PROF.DR. ABDURRAHMAN MİTHAT BOZDAYI    
Adı : ABDURRAHMAN MİTHAT
Soyadı : BOZDAYI
E-posta : bozdayi@ankara.edu.tr
Tel : 3620566
Ünvan : PROF.DR.
Birim : HEPATOLOJİ ENSTİTÜSÜ
Bölüm : Hepatoloji Enstitüsü
Kişisel Akademik Bilgiler

 

ÖZGEÇMİŞ

Adı: A. Mithat

Soyadı: Bozdayı

E-Posta: bozdayi@ankara.edu.tr

Tel: 90-312-362 05 66

Ünvan: Profesör Doktor

Birim: Tıp Fakültesi

Bölüm: Hepatoloji Enstitüsü

 

Eğitim Durumu

 

Lisans (1980-1983)                   İstanbul Üniversitesi, İstanbul Tıp Fakültesi

Lisans (1983-1984)                     Gülhane Askeri Tıp Akademisi, Gülhane Tıp Fakültesi

Lisans (1984-1987)                   İstanbul Üniversitesi, Cerrahpaşa Tıp Fakültesi

İhtisas (1989-1993)                     Biyokimya ve Klinik Biyokimya,  Türkiye Yüksek İhtisas Hastanesi

Doktora (1993-1996)      Biyoloji Bölümü, Orta Doğu Teknik Üniversitesi

            Doçentlik (1996-2003)    Biyokimya ve Klinik Biyokimya

                                                                                                         

      I.        Çalıştığı Kurum ve Görevi

 

Enstitü Müdür yardımcısı (2002- )       Ankara Üniversitesi Hepatoloji Enstitüsü              

    II.        Yurtdışı Yayınlar

 

1.     Katircioglu, S.F., Kucukaksu, D.S., Bozdayi, M., Saydam, G., Zorlutuna, I.Y., Tasdemir, O., Bayazit, K. Effects of prostacyclin on heparin reversal with protamine (1992) Vascular Surgery, 26  464-473.

2.   Kucukaksu, D.S., Katircioglu, S.F., Saydam, G., Bozdayi, M., Mavitas, B., Tasdemir, O., Bayazit, K. Beneficial effects of prostacyclin on pulmonary function during heparin reversal with protamine (1993) Vascular Surgery, 27 264-267.

3.   Katircioglu, S.F., Küçükaksu, D.S., Bozdayi, M., Dalva, K., Mavitaş, B., Zorlutuna, Y., Taşdemir, O., Bayazit, K. The beneficial effects of aminophylline administration on heparin reversal with protamine (1994) Surgery Today, 24  99-102.

4.   Katircioǧlu, S.F., Küçükaksu, D.S., Bozdayi, M., Taşdemir, 0., Bayazit, K. Beneficial effects of prostacyclin treatment on reperfusion of the myocardium. (1995) Cardiovascular Surgery, 3 405-408.

5.   Bozdayi, M., Borowiec, J., Nilsson, L., Venge, P., Thelin, S., Hansson, H.E. Effects of heparin coating of cardiopulmonary bypass circuits on in vitro oxygen free radical production during coronary bypass surgery (1996) Artificial Organs, 20 1008-1016

6.   Bozkaya, H., Bozdayi, M., Uzunalimoglu, O., Cetinkaya, H., Yurdaydin, C., Karayalcin, S., Sf Lok, A. Relationship between mutations in the pre-core/core promoter region and HBe antigen status in patients with chronic HBV infection (1997) Turkish Journal of Gastroenterology, 8 277-282.

7.   Borowiec, J.W., Bozdayi, M., Jaramillo, A., Nilsson, L., Venge, P., Henze, A. Influence of two blood conservation techniques (Cardiotomy reservoir versus cell-saver) on biocompatibility of the heparin coated cardiopulmonary bypass circuit during coronary revascularization surgery (1997) Journal of Cardiac Surgery, 12 190-197.

8.   Uzunalimoglu, O., Bozkaya, H., Cetinkaya, H., Bozdayi, A.M., Yurdaydin, C., Erdi, H., Gurler, A., Cagsin, S., Karayalcin, S. Is there any relationship between Behcet's disease and hepatitis C virus? (1998) Turkish Journal of Gastroenterology, 9  10-13.

9.   Boran, M., Bozdayi, M., Cetin, S. Arachidonic acid metabolites as biocompatibility parameters for cellulosic membranes. (1999) Nephrology Dialysis Transplantation, 14 1804-1805.

10.  Akbay, A., Çinar, K., Uzunalimoǧlu, Ö., Eranil, S., Yurdaydin, C., Bozkaya, H., Bozdayi, M. Serum cytotoxin and oxidant stress markers in N-acetylcysteine treated thioacetamide hepatotoxicity of rats (1999) Human and Experimental Toxicology, 18 669-676.

11.  Bozdayi, A.M., Bozkaya, H., Türkyilmaz, A., Aslan, N., Verdi, H., Kence, A., Uzunalimoglu, Ö. Polymorphism of precore region of hepatitis B virus DNA among patients with chronic HBV infection in Turkey (1999) Infection, 27 357-360.

12.  Idilman, R., Ustun, C., Aslan, O., Ozcan, M., Arat, M., Bozkaya, H., Bozdayi, M., Sengezer, T., Uzunalimoglu, O., Dokmeci, A., Ilhan, O., Koc, H., Akan, H. The incidence of Hepatitis G virus in patients with hematological malignancies: The relationship to the number of blood and blood products transfusions (2000) Turkish Journal of Haematology, 17 67-71.

13.  Bozdayi, A.M., Uzunalimoglu, O., Aslan, N., Bozkaya, H., Türkyilmaz, A.R., Kayhan, B., Sahin, T., Sivri, B., Uygun, A., Altiok, A., Çetinkaya, H., Karayalçin, S., Yurdaydin, C. Influence of viral load and alanine aminotransferase on viral genetic heterogeneity in patients with chronic hepatitis C virus infection (2000) Intervirology, 43  61-66.

14.  Arican, A., Sengezer, T., Bozdayi, M., Bozkaya, H., Üçgül, E., Dinçol, D., Uzunalimoǧlu, O. Prevalence of hepatitis-G virus and hepatitis-C virus infection in patients with non-Hodgkin's lymphoma (2000) Medical Oncology, 17 123-126.

15.  Bozkaya, H., Bozdayi, A.M., Aslan, N., Türkay, C., Sarioglu, M., Çetinkaya, H., Akdogan, M., Cinar, K., Erden, E., Köse, K., Sentürk, H., Akkiz, H., Karayalcin, S., Yurdaydin, C., Uzunalimoglu, Ö. Circulating IL-2 and IL-10 in chronic active hepatitis C with respect to the response to IFN treatment (2000) Infection, 28  309-313.

16.  Bozkaya, H., Bozdayi, M., Turkyilmaz, R., Sarioglu, M., Cetinkaya, H., Cinar, K., Kose, K., Yurdaydin, C., Uzunalimoglu, O. Circulating IL-2, IL-10 and TNF-α in chronic hepatitis B: Their relations to HBeAg status and the activity of liver disease (2000) Hepato-Gastroenterology, 47 1675-1679.

17.  Bozdayi, A.M., Bozkaya, H., Türkyilmaz, A.R., Sarıoglu, M., Çetinkaya, H., Karayalçin, S., Yurdaydin, C., Uzunalimoǧlu, Ö. Nucleotide divergences in the core promoter and precore region of genotype D hepatitis B virus in patients with persistently elevated or normal ALT levels (2001) Journal of Clinical Virology, 21 91-101.

18.  Idilman, R., Çetinkaya, H., Sava, S., Aslan, N., Sak, S.D., Batemir, M., Sariolu, M., Soykan, R., Bozdayı, M., Colantoni, A., Aydntu, O., Bahar, K., Uzunalimolu, O., Van Thiel, D.H., Numanolu, N., Dökmeci, A. Bronchoalveolar lavage fluid analysis in individuals with chronic hepatitis C (2002) Journal of Medical Virology, 66 34-39.

19.  Yurdaydin, C., Bozkaya, H., Gürel, S., Tillmann, H.L., Aslan, N., Okçu-Heper, A., Erden, E., Yalçin, K., Iliman, N., Uzunalmoǧlu, O., Manns, M.P., Bozdayi, A. Mithat Famciclovir treatment of chronic delta hepatitis (2002) Journal of Hepatology, 37 266-271.

20.  Bozkaya, H., Yurdaydin, C., Törüner, M., Arat, M., Bozdayi, A.M., Erekul, S., Çinar, K., Koç, H., Uzunalimoǧlu, Ö. Remission of severe aplastic anemia associated with hepatitis B virus infection after viral clearance: Potential role of lamivudine (2002) Digestive Diseases and Sciences, 47 1782-1785.

21.  Bozkaya, H., Yurdaydin, C., Bozdayi, A.M., Erkan, O., Karayalcin, S., Uzunalimoglu, O. Oral ganciclovir for treatment of lamivudine-resistant hepatitis B virus infection: A pilot study (2002) Clinical Infectious Diseases, 35 960-965.

22.  Senturk, H., Ersoz, G., Ozaras, R., Kaymakoglu, S., Bozkaya, H., Akdogan, M., Mert, A., Bozdayi, M., Tabak, F., Yenice, N., Ozbay, G. Interferon-α2b induction treatment with or without ribavirin in chronic hepatitis C: A multicenter, randomized, controlled trial (2003) Digestive Diseases and Sciences, 48 1124-1129.

23.  Yalcin, K., Degertekin, H., Yurdaydin, C., Bozdayi, M., Bozkaya, H. The role of HBeAG eroconversion in acute exacerbation of liver disease with termination of hepatitis B and D virus infection in a chronic hepatitis D patient during α-interferon therapy (2003) European Journal of Gastroenterology and Hepatology, 15 819-823.

24.  Bozdayi, A.M., Uzunalimoǧlu, Ö., Türkyilmaz, A.R., Aslan, N., Sezgin, O., Sahin, T., Bozdayi, G., Çinar, K., Pai, S.B., Pai, R., Bozkaya, H., Karayalçin, S., Yurdaydin, C., Schinazi, R.F. YSDD: A novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine (2003) Journal of Viral Hepatitis, 10 256-265.

25.  Barut, G., Balci, H., Bozdayi, M., Hatemi, I., Ozcelik, D., Senturk, H. Screening for iron overload in the Turkish population (2003) Digestive Diseases, 21 279-285.

26.  Idilman, R., Arat, M., Soydan, E., Törüner, M., Soykan, I., Akbulut, H., Arslan, Ö., Özcan, M., Türkyilmaz, A.R., Bozdayi, M., Karayalçin, S., Van Thiel, D.H., Özden, A., Beksaç, M., Akan, H.Lamivudine prophylaxis for prevention of chemotherapy-induced hepatitis B virus reactivation in hepatitis B virus carriers with malignancies (2004) Journal of Viral Hepatitis, 11 141-147.

27.  Aslan, N., Bozdayi, A.M., Çetinkaya, H., Sarioǧlu, M., Türkay, C., Bozkaya, H., Karayalçin, S., Yurdaydin, C., Uzunalimoǧlu, Ö. The mutations in ISDR of NS5A gene are not associated with response to interferon treatment in Turkish patients with chronic hepatitis C virus genotype 1b infection (2004) Turkish Journal of Gastroenterology, 15 21-26.

28.  Bozkaya, H., Bektas, M., Metin, O., Erkan, O., Ibrahimoglu, D., Dalva, K., Akbiyik, F., Gurel, S., Bozdayi, A.M., Akay, C., Yurdaydin, C., Aslan, O., Uzunalimoglu, O. Screening for hemochromatosis in Turkey (2004) Digestive Diseases and Sciences, 49 (3), pp. 444-449.

29.  Yalcin, K., Degertekin, H., Bozdayi, M. Late Failure of Combined Recombinant Hepatitis B Vaccine and Lamivudine in Treatment of a Patient with Chronic Hepatitis B (2004) Southern Medical Journal, 97 407-409.

30.  Bozdayi, A.M., Eyigun, C.P., Turkyilmaz, A.R., Avci, I.Y., Pahsa, A., Yurdaydin, C. A novel pattern (sW195a) in surface gene of HBV DNA due to YSDD (L180M plus M204S) mutation selected during lamivudine therapy and successful treatment with adefovir dipivoxil (2004) Journal of Clinical Virology, 31 76-77.

31.  Karavelioǧlu, D., Koytak, E.S., Bozkaya, H., Uzunalimoǧlu, Ö., Bozdayi, A.M., Yurdaydin, C. Lichen planus and HCV infection in Turkish patients (2004) Turkish Journal of Gastroenterology, 15 133-136.

32.  Bozdayi, A.M., Aslan, N., Bozdayi, G., Türkyilmaz, A.R., Sengezer, T., Wend, U., Erkan, Ö., Aydemir, F., Zakirhodjaev, S., Orucov, Ş., Bozkaya, H., Gerlich, W., Karayalçin, S., Yurdaydin, C., Uzunalimoǧlu, Ö. Molecular epidemiology of hepatitis B, C and D viruses in Turkish patients (2004) Archives of Virology, 149  2115-2129.

33.  Törüner, M., Erkan, Ö., Soykan, I., Bozdayi, M., Çetinkaya, H., Yurdaydin, C., Uzunalimoǧlu, Ö., Özden, A. Factor V Leiden, prothrombin G20210A and MTHFR gene mutations in inflammatory bowel disease (2004) Turkish Journal of Gastroenterology, 15 250-252.

34.  Erkan, O., Bozdayi, A.M., Disibeyaz, S., Oguz, D., Ozcan, M., Bahar, K., Karayalcin, S., Ozden, A., Bozkaya, H., Yurdaydin, C., Uzunalimoglu, O. Thrombophilic gene mutations in cirrhotic patients with portal vein thrombosis (2005) European Journal of Gastroenterology and Hepatology, 17 339-343.

35.  Çelik, T., Gören, M.Z., Çmar, K., Gürdal, H., Önder, F.O., Tan, A., Terzioǧlu, B., Bozdayi, A.M., Bozkaya, H., Uzunalimoǧlu, Ö., Yurdaydin, C. Fatigue of cholestasis and the serotoninergic neurotransmitter system in the rat (2005) Hepatology, 41 731-737.

36.  Yurdaydin, C., Bozkaya, H., Çetinkaya, H., Şahin, T., Karaoǧuz, D., Törüner, M., Erkan, Ö., Heper, A.O., Erden, E., Bozdayi, A.M., Uzunalimoǧlu, Ö. Lamivudine vs lamivudine and interferon combination treatment of HBeAg (-) chronic hepatitis B (2005) Journal of Viral Hepatitis, 12 262-268.

37.  Pai, S.B., Bozdayi, A.M., Pai, R.B., Beker, T., Sarioglu, M., Turkyilmaz, A.R., Grier, J., Yurdaydin, C., Schinazi, R.F. Emergence of a novel mutation in the FLLA region of hepatitis B virus during lamivudine therapy (2005) Antimicrobial Agents and Chemotherapy, 49 2618-2624.

38.  Bozdayi, G., Türkyilmaz, A.R., Idilman, R., Karatayli, E., Rota, S., Yurdaydin, C., Bozdayi, A.M. Complete genome sequence and phylogenetic analysis of hepatitis B virus isolated from Turkish patients with chronic HBV infection (2005) Journal of Medical Virology, 76 476-481.

39.  Bozkaya, H., Yurdaydin, C., Idilman, R., Tüzün, A., Cinar, K., Erkan, Ö., Bozdayi, A.M., Erden, E., Uzun, Y., Cetinkaya, H., Uzunalimoglu, Ö. Lamivudine treatment in HBeAg-negative chronic hepatitis B patients with low level viraemia (2005) Antiviral Therapy, 10 319-325.

40.  Idilman, R., Erden, E., Arat, M., Soydan, E., Erkan, O., Kuzu, I., Sahin, Y., Coban, S., Bozdayi, M., Giraud, A., Akan, H., Karayalcin, S., Ozden, A. Trefoil factor expression in biliary epithelium of graft-versus-host disease of the liver after allogeneic hematoietic cell transplantation (2005) Transplantation, 80 1099-1104.

41.  Verdi, H., Koytak, E.S., Önder, O., Ergül, A.A., Cinar, K., Idilman, R., Erden, E., Bozdayi, A.M., Yurdayďin, C., Uzunalimoglu, Ö., Bozkaya, H. Peroxisome proliferator-activated receptor α L162V polymorphism in nonalcoholic steatohepatitis and genotype 1 hepatitis C virus-related liver steatosis (2005) Journal of Investigative Medicine, 53 353-359.

42.  Özdemir, F.T., Duman, D., Ertem, D., Avşar, E., Eren, F., Özdoǧan, O., Kalayci, C., Aslan, N., Bozdayi, A.M., Tözün, N. Determination of hepatitis B genotypes in patients with chronic hepatitis B virus infection in Turkey (2005) Turkish Journal of Gastroenterology, 16 183-187.

43.  Baglan, P.H., Sarinay, E., Ahmed, K., Ozkan, M., Bozday, G., Bozdayı, A.M., Ozden, A. Turkish isolates of Helicobacter pylori belong to the Middle Eastern genotypes (2006) Clinical Microbiology and Infection, 12 97-98.

44.  Kutlu, T., Soycan, L.Y., Karatayli, E., Türkyilmaz, A.R., Yurdaydin, C., Bozdayi, A.M. The first identified hepatitis B virus vaccine escape mutation in Turkey (2006) Journal of Clinical Virology, 35 201-202.

45.  Akay, B.N., Ekmekci, P., Sanli, H., Celik, G., Bozdayi, M. Cutaneous, pulmonary and hepatic sarcoidosis associated with autoimmune complications during interferon-alpha treatment for hepatitis C virus infection (2006) Journal of the European Academy of Dermatology and Venereology, 20 442-445.

46.  Özen, S.C., Daǧli, Ü., Kiliç, M.Y., Törüner, M., Çelik, Y., Özkan, M., Soykan, I., Çetinkaya, H., Ülker, A., Özden, A., Bozdayi, A.M. NOD2/CARD15, NOD1/CARD4, and ICAM-1 gene polymorphisms in Turkish patients with inflammatory bowel disease (2006) Journal of Gastroenterology, 41 304-310.

47.  Çelik, Y., Daǧli, Ü., Kiliç, M.Y., Törüner, M., Özen, S.C., Özkan, M., Soykan, I., Çetinkaya, H., Ülker, A., Özden, A., Bozdayi, A.M. Cytokine gene polymorphisms in Turkish patients with inflammatory bowel disease (2006) Scandinavian Journal of Gastroenterology, 41 559-565.

48.  Aslan, N., Yurdaydin, C., Wiegand, J., Greten, T., Ciner, A., Meyer, M.F., Heiken, H., Kuhlmann, B., Kaiser, T., Bozkaya, H., Tillmann, H.L., Bozdayi, A.M., Manns, M.P., Wedemeyer, H. Cytotoxic CD4+ T cells in viral hepatitis (2006) Journal of Viral Hepatitis, 13  505-514.

49.  Baglan, P.H., Bozdayi, G., Ozkan, M., Ahmed, K., Bozdayi, A.M., Ozden, A. Clarithromycin resistance prevalence and Icea gene status in Helicobacter pylori clinical isolates in Turkish patients with duodenal ulcer and functional dyspepsia (2006) Journal of Microbiology, 44 409-416.

50.  Çabuk, F., Karabulut, H.G., Tuncali, T., Karademir, S., Bozdayi, M., Tükün, A. TBX1 gene mutation screening in patients with non-syndromic Fallot tetralogy (2007) Turkish Journal of Pediatrics, 49  61-68.

51.  Kayhan, H., Karatayli, E., Turkyilmaz, A.R., Sahin, F., Yurdaydin, C., Bozdayi, A.M. Inhibition of hepatitis B virus replication by shRNAs in stably HBV expressed HEPG2 2.2.15 cell lines (2007) Archives of Virology, 152 871-879.

52.  Tasci, I., Mas, M.R., Vural, S.A., Deveci, S., Comert, B., Alcigir, G., Mas, N., Akay, C., Bozdayi, M., Yurdaydin, C., Bozkaya, H., Uzunalimoglu, O., Isik, A.T., Said, H.M. Pegylated interferon-alpha plus taurine in treatment of rat liver fibrosis (2007) World Journal of Gastroenterology, 13  3237-3244.

53.  Karatayli, E., Karayalçin, S., Karaaslan, H., Kayhan, H., Türkyilmaz, A.R., Sahin, F., Yurdaydin, C., Bozdayi, A.M. A novel mutation pattern emerging during lamivudine treatment shows cross-resistance to adefovir dipivoxil treatment (2007) Antiviral Therapy, 12 761-768.

54.  Yurdaydin, C., Bozkaya, H., Karaaslan, H., Önder, F.O., Erkan, Ö.E., Yalçin, K., Deǧertekin, H., Bozdayi, A.M., Uzunalimoǧlu, Ö. A pilot study of 2 years of interferon treatment in patients with chronic delta hepatitis (2007) Journal of Viral Hepatitis, 14 812-816.

55.  Hişmioǧullari, A.A., Bozdayi, A.M., Rahman, K.  Biliary lipid secretion (2007) Turkish Journal of Gastroenterology, 18  65-70.

56.  Ölgen, S., Altanlar, N., Karatayli, E., Bozdayi, M. Antimicrobial and antiviral screening of novel indole carboxamide and propanamide derivatives (2008) Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 63 (3-4), pp. 189-195.

57.  Yurdaydin, C., Bozkaya, H., Önder, F.O., Şentürk, H., Karaaslan, H., Akdoǧan, M., Çetinkaya, H., Erden, E., Erkan-Esin, Ö., Yalçin, K., Bozdayi, A.M., Schinazi, R.F., Gerin, J.L., Uzunalimoǧlu, Ö., Özden, A. Treatment of chronic delta hepatitis with lamivudine vs lamivudine + interferon vs interferon (2008) Journal of Viral Hepatitis, 15 314-321.

58.  Sapmaz, A., Özen Karatayli, S.C., Daǧli, Ü., Kiliç, Z.M.Y., Törüner, M., Çelik, Y., Özkan, M., Soykan, I., Çetinkaya, H., Ülker, A., Özden, A., Bozdayi, A.M. Effects of polymorphism in G2677T/A triallelic region of MDR1 gene in Turkish patients with inflammatory bowel disease (2008) Turkish Journal of Gastroenterology, 19 168-173.

59.  Idilman, R., Kaymakoglu, S., Oguz Onder, F., Ahishali, E., Bektas, M., Cinar, K., Pinarbasi, B., Karayalcin, S., Badur, S., Cakaloglu, Y., Mithat Bozdayi, A., Bozkaya, H., Ökten, A., Yurdaydin, C.  A short course of add-on adefovir dipivoxil treatment in lamivudine-resistant chronic hepatitis B patients (2009) Journal of Viral Hepatitis, 16 279-285.

60.  Yurdaydin, C., Idilman, R., Bozkaya, H., Bozdayi, A.M. Natural history and treatment of chronic delta hepatitis. (2010) Journal of viral hepatitis, 17 749-756.

61.  Sayan, M., Akhan, S.C., Bozdayi, M. Genotype A2/adw2 strain of hepatitis B virus in Turkey: A case report (2010) Hepatitis Monthly, 10  302-305.

62.  Seven, G., Karatayli, S.C., Köse, S.K., Yakut, M., Kabaçam, G., Törüner, M., Okçu Heper, A., Voelker, M., Erden, E., Bozdayi, A.M., Uzunalimoǧlu, Ö., Bozkaya, H., Yurdaydin, C., Schuppan, D. Serum connective tissue markers as predictors of advanced fibrosis in patients with chronic hepatitis B and D (2011) Turkish Journal of Gastroenterology, 22 305-314.

63.  Çelik, I., Karatayli, E., Çevik, E., Gökçe Kabakçi, S., Karatayli, S.C., Dinç, B., Çinar, K., Yalçin, K., Idilman, R., Yurdaydin, C., Bozdayi, A.M. Complete genome sequences and phylogenetic analysis of hepatitis delta viruses isolated from nine Turkish patients (2011) Archives of Virology, 156 2215-2220.

64.  Barlak, Y., Deǧer, O., Çolak, M., Karatayli, S.C., Bozdayi, A.M., Yücesan, F. Effect of Turkish propolis extracts on proteome of prostate cancer cell line (2011) Proteome Science, 9, art no 74

65.  Toy, M., Önder, F.O., Wörmann, T., Bozdayi, A.M., Schalm, S.W., Borsboom, G.J., van Rosmalen, J., Richardus, J.H., Yurdaydin, C. Age- and region-specific hepatitis B prevalence in Turkey estimated using generalized linear mixed models: A systematic review. (2011) BMC Infectious Diseases, 11, art no 337.

66.  Karatayli, S.C., Alagöz, S.G., Mizrak, D., Sayki, M., Özkan, M., Savaş, B., Erden, E., Çinar, K., Idilman, R., Yurdaydin, C., Bozdayi, A.M. Potential proteomic biomarkers in assessing liver fibrosis using SELDI-TOF MS (2012) Turkish Journal of Gastroenterology, 23 46-53.

67.  Karatayli, E., Karatayli, S.C., Cinar, K., Gokahmetoglu, S., Güven, K., Idilman, R., Yurdaydin, C., Bozdayi, A.M. Molecular characterization of a novel entecavir mutation pattern isolated from a multi-drug refractory patient with chronic hepatitis B infection (2012) Journal of Clinical Virology, 53 130-134.

68.  Idilman, R., Cinar, K., Seven, G., Bozkus, Y., Elhan, A., Bozdayi, M., Yurdaydin, C., Bahar, K. Hepatitis B surface antigen seroconversion is associated with favourable long-term clinical outcomes during lamivudine treatment in HBeAg-negative chronic hepatitis B patients (2012) Journal of Viral Hepatitis, 19 220-226.

69.  Yurdakul, A.S., Sönmez, O., Şimşek, C., Zengin, N., Keyf, A.I., Öztürk, C., Öksüzoǧlu, O.B., Kubilay, D., Gülbahar, O.Z., Özen Karatayli, S.C., Bozdayi, A.M. Evaluation of relationship between serum protein profiles and lung cancer by SELDI-TOF-MS (surface enhanced laser desabsorbtion ionization time of flight mass spectrometry) method (2012) Turkiye Klinikleri Journal of Medical Sciences, 32  1084-1089.

70.  Hismiogullari, A.A., Bozdayi, M., Erkan, O., Sel, T., Rahman, K. Isolation of biliary lipid carrying vesicles, analysis of their biochemical properties and hepatic ABCG5 mRNA expression in diosgenin-fed rats (2012) Turkish Journal of Biochemistry, 37 167-174.

71.  Kabaçam, G., Önder, F.O., Yakut, M., Seven, G., Karatayli, S.C., Karatayli, E., Savaş, B., Idilman, R., Bozdayi, A.M., Yurdaydin, C. Entecavir treatment of chronic hepatitis D (2012) Clinical Infectious Diseases, 55 645-650.

72.  Toy, M., Onder, F.O., Idilman, R., Kabacam, G., Richardus, J.H., Bozdayi, M., Akdogan, M., Kuloglu, Z., Kansu, A., Schalm, S., Yurdaydin, C. The cost-effectiveness of treating chronic hepatitis B patients in a median endemic and middle income country (2012) European Journal of Health Economics, 13 663-676.

73.  Heidrich, B., C. Serrano, B., Idilman, R., Kabaçam, G., Bremer, B., Raupach, R., Önder, F.O., Deterding, K., Zacher, B.J., Taranta, A., Bozkaya, H., Zachou, K., Tillmann, H.L., Bozdayi, A.M., Manns, M.P., Yurdaydin, C., Wedemeyer, H. HBeAg-positive hepatitis delta: Virological patterns and clinical long-term outcome (2012) Liver International, 32 1415-1425.

74.  Kabaçam, G., Dalekos, G.N., Ca̧kaloglu, Y., Zachou, K., Bock, T., Erhardt,A., Zeuzem, S., Tabak, F., Yalçin, K., Bozdayi, A.M., Dienes, H.P., Bozkaya, H., Manns, M.,  Wedemeyer, H., Yurdaydin, C. Pegylated interferon-based treatment in patients with advanced liver disease due to chronic delta hepatitis (2012) Turkish Journal of Gastroenterology, 23 560-568.

75.  Dinç, B., Koyuncu, D., Karatayli, S.C., Berk, E., Karatayli, E., Parlak, M., Celik, I., Akgüç, M., Sertöz, R., Berktaş, M., Bozdayi, G., Bozdayi, A.M. Molecular characterization of hepatitis A virus isolated from acute infections in Turkey (2012) Turkish Journal of Gastroenterology, 23 714-719.

76.  Karatayli, E., Idilman, R., Karatayli, S.C., Cevik, E., Yakut, M., Seven, G., Kabaçam, G., Bozdayi, A.M., Yurdaydin, C. Clonal analysis of the quasispecies of antiviralresistant HBV genomes in patients with entecavir resistance during rescue treatment and successful treatment of entecavir resistance with tenofovir (2013) Antiviral Therapy, 18  77-85.

77.  Şimşek, C., Sónmez, O., Yurdakul, A.S., Ózmen, F., Zengin, N., Keyf, A.I., Kubilay, D., Gülbahar, O., Karatayli, S.C., Bozdayi, M., Óztürk, C. Importance of serum SELDI-TOF-MS analysis in the diagnosis of early lung cancer (2013) Asian Pacific Journal of Cancer Prevention, 14  2037-2042.

78.  Karatayli, S.C., Ulger, Z.E., Ergul, A.A., Keskin, O., Karatayli, E., Albayrak, R., Ozkan, M., Idilman, R., Yalcin, K., Bozkaya, H., Uzunalimoǧlu, O., Yurdaydin, C., Bozdayi, A.M. Tumour necrosis factor-alpha, interleukin-10, interferon-gamma and vitamin D receptor gene polymorphisms in patients with chronic hepatitis delta (2014) Journal of Viral Hepatitis, 21 297-304.

79.  Karatayli, E., Altunoǧlu, Y.T., Karatayli, S.C., Alagöz, S.G.K., Çinar, K., Yalçin, K., Idilman, R., Yurdaydin, C., Bozdayi, A.M. A one step real time PCR method for the quantification of hepatitis delta virus RNA using an external armored RNA standard and intrinsic internal control (2014) Journal of Clinical Virology, 60 11-15.

80.  Kabaçam, G., Wedemeyer, H., Savaş, B., Keskin, O., Dalekos, G., Tabak, F., Idilman, R., Erhardt, A., Yalçin, K., Bozdayi, M.A., Bozkaya, H., Manns, M., Dienes, H., Yurdaydin, C., Berg, T.,  Böcher, W., Bohle, H., Buggisch, P., Cornberg, M.,  E rs̈ oz, G., Feyerabend, S., Hinrichsen, H., Manok, M., Häussinger, D., Herzog, W., Hofmann, W.P., Plein, K., Hardt, H., Porst, H., Mederacke, I., Rigopoulou, E.I., Sentürk, H., Wagner, E.K.V. Role of immunohistochemistry for hepatitis D and hepatitis B virus in hepatitis delta (2014) Liver International, 34 1207-1215.

81.  Karatayli, E., Altunoǧlu, Y.T., Karatayli, S.C., Yurdaydin, C., Bozdayi, A.M. Free circulating nucleic acids in plasma and serum as a novel approach to the use of internal controls in real time PCR based detection (2014) Journal of Virological Methods, 207 133-137.

82.  Keskin, O., Örmeci, A.Ç., Baran, B., Kabaçam, G., Tüzün, A., Karatayli, E., Akyüz, F., Karatayli, S., Bozdayi, A.M., Önel, D., Badur, S., Idilman, R., Kaymakoglu, S., Yurdaydin, C. Efficacy of tenofovir in adefovir-experienced patients compared with treatment-naive patients with chronic hepatitis b (2014) Antiviral Therapy, 19 543-550.

83.  Akgüç, M., Karatayli, E., Çelik, E., Koyuncu, D., Çelic, I., Karatayli, S.C., Özden, A., Bozdayi, A.M. Production of a recombinant caga protein for the detection of helicobacter pylori caga antibodies [Helicobacter pylori CagA Antikorlarimn Saptanmasi için Rekombinant Bir CagA Proteininin Üretilmesi] (2014) Mikrobiyoloji Bulteni, 48 402-412.

84.  Alagöz, G.K., Karatayli, S.C., Karatayli, E., Çelik, E., Keskin, O., Dinç, B., Çinar, K., Idilman, R., Yurdaydin, C., Bozdayi, A.M. Hepatitis C virus genotype distribution in Turkey remains unchanged after a decade: Performance of phylogenetic analysis of the NS5B, E1, and 5UTR regions in genotyping efficiency (2014) Turkish Journal of Gastroenterology, 25 405-410.

85.  Karatayli, S.C., Bozdayi, M., Karatayli, E., Öztürk, T., Husseini, A.A., Albayrak, R., Özkan, M., Kalaylioğlu, Z., Yalçin, K., Çinar, K., Idilman, R., Yurdaydin, C. Interleukin-28 gene polymorphisms may contribute to HBsAg persistence and the development of HBeAg-negative chronic hepatitis B (2015) Liver International, 35  846-853.

86.  Biçeroğlu, S.U., Karatayli, E., Bayram, A., Turhan, A., Değirmenci, A., Aydinok, Y., Bozdayi, A.M., Sertöz, Ş.R. Investigation of West Nile virus among healthy blood donors in the western part of Turkey (2015) Turkish Journal of Medical Sciences, 45  84-88.                                                                           

 

   III.        Uluslararası Kitap Bölümleri

1.     Yurdaydın C, Jones EA: Hepatic encephalopathy (Book Chapter). In: Principle and Practice of Gastroenterology and Hepatology, 2nd edition, G. Gitnict, eds., Elsevier Science Publishing Co., Inc. 1994; pp. 985-995

    1. Wedemeyer H, Yurdaydin C. Delta hepatitis. In: Handbuch hepatitis B- Diagnostik, Verlauf, Therapie.Uni-Med Verlag AG, HL Tillmann, ed., 2. Auflage, 2010, pp. 96-102
    2. Yurdaydin C, Bozdayi AM, Idilman R, Bozkaya H. New drugs for hepatitis B: what is in the pipeline? In: Clinical Dilemnas in Viral Liver Disease. Wiley-Blackwell Publ., GR Foster & KR Reddy eds., 2010, pp. 226-9
    3. Yurdaydin C, Idilman R. Hepatic encephalopathy.  Textbook of Hepato-Gastroenterology (in press)

   IV.        Projeler

 

1.     Evaluating initial and sustained response rate based on the viral load and genotype of hepatitis C virus. Çok merkezli çalışma Scherring-Plough International tarafından desteklendi. 1998 Araştırmacı.

2.     Importance of hepatitis C virus genetic heterogeneity (quasispecies) in patients with    chronic C hepatitis during interferon alpha 2A therapy. Çok merkezli çalışma.  Roche.    Araştırmacı.

3.     Viral etiology of chronic liver disease in Turkey. Çok merkezli çalışma. ICGEB tarafından desteklendi.

Araştırmacı.

4.     Karaciğer Hepatit B-C Virüsü (Hepatit B virus DNA , hepatit C virus RNA tüm genomlarının klonlanması) DPT tarafından desteklendi.      98K120770

Proje Yürütücüsü

5.   Hepatit virüs infeksiyonlarında konağa ait genetik faktörler Ankara Üniversitesi Bilimsel Araştırma Projesi                          2003.08.09.150

Proje Yürütücüsü

6.   İnflamatuar Barsak Hastalıklarının moleküler genetiği

Ankara Üniversitesi Biyoteknoloji Enstitüsü Araştırma Projesi

Proje Yürütücüsü 2004/134

7.   Adefovir terapisi altında entecavir direnci gelişen hastalardaki  viral genetik heterojenite havuzunun evrimi. Ankara Üniversitesi Bilimsel Araştırma Projesi 08A330004

Araştırmacı.

8.   Hepatit B Virüs Enfeksiyonlu hastalarda anti-viral direnç gelişmesinde viral havuzdaki

varyantların evriminin “Ultradeep pyrosequencing” yöntemi ile karakterizasyonu Ankara Üniversitesi Bilimsel Araştırma Projesi                2011                     

Proje Yürütücüsü

9.   Hepatit Delta Virüs Enfeksiyonlu hastalarda tedavi öncesi ve sırasındaki HDV viral

havuzundaki varyantların evriminin “Ultradeep pyrosequencing” yöntemi ile karakterizasyonu Ankara Üniversitesi Bilimsel Araştırma Projesi   2011 

Araştırmacı.

10.  Generalize Agresif Periodontitis Patogenezinde Nükleer Faktör Kappa-B Yolağının Rolü Ankara Üniversitesi BAP projesi,               2013-2014

Araştırmacı.

11.  11- Türkiye’de Hepatit E Virüs Seroprevalansının Yeniden Değerlendirilmesi ve HEV Viral Yükünün    

Saptanmasında Real Time PCR Temelinde Bir Yöntem Geliştirilmesi Ankara Üniversitesi BAP projesi,                2014-2016

Araştırmacı

 

12.  12-Hepatit B, C ve Delta Virüslerinin Moleküler Tanılarında Kullanılan Yöntemler için  Kalite Kontrol Serumlarının ve Ulusal Kalite Kontrol Programlarının Geliştirilmesi

TÜBİTAK, 1003 Projesi                                                                  2014-2016

Proje Yürütücüsü

 

    V.        Üyelikler

 

1.     European Society for Clinical Virology

2.     American Association for the Advancement of Science

3.     Turkish Association for the Study of the Liver

4.     European Association for the Study of the Liver

5.     Turkish Association of Gastroenterology

6.     Turkish Association of Clinical Biochemistry

7.     Turkish Association of Biochemistry

8.     Turkish Association for the Prevention of Viral Hepatitis

9.     IPPNW

10.  TUBA, Moleküler Yaşam Bilim ve Teknolojileri Öngörü Projesi, Öncelikli Bilimsel ve Teknolojik Faaliyet; Sağlık konusu panel üyesi

11.  HEPDART Toplantıları Bilimsel Komite Üyesi (2007-2015)

12.  SoGat Üyesi

 

   VI.        Patent Başvuruları

1. Real-time PCR’da nükleik asit belirlemede kullanılan bir flüoresan prob yöntemi. 2002

2. YSDD:HBV Polimeraz geninde lamivudine karşı anti viral direnci belirleyen mutasyon. 2003

3. HBV Polimeraz geninde adefovire karşı anti viral direnci belirleyen mutasyon. 2007

4. Biyolojik sıvılarda dolaşan serbest nükleik asitlerin tüm DNA ve RNA çoğaltma yöntemlerinde internal kontrol olarak kullanılması. 2013

 

 VII.        Alınan Uluslararası Patentler

1.     HBV Polimeraz geninde lamivudine karşı anti viral direnci belirleyen YSDD mutasyonu

2.     HBV Polimeraz geninde adefovire karşı anti viral direnci belirleyen mutasyon

 

VIII.        Patent Lisans Devri

1. HBV Polimeraz geninde lamivudine karşı anti viral direnci belirleyen mutasyon.

2. Innogenetics Biotechnology Ltd. Belgium, 2002

3. HBV Polimeraz geninde adefovire karşı anti viral direnci belirleyen mutasyon.

4. Innogenetics Biotechnology Ltd. Belgium 2004