013, La Jolla, CA, Amerika Birleşik Devletleri.

A. Koc, A.Z. Karabay, T. Ozkan, B. Altınok, Z. Buyukbingol, A. Sunguroglu, F. Aktan. Differences between akirin protein levels in imatinib resistant and sensitive K562 cell lines, International symposium of the German Society for Biochemistry and Molecular Biology, 3-6 Ekim 2013, Frankfurt, Almanya.

Arzu Z. Karabay, Aslı Koc, Tulin Ozkan, Asuman Sunguroglu, Zeliha Buyukbingol, Fugen Aktan. Examination of common gene targets for β-catenin and NFkB proteins in imatinib sensitive and resistant K562 cell lines. Analysis of autophagy regulation: Discussion of recent research and new technologies meeting. 3 Ekim 2013, Londra, İngiltere.

Asli Koc, Tulin Ozkan, Arzu Z. Karabay, Asuman Sunguroglu, Zeliha Buyukbingol, Fugen Aktan. Interaction of NFkB and akirin proteins in imatinib resistant and sensitive K562 cell lines. Analysis of autophagy regulation: Discussion of recent research and new technologies meeting. 3 Ekim 2013, Londra, İngiltere.

A.Z. Karabay,  T. Ozkan,  A. Koc, A. Sunguroglu, Z. Buyukbingol. Effects of methylsulfonylmethane on viability of HCT-116 cell line.  22. IUBMB/37. FEBS Kongresi, 4-9 Eylül 2012, Sevilla, İspanya.

Ozkan T, Koc A, Karabay A Z, Sunguroglu A, Buyukbingol Z, Aktan F. Different expression pattern of akirin-2 in K562r and K562s cell lines. EMBO Conference Series. Intracellular RNA localization and localized translation, 7-12 Ağustos 2011, Barga, İtalya.

Karabay A Z, Ozkan T, Koc A, Sunguroglu A, Aktan F, Büyükbingol Z. Effect of carnosine on nitrite production in LPS-activated RAW 264.7 macrophages. EMBO Conference Series. Intracellular RNA localization and localized translation, 7-12 Ağustos 2011, Barga, İtalya.

Aktan F, Koc A, Karabay A. Effects of L-carnitine in SNP induced RAW 264.7 macrophages. Human Proteome World Congress HUPO 2010, 19-23 Eylül 2010, Sidney, Avusturalya.

A. Koc, T. Ozkan,  Z. Karabay A., A. Sunguroglu, F. Aktan. Effect of L-Carnitine on NF-kB Activity in lipopolysaccharide stimulated RAW 264.7 macrophage cell line. 35. FEBS Kongresi, 26 Haziran-1 Temmuz 2010, Göteborg, İsveç.

T. Ozkan, A. Karadag, B. Altinok, A.Z. Karabay, A. Koc, S. Bozkurt, S. Aydos, A. Sunguroglu. NF-kappaB activation and complex control of NOS2 gene promoter in K562 imatinib mesylate resistant CML cell line. 35. FEBS Kongresi, 26 Haziran-1 Temmuz 2010, Göteborg, İsveç.

A.Z. Karabay, T. Ozkan, A. Koc, A. Sunguroglu, Z. Buyukbingol. Effect of methylsulfonylmethane on LPS-IFN-gamma induced RAW 264.7 macrophage apoptosis. 35. FEBS Kongresi, 26 Haziran-1 Temmuz 2010, Göteborg, İsveç.

A.Z. Karabay, T. Ozkan, A. Koc, A. Karadag, B. Altinok, Z. Buyukbingol, A. Sunguroglu. Effect of wnt3a or lithium chloride preconditioning on nitric oxide production in RAW 264.7 macrophages and K562 leukemic cell line. 35. FEBS Kongresi, 26 Haziran-1 Temmuz 2010, Göteborg, İsveç.

Koc A., Aktan F. Effect of Poloxamer 407 on Nitric Oxide Production and Cell Viability in LPS Induced RAW 264.7 Macrophage Cell Line. 8. Annual World Congress on Insulin Resistance, Diabetes and Cardiovascular Disease, 4-6 Kasım 2010, Los Angeles, CA, Amerika Birleşik Devletleri.

T. Ozkan, T, ZA Karabay, A Koç, A Karadag, S Aydos, E Çalıskan, G Özturk, SN Ilgaz, I Yükselen, A Sunguroglu. Wheatgrass extract increases proliferation of RAW 264.7 macrophages induced by hydrogen peroxide (H2O2) or lipopolysaccharide (LPS). 57th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural  Product Research, 16-20 Ağustos, 2009, Cenevre, İsviçre.

A.Z.  Karabay, T Özkan, A Koç, Z Büyükbingöl, A Sunguroglu. Effects of MSM (methylsulfonylmethane) on SNP (sodium nitroprusside) and H2O2 (hydrogen peroxide) induced RAW 264.7 macrophages. 57th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural  Product Research, 16-20 Ağustos, 2009, Cenevre, İsviçre.

A. Z. Karabay, A. Akinci, T. Özkan, A. Sunguroglu, F. Aktan, Z. Buyukbingol. Effect of methylsulfonylmethane on proliferation and nitric oxide production in LPS activated RAW 264.7 cells. 34. FEBS Kongresi. Life’s Molecular Interactions. 4 – 9 Temmuz 2009, Prag, Çek Cumhuriyeti.

A. Akinci, A. Karabay, T. Özkan, A. Sunguroglu, F. Aktan. The effect of LPS incubation periods on nitric oxide levels in RAW 264.7 macrophage cell line. 34. FEBS Kongresi. Life’s Molecular Interactions. 4 – 9 Temmuz 2009, Prag, Çek Cumhuriyeti.

T. Ozkan, F. Bakar, A. Z. Karabay, A. Akinci, B. Altinok, A. Karadag, S. Aydos, A. Sunguroglu. Wheatgrass extract effects lipid peroxidation levels in human promyelocytic leukemia cell line HL-60.  34. FEBS Kongresi. Life’s Molecular Interactions. 4 – 9 Temmuz 2009, Prag, Çek Cumhuriyeti.

Asli Koc, Arzu Z. Karabay, Tulin Ozkan, Aynur Karadag, Asuman Sunguroglu, Fugen Aktan, Zeliha Buyukbingol. Effect of L-carnitine on NO production in lipopolysaccharide induced RAW 264.7 cells. III. International Congress of Molecular Medicine 5–8 Mayıs 2009, İstanbul, Türkiye.

Sena Aydos, Tulin Ozkan, Arzu Z. Karabay, Asli Koc, Aynur Karadag, Buket Altinok, Asuman Sunguroglu. Wheatgrass juice reduces nitric oxide production in LPS induced raw 264.7 cells. III. International Congress of Molecular Medicine 5–8 Mayıs 2009, İstanbul, Türkiye.

Koç Aslı, Karabay Arzu Zeynep, Özkan Tülin, Gürkan Alp Ayşe Selen, Aktan Fügen, Büyükbingöl Zeliha, Büyükbingöl Erdem. Retinoid Analoglarının Kronik Miyeloid Lösemi K562 Hücrelerindeki Apoptotik Etkileri. 23. Ulusal Biyoloji Kongresi 5-9 Eylül 2016, Gaziantep, Türkiye. 

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