PROF.DR. BELMA TURAN    
Adı : BELMA
Soyadı : TURAN
E-posta : bturan@medicine.ankara.edu.tr
Tel : 0312 5958186
Ünvan : PROF.DR.
Birim : TIP FAKÜLTESİ
Bölüm : TEMEL TIP BİLİMLERİ BÖLÜMÜ
Kişisel Akademik Bilgiler

ADI SOYADI:

Belma Turan

DİPLOMA DERECESİ:

Doktora

AKADEMİK ÜNVANI :

Prof. Dr.

YABANCI DİL BİLGİSİ:

İnglizce

DOĞUM TARİHİ ve YERİ:

1953, Silifke

MEDENİ HALİ :

Evli

AKADEMİK BİRİMİ :

Biyofizik Anabilim Dalı

YERLEŞKE :

Morfoloji Binası

İŞ ADRESİ:

Ek Bina, Sihhiye

İŞ TEL :

5958186

FAKS NO:

3106370

CEP TELEFONU :


E-MAİL :

belma.turan@medicine.ankara.edu.tr

KİŞİSEL WEB SAYFASI  :

-

KISA ÖZGEÇMİŞ:

 

 

 

 

 

 

1982 yılında Biyofizik bilim doktoru, 1987, Biyofizik Doçenti, ve 1993 yılında Biyofizik bilim Dalında Profesör ünvanlarını almış olup, 1977 yılından itibaren Tıp Fakülteside çalışmaktadır.

 

TEMEL EĞİTİM VE AKADEMİK

GELİŞİM :

 

Tıp Fakültesi Medikal Fizik Kürsüsü, Fizyoloji Kürsüsü, ve Biyofizik Anabilim Dalı

DİPLOMALAR :

 

 

Fizik lisans, Biyofizik doktora

BİLİMSEL DERNEK VE KURUMLARDA ÜYELİKLER:

 

Türk Biyofizik Derneği, Türk Fizyolojik Bilimler Derneği,

American Biophysical Society, Fellow of International Academy of Cardiovascular Sciences, International Society of Heart Research

Reviewer and panelist in projects of TUBITAK (THE SCIENTIFIC AND TECHNOLOGICAL RESEARCH COUNCIL OF TURKEY

Reviewer and panelist in EU F7 frame Reviewer and panelist in EU Horizon 2020

BİLİMSEL DERGİLERDE

 HAKEMLİK:

 

Experimental & Clinical cardiology, Cardiovascular Toxicology, Biological Trace Element Research, Molecular & Cellular Biochemistry, World Journal of Diabetology, Diabetes Review Letters, International Journal of Biomedical Sciences, Molecular Biology Reports, J. Cardiology and Therapy

ARAŞTIRMA ALANLARI:

Cardiovascular sistem elektrofizyolojisi

Genel elektrofizyolojik teknikler

Hücre içi iyon derişimleri

Antioksidan savunma

Çinko ve hücreiçi homeostazı.

Kardiak elektrofizyoloji

Kalsium iyon regülasyonu

Çinko iyon regülasyonu

Oksidan stres

Antioksidanlar

Diyabetik kardiyomiyopati

KATILDIĞI VEYA YÜRÜTTÜĞÜ PROJELER:

1- Tübitak SBAG-111S042 (Yürütücü)

2- Tübitak SBAG-109S267 (Yürütücü)

3- Tübitak MISAG-27 (Yardımcı araştırmacı)

4- Tübitak SBAG-1253 (Yardımcı araştırmacı)

5- Tübitak SBAG-AYD-69 (Yürütücü)

6- Tübitak SBAG-1732 (Yürütücü)

7- Tübitak  SBAG–3056104S591 (Yürütücü)

8- Tübitak SBAG–10105S149 (Yürütücü)

9- Tübitak SBAG-107S304 (Yürütücü)

10- Tübitak SBAG-107S427 (Yürütücü)

11-  BAP 90-09-00-28 (Yürütücü)

12-   BAP  98-09-00-05 (Yürütücü)

13-   BAP  99-09-00-10 (Yürütücü)

14-   BAP  2001-08-09-061 (Yürütücü)

15-  BAP  2003-08-09-110  (Yürütücü)

16-  BAP  2003-08-09-098 (Yürütücü)

17-  DPT 99K-120190 (Yürütücü)

18-  DPT 2003K-120-240 (Yürütücü)

19- DPT 2001K-120-240 (Yürütücü)

20- BAP 2006-08-09-233

21- BAP 09B3330011

22- BAP 12B3330005

23-Tübitak SBAG-109S267 (COST) (Yürütücü)

24-Tübitak SBAG-111S042 (Yürütücü)

25-Tübitak SBAG-113S466 (COST) (Yürütücü)

26-Tübitak SBAG-113S296 (Araştırmacı)

27-Tübitak SBAG-214S254 (Yürütücü)

28-Tübitak SBAG-216S979 (Yürütücü)

ULUSLARARASI YAYINLAR :

 


1. Delilbaşı E., Turan B., Yücel E., Temizer A., Kır S. The quantitative investigation of infrared Laser effects on the level of copper and zinc in various tissues, Clinical Physics and Physiological Measurements, 9(4), 375-377,1988.

2. Delilbaşı E., Turan B., Yücel E., Şaşmaz R., Işımer A., Sayal A. Selenium and Behçet's Disease, Biological Trace Element Research, 28(1), 21-25, 1991.

3. Turan B., Dalay N., Delilbaşı E. A Possible Relationship Between Serum Satellite DNA and Cellular Antioxidative Mechanism, Spectroscopy Letters, 24(6), 865-871, 1991.

4. Turan B., Yılmaz A., Dalay N. Effects of Selenium Supplementation on the NMR Proton Relaxation Time Tl in Plasma, Spectroscopy Letters 25(8), 1405-1410, 1992.

5. Turan B., Delilbaşı E., Dalay N., Sert S., Afrasyap L., Sayal A. Serum Selenium and Glutathione-Peroxidase Activities and Their Interaction with Toxic Metals in Dialysis and Renal Transplantation Patients, Biological Trace Element Research, 33(3), 95-102, 1992.

6. Turan, B., Delilbaşı E., Sınav, B., Akkaş, N. Zinc-Calcium Interaction in heparin Induced osteoporotic Rabbit Plasma, Trace Elements and Electrolytes, 13 (3), 138-142, 1996.

7. Turan, B., Desilets, M., Açan, L. N., Hotomaroğlu, Ö., Vannier, C., Vassort, G. Oxidative Effects of Selenite on Rat Ventricular Contractility and Ca Movements, Cardiovascular Research, 32, 351-361, 1996.

8. Turan B., Koç E., Zaloğlu N. Deficiency and Toxicity of Selenium Alter the Acetylcholine stimulated contraction of Isolated Rabbit Ileum. Trace Elements and Electrolytes, 14(1), 13-18, 1997.

9. Turan B., Zaloğlu N., Koç E., Saran Y., Akkaş N. Dietary Selenium and Vitamin E Induced Alterations in Some Rabbit Tissues. Biological Trace element Research, 58 (1-2), 1-14, 1997.

10. Turan B., Fliss H., Desilets M. Oxidant-Induced Alteration of Inracellular Free-Zn2+ Concentration in Rabbit Ventricular Myocytes, Am. J. Physiology, 272, (Heart Circ.Physiol. 41), H2095-H2106, 1997.

11. Turan B., Balçık C., Akkaş N. Effect of Dietary Selenium and Vitamin E on the, Biomechanical Properties of Rabbit Bones. Clinical Rheumatology, 16(5), 441-449, 1997.

12. Akkaş N., Yeni Y. N., Turan, B., Delilbaşı, E., Günel, U. Effect of Medication on Biomedical Properties of Rabbit Bones: Heparin Induced Osteoporosis, Clin. Rheumatology, 16(6), 585-595, 1997.

13. Turan. B, Koç E., Hotomaroğlu O., Kızıltan E., Yıldırım S., Demirel E. Dose and Tissue Dependent Effects of Sodium Selenite on Muscle Contraction. Biological Trace Element Research, 62, 265-280, 1998

14. Baştuğ M., Ayhan S., Turan B. The Effects of Altered Selenium and Vitamin E Nutritional Status on Learning and Memory of Third-generation Rats, Biol. Trace Elem. Research, 64,151-160, 1998.

15. Demirel-Yılmaz E., Dinçer D., Yılmaz G., Turan B. Selenium and Vitamin E alter the microvascular permeability of rat organs. Biological Trace Element Research, 64, 161-168, 1998.

16. Turan B., Hotomaroğlu Ö., Kılıç M., Demirel-Yılmaz E. Cardiac Dysfunction induced by low and high diet antioxidant levels comparing selenium and vitamin E in rats. Regulatory Toxicology and Pharmacology, 29, 142-150, 1999.

17. Turan B., Saran Y., Can B., Güven M.C., Sayal A.  Effect of high dietary selenium on the ultrastructure of rabbit cardiac muscle cell. Med. Sci. Res., 1999, 27(12); 795-799.

18. Ulusu N.N., N.L. Açan, Turan B., Tezcan E.F. The effect of selenium on glutathione redox cycle enzymes of some rabbit tissues. Trace Elements and Electrolytes, 2000, 17(1); 25-29.

19. Sayar K., M. Ugur, Gürdal H., Onaran O., Hotomaroğlu Ö., Turan B. Effect of dietary selenium intake on β-adrenergic response of L-type Ca-current and β-adrenoceptor-adenylate cyclase coupling in rat heart. J. Nutrition, 2000, 130; 733-740.

20. Yılmaz G., Demirel-Yılmaz E., Turan B. Disulfonic stilbene prevents selenite-induced cataract in rat pup lens. Biol.Trace Elem. Res. 2000, 75; 129-138

21. Turan B., Bayarı S., Balçık C., Severcan F., Akkaş N. A biomechanical and spectroscopic study of bone from rats with selenium deficiency and toxicity. Biometals. 2000, 13; 113-121.

22. Yılmaz G., Turan B., Çelebi N., Yılmaz N., Demirel-Yılmaz E. Prevention of selenite-induced opacification and biochemical changes in the rat pup lens through amiloride pretreatment. Current Eye Res. 2000, 20(6); 454-461.

23. Severcan F., Toyran N., Kaptan N., Turan B.  Fourier Transform Infrared study of the effect of diabetes on rat liver and heart Tissues in the C-H region. Talanta, 2000, 53; 55-59.

24. Ugur M., Turan B. Adenosine triphosphate alters the selenite-induced contracture and negative inotropic effect on cardiac muscle contractions. Biol. Trace Elem. Res. 2001, 79(3); 235-245.

25. Turan B., Açan N.L., Ulusu, N.N., Tezcan E.F. A comparative study on effect of dietary selenium on some antioxidant enzyme activities of liver and brain tissues. Biol. Trace Elem. Res. 2001,81;141-152.

26. Ugur M., Ayaz M., Ozdemir S., Turan B. Toxic concentration of Selenite shortens repolarization phase of action potential in rat papillary muscle. Biological Trace Element Research, 2002; 89(3):  227-38.

27. Ayaz M., Can B., Ozdemir S., Turan B. Protective effect of selenium treatment on diabetes-induced myocardial structural alterations. Biological Trace Element Research, 89(3): 215-226, 2002.

28. Ulusu N.N., Açan N.L., Turan B., Tezcan E.F. Inhibition of glutathione reductase by cadmium in some rabbit tissues and the protective role of dietary selenium. Biol. Trace Elem. Res. 91(2); 151-156, 2003.

29. Turan B. Zinc-induced changes in ionic currents of cardiomyocytes. Biol. Trace Element Res. 94(1); 49-60, 2003.

30. Severcan F., Kaptan N., Turan B. Fourier transform infrared spectroscopic studies of diabetic rat heart crude membranes. Spectroscopy, 17; 569-577, 2003.

31. Boyar H., Turan B., Severcan F. FTIR spectroscopic investigation of mineral structure of streptozotocin induced diabetic rat femur and tibia. Spectroscopy, 17; 627-633, 2003.

32. Ozdemir S., Ayaz M., Tuncer T., Ugur M., Turan B. Vegetable Oils used as Vitamin E vehicle effects the Electrical Activity of Rat Heart. Physiological Research, 52 (4); 767-771, 2003.

33. Ersöz G., Yakaryılmaz A., Turan B. Effect of antioxidant treatment on platelet aggregation of streptozotocin-induced diabetic rats. Thrombosis Research, 111(6); 363-367, 2003.

34. Turan B., Can B., Delilbasi E. Selenium combined with vitamin E and vitamin C retores structural alterations of bones in heparin-induced osteoporosis. Clin. Rheumatol. 22(6); 432-436, 2003.

35. Turan B., Zaloglu N., Saran Y., Konukseven E., Koc E. Alterations in zinc status and tissue structures of heparin-induced osteoporotic rabbits. Trace Elem. Electrolytes. 21 (1); 33-40, 2004.

36. Ayaz M., Ozdemir S., Ugur M., Vassort G., Turan B. Effects of Selenium on altered mechanical and electrical cardiac activities of diabetic rat. Arch. Biochem. Biophy., 426, 83-90: 2004.

37. Yaras N., Turan B. Interpretation of relevance of sodium-calcium exchange in action potential of diabetic rat heart by mathematical model. Mol. Cell. Biochem. 2005, 269: 121-129.

38. Ozdemir S., Ugur M., Gürdal H., Turan B. Candesartan Treatment Restores Diabetes-Induced Alterations in Ca2+ Transients and Contractile Function of Rat Myocardium. Arch. Biochem. Biophy. 435 (1), 166-174, 2005.

39. Zhang M., Xu Y-J., Saini H. K., Turan B., Liu PP, Dhalla N. S.  TNF-a as a potential mediator of cardiac dysfunction due to intracellular Ca2+-overload. Biophysical Biochemical Research Communications. 327(1), 57-63, 2005.

40. Ayaz M., Ozdemir S., Yaras N., Vassort G., Turan B.  Selenium-induced alterations in ionic currents of cardiomyocytes. Biophysical Biochemical Research Communications. 327, 163-173, 2005.

41. Ulusu N.N., Turan B. Beneficial effects of Selenium on some enzymes of diabetic rat heart. Biol Trace Elem. Res. 103 (3): 207-216, 2005.

42. Can B., Ulusu N.N., Acan N.L., Saran Y., Turan B. Selenium treatment protects diabetes-induced biochemical and ultrastructural alterations in liver tissue. Biol Trace Elem. Res. 105(1-3): 135-50, 2005.

43. Ozdemir S., Ayaz M., Can B., Turan B. Ultrastructural Alteration of Experimental Diabetic Rat Bone and its Improvement by Selenite Treatment. Biol. Trace Elem. Res. 107, 167-179, 2005.

44. Yaras N, Ugur M, Ozdemir S, Gurdal H, Purali N, Lacampagne A, Vassort G, Turan B. Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart. Diabetes, 2005 Nov;54(11):3082-8.

45. Turan B, Saini HK, Zhang M, Prajapati D, Elimban V, Dhalla NS. Selenium improves cardiac function by attenuating the activation of NF-kappaB due to ischemia-reperfusion injury. Antioxid Redox Signal. 2005 Sep-Oct;7(9-10):1388-97.

46. Zhang M, Xu YJ, Saini HK, Turan B, Liu PP, Dhalla NS. Pentoxifylline attenuates cardiac dysfunction and reduces TNF-alpha level in ischemic-reperfused heart. Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H832-9. Epub 2005 Apr 15.

47. Toyran N, Lasch P, Naumann D, Turan B, Severcan F. Early alterations in myocardia and vessels of the diabetic rat heart: an FTIR microspectroscopic study. Biochem J. Aug 1;397 (3):427-36, 2006.

48. Ayaz M, Turan B. Selenium Prevents Diabetes-Induced Alterations in [Zn2+]i and Metallothionein Level of Rat Heart via Restoration of Cell Redox Cycle. Am. J. Physiol., (Heart and  Circ. Physiol.), 290, H1071-80, 2006.

49. Ayaz M, Celik HA, Aydin HH, Turan B. Sodium selenite protects against diabetes-induced alterations in the antioxidant defense system of the liver. Diabetes Metab Res Rev. Jul-Aug; 22 (4):295-9, 2006.

50. Yaras N., Bilginoglu A., Vassort G., Turan B. Restoration of Diabetes-Induced Abnormal Local Ca2+ Release in Cardiomyocytes by Angiotensin II Receptor Blockade.
Am J Physiol Heart Circ Physiol. 2007 Feb;292(2):H912-20. Epub 2006 Sep 29.

51. Toyran N, Turan B, Severcan F. Selenium alters the lipid content and protein profile of rat heart: An FTIR microspectroscopic study. Arc. Biochem. Biophys. 2007 Feb 15;458(2):184-93. Epub 2007 Jan 22.

52. Bilginoglu A., Amber Cicek F., Ugur M., Gurdal H., Turan B.  The role of gender differences in b-adrenergic receptor responsiveness of normal and diabetic rat hearts. Mol Cell Biochem. 2007 Nov;305(1-2):63-9. Epub 2007 Jun 19.

53. Tuncay E., Segmen A. A., Tanriverdi E., Yaras N., Tandogan B., Ulusu N. N., Turan B.  Gender related differential effects of omega-3E treatment on diabetes-induced left ventricular dysfunction. Mol Cell Biochem. 2007 Oct;304(1-2):255-63. Epub 2007 May 26.

54. Buluc M, Ayaz M, Turan B, Demirel-Yilmaz E. Resveratrol-induced depression of the mechanical and electrical activities of the rat heart is reversed by glyburide: evidence for possible K(ATP) channels activation. Arch Pharm Res. 2007 May;30(5):603-7.

55. Toyran N, Severcan F, Severcan M, Turan B. Investigation of diabetes-induced effect on apex of rat heart myocardium by using cluster analysis and neural network approach: An FTIR study. Spectroscopy, 2007, 21: 269-278.

56. Yaras N., Tuncay E., Puralı N., Sahinoglu B., Vassort G., Turan B.  Sex-related effects on diabetes-induced alterations in calcium release in the rat heart. Am J Physiol Heart Circ Physiol. 2007 Dec; 293(6):H3584-92. Epub 2007 Sep 21.

57. Toyran N,   Severcan F., Severcan M., Turan B. Effects Of Selenium Supplementatıon On Rat Heart Apex And Right Ventricle Myocardia By Usıng FTIR Spectroscopy: A Cluster Analysıs And Neural Network Approach. Food Chemistry, 2008, 110(3): 590-597.

58. Aydemir-Koksoy A. Turan B. Selenium Inhibits Proliferation Signaling and Restores Sodium/Potassium Pump Function of Diabetic Rat Aorta. Biol Trace Elem Res. 2008, 126: 237-245. Aug 14. [Epub ahead of print]

59. Yaras N, Sariahmetoglu M, Bilginoglu A, Aydemir-Koksoy A, Onay-Besikci A, Turan B, Schulz R. Protective action of doxycycline against diabetic cardiomyopathy in rats. Br J Pharmacol. 2008 Dec;155(8):1174-84. Epub 2008 Sep 22.

60. Ozdemir S, Tandogan B, Ulusu NN, Turan B. Angiotensin II receptor blockage prevents diabetes-induced oxidative damage in rat heart. Folia Biol (Praha). 2009;55(1):11-6

61. Tuncay E, Seymen AA, Sam P, Gurdal H, Turan B. Effects of Beta-Adrenergic Receptor Blockers on Cardiac Function: A Comparative Study in Male Versus Female Rats. Can J Physiol Pharmacol, 2009, 87: 310-317.

62. Bilginoglu A, Seymen A, Tuncay E, Zeydanli E, Koksoy A, Turan B. Antioxidants but not Doxycycline Treatment Restore Depressed Beta-Adrenergic Responses of the Heart in Diabetic Rats. Cardiovasc. Tox. 2009, 9: 21-29.

63. Zeydanli E N, Turan B. Omega-3E treatment regulates matrix metalloproteinases and prevents vascular reactivity alterations in diabetic rat aorta. Can J Physiol. Pharmacol. 2009 Dec;87(12):1063-73.

64. Aydemir-Koksoy A, Bilginoglu A, Sariahmetoglu M, Schulz R, Turan B. Antioxidants Protect Diabetic Rats from Cardiac Dysfunction by Preserving Contractile Protein Targets of Oxidative Stres. J. Nutr. Biochem, 2010, 21(9): 827-833.

65. Zeydanli ES, Bilginoglu A, Tanriverdi E, Gurdal H, Turan B. Selenium restores defective beta-adrenergic receptor response of thoracic aorta in diabetic rats. Mol. Cell. Biochem. 2010 May;338(1-2):191-201. Epub 2009 Dec 18.

66. Basgut B, Kayki G, Bartosova L, Ozakca I, Seymen A, Kandilci HB, Ugur M, Turan B, Ozcelikay AT. Cardioprotective effects of 44Bu, a newly synthesized compound, in rat heart subjected to ischemia/reperfusion injury. Eur J Pharmacol. 2010 May 5. [Epub ahead of print].

67. Vassort G, Turan B. Protective role of antioxidants in diabetes-induced cardiac dysfunction. Cardiovasc Toxicol. 2010 Jun;10(2):73-86.

68. Turan B: Role of Antioxidants in Redox Regulation of Diabetic Cardiovascular Complications. Current Pharmaceutical Biotechnology, 2010, 11(8):819-36.

69. Gecer A, Yildiz N, Turan B, Calimli A. Trimethyl nanochitosan enhances dissolution properties of the poorly water soluble drug candesartan-cilexetil. Macromolecular Research, 18(10): 986-991, 2010.

70. Tuncay E, Bilginoglu A, Sozmen NN, Zeydanli EN, Ugur M, Vassort G, Turan B: Intracellular free zinc during cardiac excitation-contraction coupling: calcium and redox dependencies. Cardiovasc. Res. 89(3):634-42, 2011.

71. Turan B, Vassort G: Ryanodine receptor: a new therapeutic target to control diabetic cardiomyopathy. Antiox. Redox Sig. Focused issue, 2011 Oct 1;15(7):1847-61. Epub 2011 Apr 8.

72. Atalay M, Bilginoglu A, Kokkola T, Oksala N, Turan B. Treatments with sodium selenate or doxycycline offset diabetes-induced perturbations of thioredoxin-1 levels and antioxidant capacity. Mol Cell Biochem. 351: 125-131, 2011.

73. Kandilci HB, Tuncay E, Zeydanli EN, Sozmen NN, Turan B. Age-related regulation of excitation-contraction coupling in rat heart. J Physiol Biochem. 2011, Sep;67(3):317-30. Epub 2011 Feb 2.

74. Zeydanli EN, Kandilci HB, Turan B.  Doxycycline ameliorates diabetic vascular endothelial and contractile dysfunction in thoracic aorta. Cardiovasc. Toxicol. 2011, 11(2): 134-147.

75. Sozmen NN, Tuncay E, Zeydanli EN, Turan B.  Profound cardioprotection with timolol in female rat model of aging-related altered left ventricular function. Can. J. Physiol. Pharmacol. 2011, 89(4): 277-288.

76. Tuncay E, Zeydanli EN, Turan B. Cardioprotective effect of propranolol on diabetes-induced altered intracellular Ca2+ signaling in rat. J Bioenerg Biomembr. 2011, Dec;43(6):747-56. Epub 2011 Nov 30.

77. Turan B, Vassort G. Vitamin E in Oxidant Stress-Related Cardiovascular Pathologies: Focus on Experimental Studies. Current Pharmaceutical Design, 2011, 17(21):2155-69

78. Turan B, Tuncay E, Vassort G. Resveratrol and diabetic cardiac function: focus on recent in vitro and in vivo studies. J Bioenerg Biomembr. 2012 Apr;44(2):281-96.

79. Bilginoglu A, Kandilci HB, Turan B. Intracellular Levels of Na(+) and TTX-sensitive Na (+) Channel Current in Diabetic Rat Ventricular Cardiomyocytes. Cardiovasc Toxicol. 2013 Jun;13(2):138-47.

80. Cicek FA, Kandilci HB, Turan B. Role of ROCK upregulation in endothelial and smooth muscle vascular functions in diabetic rat aorta. Cardiovasc Diabetol. 2013 Mar 27;12:51. doi: 10.1186/1475-2840-12-51.

81. Yildirim SS, Akman D, Catalucci D, Turan B.

Relationship Between Downregulation of miRNAs and Increase of Oxidative Stress in the Development of Diabetic Cardiac Dysfunction: Junctin as a Target Protein of miR-1. Cell Biochem Biophys. December 2013, Volume 67, Issue 3, pp 1397-1408.

82. Tuncay E, Okatan EN, Vassort G, Turan B: ß-blocker timolol prevents arrhythmogenic Ca2+ release and normalizes Ca2+ and Zn2+ dyshomeostasis in hyperglycemic rat heart. PLOS ONE, 2013: Jul 29;8(7):e71014. doi: 10.1371

83. Okatan EN, Tuncay E, Turan B. Cardioprotective effect of selenium via modulation of cardiac ryanodine receptor calcium release channels in diabetic rat cardiomyocytes through thioredoxin system. J Nutr Biochem. 2013 Dec;24(12):2110-8.doi:10.1016/j. jnutbio. 2013.08.002. Epub 2013 Oct 31.

84. Ozcinar E, Okatan EN, Tuncay E, Eryilmaz S, Turan B. Improvement of functional recovery of donor heart following cold static storage with doxycycline cardioplegia. Cardiovasc Toxicol. 2014 Mar;14(1):64-73. doi: 10.1007/s12012-013-9231-1

85. Sargin AK, Can B, Turan B: Comparative Investigation of Kidney Mesangial Cells from Increased Oxidative Stress Induced Diabetic Rats by Using Different Microscopy Techniques, Mol Cell Biochem. 2014 May;390(1-2):41-9. doi: 10.1007/s11010-013-1953-7. Epub 2013 Dec 29.

86. Gokturk H, Ulusu NN, Gok M, Tuncay E, Can B, Turan B. Long-term treatment with a beta-blocker timolol attenuates renal-damage in diabetic rats via enhancing kidney antioxidant-defense system. Mol Cell Biochem. 2014 Oct;395(1-2):177-86. doi: 10.1007/s11010-014-2123-2. Epub 2014 Jun 20.

87. Amber CF, Zeynep TK, Evren O, Yusuf B, Can AK, Turan B. Di-peptidyl peptidase-4 inhibitor sitagliptin protects vascular function in metabolic syndrome: possible role of epigenetic regulation. Mol Biol Rep. 2014  Aug;41(8):4853-63. doi: 10.1007/s11033-014-3392-2.

88. Tuncay E, Okatan EN, Toy A, Turan B. Enhancement of cellular antioxidant-defence preserves diastolic dysfunction via regulation of both diastolic Zn2+ and Ca2+ and prevention of RyR2-leak in hyperglycemic cardiomyocytes. Oxid Med Cell Longev. 2014;2014:290381. doi: 10.1155/2014/290381. Epub 2014 Feb 13.

89. Turan B, Tuncay E. Regulation of cardiac β3-adrenergic receptors in hyperglycemia. Indian Journal of Biochemistry and Biophysics, 2014 Dec;51(6):483-92.

90. Cicek F A, Toy A, Tuncay E, Can B, Turan B. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress. Journal of Bioenergetics and Biomembranes, 2014 Oct; 46(5):377-87.

91. Chabosseau PL, Tuncay E, Meur G, Bellomo EA, Hessels A, Hughes S, Johnson PR, Bugliani M, Marchetti P, Turan B, Lyon AR, Merkx M, Rutter GA. Mitochondrial and ER-targeted eCALWY probes reveal high levels of free Zn2+. ACS Chem Biol. 2014 Sep 19;9(9):2111-20.

92. Okatan Esma N., Sule Kizil, Hilal Gokturk, Belgin Can, Belma Turan. High-carbohydrate diet induced myocardial remodeling in rats. Current research: Cardiology, 2015: 2(1): 5-10.

93. Okatan Esma N., Erkan Tuncay, Gaye Hafez, Belma Turan. Profiling of cardiac β-adrenoceptor subtypes in left ventricular rat heart with metabolic syndrome: Comparison with streptozotocin-induced diabetic rat. Can J Physiol Pharmacol. Can J Physiol Pharmacol. 2015 Jul;93(7):517-25. doi: 10.1139/cjpp-2014-0507.

94. Deletioglu V, Tuncay E, Toy A, Atalay M, Turan B. Immuno-spin trapping detection of antioxidant/pro-oxidant properties of zinc or selenium on DNA and protein radical formation via hydrogen peroxide. Mol Cell Biochem.  2015 Nov;409(1-2):23-31. doi: 10.1007/s11010-015-2508-x.

95. Tuncay E, Turan B. Intracellular Zn2+ Increase in Cardiomyocytes Induces both Electrical and Mechanical Dysfunction in Heart via Endogenous Generation of Reactive Nitrogen Species. Biol Trace Elem Res. 2016 Feb;169(2):294-302. doi: 10.1007/s12011-015-0423-3.

96. Turan B. A Comparative Summary on Antioxidant-like Actions of Timolol with Other Antioxidants in Diabetic Cardiomyopathy. Curr Drug Deliv. 2016;13(3):418-23.

97. Okatan EN, Durak AT, Turan B. Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction. Can J Physiol Pharmacol. 2016 Oct;94(10):1064-1073

 

98. Tükel HC, Alptekin Ö, Turan B, Delilbaşı E. Effects of metabolic syndrome on masseter muscle of male Wistar rats. Eur J Oral Sci. Eur J Oral Sci. 2015 Dec;123(6):432-8. doi: 10.1111/eos.12226.

 

99. Billur D, Tuncay E, Okatan EN, Olgar Y, Durak AT, Degirmenci S, Can B, Turan B. Interplay Between Cytosolic Free Zn2+ and Mitochondrion Morphological Changes in Rat Ventricular Cardiomyocytes. Biol Trace Elem Res. 2016 Nov;174(1):177-188.


100. Okatan EN, Durak AT, Turan B. Electrophysiological basis of metabolic-syndrome-induced cardiac dysfunction. Can J Physiol Pharmacol. 2016 Oct;94(10):1064-1073. Epub 2016 Apr 12.

 

101. Tuncay E, Bitirim VC, Durak A, Carrat GRJ, Taylor KM, Rutter GA, Turan B. Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart. Diabetes. 2017 May;66(5):1346-1358. doi: 10.2337/db16-1099. Epub 2017 Feb 23.

 

102. Egea J, Fabregat I, Frapart YM, Ghezzi P, et al. European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol. 2017 May 18;13:94-162. doi: 10.1016/j.redox.2017.05.007. [Epub ahead of print] Review.

 

103. Toy Durak A, Olgar Y, Tuncay E, Karaomerlioglu I, Kayki Mutlu G, Arioglu Inan E, Altan VM, Turan B. Onset of Depressed Heart Work is Correlated with the Increased Heart Rate and Shorten QT-Interval in High-Carbohydrate Fed Overweight Rats. Can J Physiol Pharmacol. 2017 Jul 30. doi: 10.1139/cjpp-2017-0054. [Epub ahead of print]

 

104. Olgar Y, Ozdemir S, Turan B. Induction of endoplasmic reticulum stress and changes in expression levels of Zn2+-transporters in hypertrophic rat heart. Mol Cell Biochem. 2017 Aug 28. doi: 10.1007/s11010-017-3168-9. [Epub ahead of print].

 

105. Olgar Y, Celen MC, Yamasan BE, Ozturk N, Turan B, Ozdemir S. Rho-kinase inhibition reverses impaired Ca2+ handling and associated left ventricular dysfunction in pressure overload-induced cardiac hypertrophy. Cell Calcium. 2017 Nov;67:81-90. doi: 10.1016/j.ceca.2017.09.002. Epub 2017 Sep 9.

 

106. Bitirim CV, Tuncay E, Turan B. Demonstration of subcellular migration of CK2α localization from nucleus to sarco(endo)plasmic reticulum in mammalian cardiomyocytes under hyperglycemia. Mol. Cell. Biochem. 2017, DOI: 10.1007/s11010

ULUSAL YAYINLAR :

 

1. Turan B., Oral B., Öztekin E., Güner Z. Can ESR be Used as a Diagnostic Tool in Medicine? Hacettepe Bulletin of Natural Sciences and Engineering, 11, 75-90, 1982.

2. Turan B. Hematolojik araştırmalarda Elektron Spin Rezonans, Türkiye Bilimsel ve Teknik Araştırma Kurumu Magnetik Rezonans Araştırma Ünitesi 1. Kollokyumu Notları, 67-79, 1982.

3. Turan B. Kandaki Cu2+ ve Fe3+ Metal İyonlarının Paramagnetik Özelliklerinden Yararlanarak Normal ve Hasta İnsan Kanları Arasındaki Farkların ESR Yöntemi ile İncelenmesi, Journal of Ankara Medical School, 6(4), 271-284, 1984.

4. Yılmaz A., Turan B. A Suitable Mechanism for the Explanation of NMR Spin-Lattice Relaxation Time in Human Serum, Biyokimya Dergisi, XI(3), 33-38, 1986.

5. Delilbaşı E., Yücel E., Turan B., Günhan Ö. Infrared Laserin Sağlıklı Dokulardaki Etkisinin Histopatolojik Olarak İncelenmesi, Otorinolarengoloji ve Stomatoloji Dergisi, 2(1), 53-56, 1988.

6. Turan B., Delilbaşı E., Yücel E., Temizer A., Rann H. S. Near-lnfrared Laser Light Has Effects on the Level of Various Metals in Skeletal Muscle: Is it completly Harmless?, Laser in Life Sciences, 3(2), 83-88, 1989.

7. Yavuzer S., Pehlivan F., Yıldırım G., Turan B., Güvener A. Infrared Laser Effects on Experimental Epilepsy Models: Convolsive and Anticonvolsive Effects, Turkish Journal of Research in Medical Sciences, 7(2), 81-84, 1989.

8. Dalay N., Turan B., Saydan N., Şengül Z., Özcan T., Dinçol D., İçli F., Tanalp R Determination of Circulating serum free DNA and magnesium levels in cancer patients, Journal of Ankara Medical School, 12 (4), 331-337, 1990.

9. Yavuzer S., Anadolu R, Turan B., Erdem C. The effects of free radical scavengers and infrared Laser irradiation on wound healing, Journal of Ankara Medical School, 13(4), 295-305, 1991 .

10. Turan B., Delilbaşı, E., Dalay N., Afrasyap L., Şengün Z. Therapeutic Selenium Supplementation: Activities of Glutathione Peroxidase and Superoxide Dismutase in Several Rabbit Tissues, Romanian Journal of Biophysics, 2(2), 121-127, 1992.

11. Turan B., Delilbaşı E. The serum selenium and immunoglobulins levels in healthy and cancer cases, Biyokimya Dergisi, XVII(I), 29-39, 1992.

12. Turan B., Delilbaşı E., Işımer A., Dalay N. Distribution of selenium and glutathione peroxidase in rabbits given selenite, Turkish Journal of Medical Research, 10(2), 7176, 1992.

13. Dalay N.,Turan B., Koç, E., Delilbaşı E. The Effects of in Vivo Selenium Supplementation on the Amplitude of the Spontaneous Contractions and the Responses to Acetylcoline in Isolated Rabbit Ileum, Neurobiology, 1(1), 83-90,1993.

14. Turan B., Dalay N., Afrasyap L., Delilbaşı E., Şengün Z., Sayal A., Işımer A. The Effects of Selenium Supplementation on Antioxidative Enzyme Activities and Plasma, Erythrocyte Selenium Levels, Acta Physiologica Hungarica, 81(1), 87-93, 1993.

15. Delilbaşı E., Delilbaşı L., Turan B., Dalay N. The effects of selenium supplementation on wound healing and antioxidant enzyme activities of skin lesion, Turkish Journal of Medical Research, 11(2), 54-58, 1993.

16. Turan B., Yeni Y. N., Günel U., Delilbaşı E., İrfanoğlu B., Akkaş N. Biomechanical Characteristics of Osteoporotic Bones in Rabbits: an Experimental Study, Engineering Systems Design and Analysis, 64-4, 91-95, 1994.

17. Turan B., Balçık C., Delilbaşı E., Akkaş N. Effect of Dietary Selenium and Vitamin E on the Biomechanical Properties of Bones and Skeletal Muscles, Engineering Systems Design and Analysis, Vol.77-5, 113-116, 1996

18. Hotomaroğlu Ö., Turan B. PCSoft program for the acquisition and analysis of voltage-dependent properties of macroscopic calcium channel currents in rat ventricular myocytes. Journal of Ankara Medical School, 20(1), 1-8, 1998.

19. Turan B., Saran Y., Can B., Güven M.C., Sayal A.  Effect of high dietary selenium on the ultrastructure of rabbit cardiac muscle cell. Med. Sci. Res., 1999, 27(12); 795-799.

20. Can B., Ugur M., Güven C.M., Saran Y., Turan B. Ultrastructural changes of cardiac cells in streptozotocin-induced diabetic rats. Klinik Laboratuvar Araştırma Dergisi, 2001, 5(3); 87-92.

21. Ulusu N.N., Açan N.L., Turan B., Tezcan E.F. Effect of cadmium ion on glutathione reductase and glutathione peroxidase activity of rat liver and the relationship with dietary selenium. Türk Biyokimya dergisi, 2002, 27(2); 43-46.

22. Delilbasi C., Demiralp S., Turan B. Effects of selenium on the structure of the mandible in experimental diabetics. J Oral Sci. 2002, 44(2); 85-90.

23. Koc E., Ayaz M., Saran Y., Turan B. Relationship between structural alterations of ileal smooth muscle and altered responses to acetylcholine in streptozotocin-induced diabetic rats. Journal of Medical Research, 2002; 20(2): 65-71.

24. Zeydanli E N., Turan B. Antioxidant treatments improve diabetes induced endothelium-dependent vascular dysfunction. Erciyes Medical Journal, 2009, 31(3): 193-200.


25. Toy A, Tutar M F, Olgar Y, Okatan E N, Değirmenci S, Aksu S, Aydın İ,  Bıçakçı E,  Doğan M, Gündüz A, Tuncay E, Turan B. Pioglitazonun Metabolik Sendromlu Sıçan Kalp Fonksiyonuna Etkisinin Elektrofizyolojik Yöntemlerle İncelenmesi. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 2015, 68(1): DOI: 10.1501/Tıpfak_000000881.

 

MEDİKAL KİTAPLARDA BÖLÜM YAZARLIĞI:

1- Yılmaz A., Turan B. Measurements and Calculations of NMR spin-lattice relaxation time in human blood, Proceedings of the II. International conference on applications of physics to Medicine and Biology, Ed: Z. Bajker, P. Baxa, C. Franconi, World Scientific publ.co. Singapure, 557-558,1984

2- Yılmaz A., Altıntaş C., Turan B. NMR relaxation mechanism in serum from healthy subjects, Proceedings of the XXII Congress of Ampere on Magnetic Resonance and Related Phenomena, Ed: K.A. Muller, R. Kind, J. Roos, Zurich, 483-484,1984

3- Yıldırım G., Zaloğlu N., Turan B., Temizer A., Koç E., Timur A. The Effects of Lithium on the Levels of Trace Elements in Liver and Spleen and Serum, Trace Elements in Health and Disease: Trace’89. Ed. Yüregir G. T., Donma O., Kayrýn L., Türkiye, 403-408,1991

4- Zaloğlu N., Yıldırım G., Koç E.,Turan B., Saran Y.,Temizer A., Timur A. The Effects of Lithium on Liver and Spleen Tissues and Serum, Trace Elements in Health and Disease: Trace’89. Ed. Yüregir G. T., Donma O., Kayrin L., Türkiye, 397-402, 1991

5- Yavuzer S., Turan B. Infrared Laser Effects on Excitation-Contraction Coupling and the Level of Some Metals of skeletal Muscle, Trace Elements in Health and Disease: Trace’89.  Ed. Yüregir G. T., Donma O., Kayrýn L., Türkiye, 291-297, 1991

6- B. Turan. Relationship Between Redox Regulation and b-Adrenergic Responses in the Heart. Advances in Biochemistry in Health and Disease, Signal Transduction in Cardiovascular System in Health and Disease, Ed: A. Srivastava and M. Srivastava, Springer, 2008.

7- B. Turan, G. Vassort. Cardioprotective Roles of Selenium in Diabetes. Nutritional and Therapeutic Intervention of Diabetes and Metabolic Snydrome. Ed: D. Bagchi and S. Nair, Ensevier, 2011.


8- M. Ayaz and B. Turan. A critical balance between oxidative stress and antioxidant defence in cardiovascular system under hyperglycemia: A summary of experimental studies. Advances in Biochemistry in Health and Disease: Volume 9, Diabetic Cardiomyopathy. Biochemical and Molecular Mechanisms, Springer, 2013. Ed: B. Turan and N. S. Dhalla, 2013.

9- S. Ozdemir, N. Yaras and B. Turan: Sex differences and diabetes mellitus in cardiovascular system. Advances in Biochemistry in Health and Disease: Volume 9, Diabetic Cardiomyopathy. Biochemical and Molecular Mechanisms, Springer, 2013. Ed: B. Turan and N. S. Dhalla, 2013.

 

10-Belma Turan and Naranjan S. Dhalla: Advances in Biochemistry in Health and Disease: Volume 9, Diabetic Cardiomyopathy. Biochemical and Molecular Mechanisms, Springer, 2013. ISBN: 978-1-4614-9316-7.