PROF.DR. ESİN EMİNE AKI YALÇIN    
Adı : ESİN EMİNE
Soyadı : AKI YALÇIN
E-posta : esinaki@ankara.edu.tr
Tel : 203 30 64
Ünvan : PROF.DR.
Birim : ECZACILIK FAKÜLTESİ
Bölüm : ECZACILIK MESLEK BİLİMLERİ BÖLÜMÜ
Kişisel Akademik Bilgiler

Eğitim ve Yönetim Geçmişi

1974-1978: B.Sc. at Gazi University, Faculty of Pharmacy
1983: Ph.D. at Ankara University Faculty of Pharmacy Department of Pharmaceutical Chemistry
1986-1987: Assistant Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry 
1987: Associate Professor Degree
1988-1993: Associate Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
1993-Present: Full Professor at Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry
1999-2002: Ankara University, Faculty of Pharmacy, Head of the Department of Pharmaceutical Chemistry
2003-2006: Ankara University, Faculty of Pharmacy, Chair of Pharmaceutical Sciences Division
2007-Present: President of the Computer Aided Drug Design and Development Society in Turkey
2008-2012: Assistant to the President of Ankara University

Bildiği Diller

  •  Turkish (Native Language)
  •  English (Fluent)
  •  Spanish (Beginner Level)

Danışman olunan Doktora Tezleri

  •  Ozlem TEMIZ, 1998, “Synthesis, Structure Elucidation, Microbiological Activity and Quantitative Structure-Activity Relationship Analysis of 5-(2-Furylcarboxamido)-, 5-(2-Thienylcarboxamido)-, 5-Benzamido- and 5-phenylacetamido- 2-phenylbenzoxazole Derivatives” 
  •  Sabiha ALPER-HAYTA, 2009, "Synthesis, Structure Elucidation, Antimicrobial Activity and Molecular Modelling Studies of Novel Benzoxazole compounds"

Danışman olunan Master Tezleri

  •  Hulya TURGUT, 1989, “Synthesis, Structure Elucidation and Microbiological Activity of 5-Substituted-2-(3-pyridyl)benzoxazole Derivatives”
  •  Ozlem TEMIZ, 1991, “Synthesis, Structure Elucidation and Microbiological Activity of 5-Methyl-2-(p-substitutedbenzyl)benzoxazole Derivatives “
  •  Cengiz ERTAS, 1998, “Studies on Synthesis, Structure Elucidation and Microbiological Activity of Possible Metabolites of Benzoxazoles, 4-Substituted-N-(2-hydroxy-5-nitrophenyl)benzamide ve Benzene-acetamide Derivatives” 
  •  Kamuran Kadri BINGOL, 1994, “Studies on Synthesis and Microbiological Activity of Possible Metabolites of Benzoxazoles”
  •  Sabiha ALPER, 2002, “Studies on Synthesis, Structure Elucidation and Microbiological Activity of Ethyl-3,4-dihydro-6- and/or 7-substituted-3-oxo-2H-1,4-benzoxazine-2-acetate ve ethyl 3,4- dihydro -N(4)-methyl-6- and/or 7-substituted-3-oxo-2H-1,4-benzoxazine-2-acetate”
  •  Murat YILMAZ, 2004, “Oral Antidiabetic Drugs”

Yayın Kurulu Üyelikleri

  •  ARKIVOC Journal
  •  Current Computer Aided Drug Design Journal
  •  Journal of Faculty of Pharmacy of Ankara University

Sempozyum ve Toplantı Organizasyonları

  •  Chair of the “15th European Symposium on Quantitative Structure-Activity Relationships”, Istanbul, September 05-10, 2004.
  •  Chair of the Organizing Committee of the "Workshop on Computer Aided Drug Design & Development", Istanbul-TURKEY, February 02-05, 2007.
  •  Chair of the Organizing Committee of the “6th AFMC International Medicinal Chemistry Symposium", Istanbul-TURKEY, July 01-04, 2007.

Üyelikler

  •  International QSAR and Modelling Society
  •  American Chemical Society
  •  Ankara University Alumni Association
  •  Turkish Association of Pharmaceutical and Medicinal Chemistry 
  •  Computer Aided Drug Design and Development Society (CADD&D Society) in Turkey
  •  The Society of Pharmaceutical Sciences of Ankara (FABAD)
  •  Development Association of Ankara University, Faculty of Pharmacy
  • 80
    ZILIFDAR, F., ALPER-HAYTA, S., YILMAZ, S., KAPLAN-OZEN, C., FOTO, E., AYDOGAN, Z., YILDIZ, I., AKI, E., YALCIN, I., DIRIL, N., "Genotoxic potentials and eukaryotic DNA topoisomerase I inhibitory effects of some benzoxazine derivatives", Med. Chem. Res., 23(1), 480-486, (2014). DOI: 10.1007/s00044-013-0658-5 [tüm metin]
  • 79
    YILMAZ, S., YALCIN, I., KAYNAK-ONURDAG, F., OZGEN, S., YILDIZ, I., and AKI, E., "Synthesis and In vitro Antimicrobial Activity of Novel 2-(4-(Substituted-carboxamido)benzyl / phenyl)benzothiazoles", Croat. Chem. Acta, 86(2), 223-231, (2013). Doi: 10.5562/cca2064 [tüm metin]
  • 78
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., YILMAZ, S., YILDIZ, I., AKI, E., "Quantum mechanical and spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations of 2-(p-nitrobenzyl) benzoxazole", Journal of Molecular Structure, 1046, 92-100, (2013). Doi: 10.1016/j.molstruc.2013.04.044 [tüm metin]
  • 77
    KAPLAN-OZEN, C., TEKINER-GULBAS, B., FOTO, E., YILDIZ, I., DIRIL, N., AKI, E., YALCIN, I., "Benzothiazole derivatives as human DNA topoizomerase IIα inhibitors", Med. Chem. Res., 22(12), 5798-5808, (2013). DOI: 10.1007/s00044-013-0577-5 [tüm metin]
  • 76
    BHAGYASREE, J.B., VARGHESE, H.T., PANICKER, C.Y., SAMUEL, J., VAN ALSENOY, C., BOLELLI, K., YILDIZ, I., AKI, E., "Vibrational spectroscopic (FT-IR, FT-Raman, 1H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole", Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 102, 99-113, (2013). doi:10.1016/j.saa.2012.09.032 [tüm metin]
  • 75
    BOLELLI, K., YALCIN, I., ERTAN-BOLELLI, T., OZGEN, S., KAYNAK-ONURDAG, F., YILDIZ, I, AKI, E., "Synthesis of novel 2-[4-(4-substitutedbenzamido/phenylacetamido)phenyl]benzothiazoles as antimicrobial agents", Med. Chem. Res., 21, 3818-3825, (2012). DOI: 10.1007/s00044-011-9918-4 [tüm metin]
  • 74
    TASKIN, T., YILMAZ, S., YILDIZ, I., YALCIN, I., AKI, E., "Insight into eukaryotic topoisomerase II-inhibiting fused heterocyclic compounds in human cancer cell lines by molecular docking", SAR and QSAR Environmental Research, 23(3-4), 345-355, (2012). Doi:10.1080/1062936X.2012.664560 [tüm metin]
  • 73
    KAROLAK-WOJCIECHOWSKA, J., SZCZESIO, M., ERTAN-BOLELLI, T., AKI, E., YALÇIN, I., "Crystal structure of 4-fluoro-N-(2-hydroxy-4-nitrophenyl)benzamide, C13H9FN2O4", Z. Kristallogr. NCS, 225, 533-534, (2010). DOI: 10.1524/ncrs.2010.0234 [tüm metin]
  • 72
    KAROLAK-WOJCIECHOWSKA, J., SZCZESIO, M., ALPER-HAYTA, S., AKI, E., YALÇIN, I., "Crystal structure of 3,4-dihydro-3-oxo-6-ethoxycarbonyl-2H-1,4-benzoxazine-2-acetate, C15H17NO6", Z. Kristallogr. NCS, 225, 531-532, (2010). DOI: 10.1524/ncrs.2010.0233[tüm metin]
  • 71
    FILAK, F., TEKINER-GULBAS, B., RIEDL, Z., VASKO, G.A., EGYED, O., YALÇIN, I., AKI-SENER, E., HAJOS, G., “Ring Expansion of N-Aminobenzothiazolium Salts to Benzothiazines and Benzothiadiazines”, Acta Chim. Slov, 56, 622–628, (2009). WOS:000270787600013 [tüm metin]
  • 70
    ZEYBEK, B., DURMUŞ, Z., TEKİNER-GÜLBAŞ, B., AKI-ŞENER, E., YALÇIN, İ., KILIÇ, E., "Electrochemical Behaviors and Determinations of Some 2,5-Disubstituted Benzoxazole Compounds at the Hanging Mercury Drop Electrode", Current Pharmaceutical Analysis, 5, 21-27, (2009). WOS:000263953500003 [tüm metin]
  • 69
    ERTAN, T., YILDIZ, I., TEKINER-GULBAS, B., BOLELLI, K., TEMIZ-ARPACI, O., OZKAN, S., KAYNAK, F., YALCIN, I., AKI, E., “Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents”, European Journal of Medicinal Chemistry, 44, 501–510, (2009). doi:10.1016/j.ejmech.2008.04.001 [tüm metin]
  • 68
    TEMIZ-ARPACI, Ö., YILDIZ, I., OZKAN, S., KAYNAK, F., AKI-SENER, E., YALÇIN, I., "Synthesis and biological activity of some new benzoxazoles" European Journal of Medicinal Chemistry, 43, 1423-1431, (2008). doi:10.1016/j.ejmech.2007.09.023 [tüm metin]
  • 67
    TEKINER-GULBAS, B., FILAK, F., VASKO, G.A., EGYED, O., YALÇIN, I., AKI-SENER, E., RIEDL, Z., HAJOS, G.,“Synthesis of Novel Pyrazolo[5,1-b][1,3]benzothiazoles: A New Pericyclic Pathway”, Heterocycles, 75(8), 2005–2012, (2008). WOS:000259131300011 [tüm metin]
  • 66
    ARISOY, M., TEMIZ-ARPACI, O., YILDIZ, I., KAYNAK-ONURDAG, F., AKI, E., YALCIN, I., ABBASOGLU, U., “Synthesis, Antimicrobial Activity and QSAR Studies of 2,5-Disubstituted Benzoxazoles”, SAR and QSAR in Environmental Research, 19(5–6), 589–612, (2008). DOI: 10.1080/10629360802348738 [tüm metin]
  • 65
    YILDIZ, I., ERTAN, T., BOLELLI, K., TEMIZ-ARPACI, O.,YALCIN, I. AKI, E., "QSAR and Pharmacophore Analysis on Amides against Drug-Resistant S. aureus", SAR and QSAR in Environmental Research, 19(1-2), 101-113, (2008). DOI: 10.1080/10629360701844159 [tüm metin]
  • 64
    ALPER-HAYTA, S., ARISOY, M., TEMIZ-ARPACI, Ö., YILDIZ, I., AKI, E., ÖZKAN, S., KAYNAK, F., "Synthesis, Antimicrobial Activity, Pharmacophore Analysis of Some New 2-(Substitutedphenyl/ benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles", European Journal of Medicinal Chemistry, 43(11), 2568-2578, (2008). doi:10.1016/j.ejmech.2007.12.019 [tüm metin]
  • 63
    OKSUZOGLU, E., TEKINER-GULBAS, B., ALPER, S., TEMIZ-ARPACI, O., ERTAN, T., YILDIZ, I., DIRIL, N., SENER-AKI, E., YALCIN, I., "Some Benzoxazoles and Benzimidazoles as DNA Topoisomerase I and II Inhibitors", Journal of Enzyme Inhibition and Medicinal Chemistry, 23(1), 37-42, (2008). DOI: 10.1080/14756360701342516 [tüm metin]
  • 62
    OKSUZOGLU, E., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., EROGLU, H., SEN, G., ALPER, S., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "A Study on the Genotoxic Activities of Some New Benzoxazoles", Medicinal Chemistry Research, 16, 1–14, (2007). DOI 10.1007/s00044-007-9005-z [tüm metin]
  • 61
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., OKSUZOGLU, E., EROGLU, H., YILDIZ, I., DIRIL, N., AKI-SENER, E., YALCIN, I., "QSAR of Genotoxic Active Benzazoles", SAR and QSAR in Environmental Research, 18(3-4), 251–263, (2007). DOI: 10.1080/10629360701303966 [tüm metin]
  • 60
    MARTINS, M., SCHELZ, Z., MARTINS, A., MOLNAR, J., HAJÖS, G., RIEDL, Z., VIVEIROS, M., YALCIN, I., AKI-SENER, E., AMARAL, L., "In Vitro and Ex Vivo Activity of Thioridazine Derivatives against Mycobacterium tuberculosis", International Journal of Antimicrobial Agents, 29, 338–340, (2007). doi:10.1016/j.ijantimicag.2006.10.013[tüm metin]
  • 59
    ERTAN, T., YILDIZ, I., OZKAN, S., TEMIZ-ARPACI, O., KAYNAK, F., YALCIN, I., AKI-SENER, E., ABBASOGLU, U., "Synthesis and Biological Evaluation of New n-(2-Hydroxy-4(or 5)-nitro/ aminophenyl)benzamides and Phenylacetamides as Antimicrobial Agents", Bioorganic and Medicinal Chemistry, 15, 2032-2044, (2007). doi:10.1016/j.bmc.2006.12.035 [tüm metin]
  • 58
    KAROLAK-WOJCIECHOWSKA, J., MROZEK, A., CZYLKOWSKI, R., TEKINER-GULBAS, B., AKI-SENER, E., YALCIN, I., "Five-membered heterocycles. Part IV: Impact of heteroatom on benzazole aromaticity", Journal of Molecular Structure, 839, 125-131, (2007). doi:10.1016/j.molstruc.2006.11.023 [tüm metin]
  • 57
    TEMİZ-ARPACI, Ö., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALCIN, İ., "3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method", QSAR and Molecular Modelling in Rational Design of Bioactive Molecules, Istanbul-Turkey, September 5-10, 2004, AKI-ŞENER, E., YALÇIN, İ. (Eds.), Başkent Publishing, Ankara, pp.396-398, (2006). [tüm metin]
  • 56
    ALPER-HAYTA, S., AKI-SENER, E., TEKINER-GULBAS, B., YILDIZ, I., TEMIZ-ARPACI, O., YALCIN, I., ALTANLAR, N., “Synthesis, Antimicrobial Activity and QSARs of New Benzoxazine-3-ones”, Eur. J. Med. Chem., 41(12), 1398-1404, (2006). [tüm metin]
  • 55
    TEMIZ-ARPACI, O., COBAN, T., TEKINER-GULBAS, B., CAN-EKE, B., YILDIZ, İ., AKI-SENER, E., YALCIN, I., ISCAN, M., “A Study on the Antioxidant Activities of Some New Benzazole Derivatives”, Acta Biol. Hungarica, 57(2), 201-209, (2006). [tüm metin]
  • 54
    TEKINER-GULBAS, B., TEMIZ-ARPACI, O., YILDIZ, I., AKI-SENER, E., YALCIN, I., “3D-QSAR Study on Heterocyclic Topoisomerase II Inhibitors using CoMSIA”, SAR and QSAR in Enviromental Research, 17(2), 121-132, (2006). [tüm metin]
  • 53
    LAGE, H., AKI-SENER, E., YALCIN, I., “High Antineoplastic Activity of New Heterocyclic Compounds in Cancer Cells with Resistance against Classical DNA Topoisomerase II Targeting Drugs”, Int. J. Cancer, 119, 213-220, (2006). [tüm metin]
  • 52
    VARGA, A., AKI-SENER, E., YALCIN, I., TEMIZ-ARPACI, O., TEKINER-GULBAS, B., CHEREPNEV, G., MOLNAR, J., “Induction of Apoptosis and Necrosis by Resistance Modifiers Benzazoles and Benzoxazines on Tumour Cell Line Mouse Lymphoma L5718 Mdr+cells”, In vivo, 19, 1087-1092, (2005). [tüm metin]
  • 51
    TEMIZ-ARPACI, O., TEKINER-GULBAS, B., YILDIZ, İ., AKI-ŞENER, E., YALÇIN, İ., “3D-QSAR Analysis on Benzazole Derivatives as Eukaryotic Topoisomerase II Inhibitors by using Comparative Molecular Field Analysis Method”, Bioorganic&Medicinal Chemistry, 13, 6354–6359, (2005). [tüm metin]
  • 50
    TEMİZ-ARPACI, O., ÖZDEMİR, A., YALÇIN, İ., YILDIZ, İ., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 5-[2-(Morpholin-4-yl)acetamido] and/or 5-[2-(4-Substituted piperazin-1-yl)acetamido]-2-(p-substituted phenyl)benzoxazoles", Arch. Pharm. Chem. Life Sci., 338, 105-111, (2005). [tüm metin]
  • 49
    YILDIZ-OREN, İ., TEKINER-GULBAŞ, B., TEMİZ-ARPACI, Ö., YALÇIN, İ., AKI-SENER, E., "Quantitative Structure-Activity Relationships using Comparative Molecular Field Analysis Studies on 2-(p-Substitutedbenzyl)-5-(substituted carbonylamino)benzaoxazoles as Antibacterial Agents against Staphylococcus aureus", Asian Journal of Chemistry, 16(3-4), 1359-1366, (2004). [tüm metin]
  • 48
    ÖREN-YILDIZ, İ., TEKİNER-GULBAŞ, B., YALÇIN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of New 2-[p-Substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles”, Arch. Pharm. Pharm. Med. Chem, 337, 402-410, (2004). [tüm metin]
  • 47
    PLEMPER, R.K., ERLANDSON, K.J., LAKDAWALA, A.S., SUN, A., PRUSSIA, A., BOONSOMBAT, J., AKI-ŞENER, E., YALÇIN, İ., YILDIZ, İ., TEMİZ-ARPACI, Ö., TEKİNER, B. P., LIOTTA, D., SNYDER, J.P., COMPANS, R.W., “A Target Site for Template-Based Design of Measles Virus Entry Inhibitors”, PNAS, 101(15), 5628-5633, (2004). [tüm metin]
  • 46
    ÖREN-YILDIZ, İ., YALÇIN, İ., AKI-ŞENER, E., UCARTURK, N., “Synthesis and Structure-Activity Relationships of New Antimicrobial Active Multisubstituted Benzazole Derivatives”, European Journal of Medicinal Chemistry, 39, 291-298, (2004). [tüm metin]
  • 45
    PINAR, A., YURDAKUL, P., YILDIZ, İ., TEMİZ-ARPACI, Ö., AÇAN, N.L., AKI-ŞENER, E., YALÇIN, İ.,”Some Fused Heterocyclic Compounds as Eukaryotic Topoisomerase II Inhibitors”, Biochemical and Biophysical Research Communications, 317, 670-674, (2004). [tüm metin]
  • 44
    YILDIZ-ÖREN, i., AKI-ŞENER, E., ERTAŞ, C., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological activity of Some Substituted N-(2-hydroxy-4-nitrophenyl)benzamides and phenylacetamides as Possible Metabolites of Antimicrobial Active Benzoxazoles”, Turk J Chem., 28, 441-449, (2004). [tüm metin]
  • 43
    YALÇIN, İ., TEKİNER, B.P., ÖREN-YILDIZ, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2,6,7-trisubstituted-2H-3,4-dihydro-1,4-benzoxazin-3-one Derivatives”, Indian Journal of Chemistry, 42B, 905-909, (2003). [tüm metin]
  • 42
    AKBAY, A., ÖREN, İ., TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., “Synthesis and HIV-1 Reverse Transcriptase Inhibitor Activity of Some 2,5,6-Substituted Benzoxazole, Benzimidazole, Benzothiazole and Oxazolo(4,5-b)pyridine Derivatives”, Arzneim-Forsch./Drug Res., 53(4), 266-271, (2003). [tüm metin]
  • 41
    AKBAY-YARPUZLU, A., YILDIZ, İ., TEMIZ-ARPACI, Ö., KARAGENÇ, N., AKI-ŞENER, E., YALÇIN, İ., “Adenosine Deaminase Inhibitor Activity of Some Benzoxazole, Benzimidazole, and Oxazolo(4,5-b)pyridine Derivatives”, XIII. Biotecnological Congress Proceedings Book, Çanakkale, 21-26, (2003).
  • 40
    TEMIZ-ARPACI, Ö., OREN, İ., AKI-ŞENER, E., YALÇIN, İ., TEKINER, B., “QSARs of Some Antibacterial Active Benzoxazoles against B. subtilis”, J. Fac. Pharm., Ankara, 31(2), 73-81, (2002). [tüm metin]
  • 39
    TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some 2-(p-Substituted-phenyl)benzoxazol-5-yl-arylcarboxamides”, Arch. Pharm. Pharm. Med. Chem, 6, 283-288, (2002). [tüm metin]
  • 38
    TEMİZ-ARPACI, Ö., AKI-ŞENER, E., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel N-[2-(p-Substitutedphenyl)-5-benzoxazolyl]-cyclohexyl carboxamide, -cyclohexyl acetamide and –cyclohexyl propionamide Derivatives”, Il Farmaco, 57, 771-775, (2002). [tüm metin]
  • 37
    AKI-ŞENER, E., BİNGÖL, K.K., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some N-(2-hydroxy-4-substitutedphenyl)benzamides, phenylacetamides and furamides as the Possible Metabolites of Antimicrobial Active Benzoxazoles”, Il Farmaco, 57, 451-456, (2002). [tüm metin]
  • 36
    CZYLKOWSKI, R., KAROLAK-WOJCIECHOWSKA, J., MROZEK, A., YALÇIN, İ., ŞENER, E.A., “Spacer Conformation in Biologically Active Molecules. Part I. Structure and Conformational Preferences of 2-Substituted-benzoxazoles”, J. Mol. Structure, 598(2-3), 197-204, (2001). [tüm metin]
  • 35
    AKI-ŞENER, E., BİNGÖL, K.K., ÖREN, İ., TEMİZ-ARPACI, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some N-(o-hydroxyphenyl)benzamides and phenylacetamides as the Possible Metabolites of Antimicrobial Active Benzoxazoles, Part II.”, Il Farmaco, 55, 469-476, (2000). [tüm metin]
  • 34
    YALÇIN, İ., ÖREN, İ., TEMİZ, Ö., ŞENER, E.A., “QSARs of Some Novel Isosteric Heterocyclics with Antifungal Activity”, Acta Biochimica Polonica, 47(2), 481-486, (2000). [tüm metin]
  • 33
    AKI-ŞENER, E., ARPACI-TEMİZ, Ö., YALÇIN, İ., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel 5-Benzamido- and 5-phenylacetamido- substituted 2-phenylbenzoxazole Derivatives”, Il Farmaco, 55, 397-405, (2000). [tüm metin]
  • 32
    MROZEK, A., TRZEZWINSKA, H., KAROLAK-WOICIECHOWSKA, J., YALÇIN, İ., ŞENER, E., “Molecular Structure of 5-Chloro-2-(p-t-butylphenyl)benzoxazole. Relation Between Structure and Antimicrobial Activity of 2,5-Disubstituted Benzoxazoles”, Polish J. Chem., 73, 625-633, (1999). [tüm metin]
  • 31
    MROZEK, A., KAROLAK-WOICIECHOWSKA, J., YALÇIN, İ., ŞENER, E., “Crystal Structure of 2-(2'-Cyclohexyl)ethyl benzimidazole, C15H20N2”, Z. Kristallogr. NCS, 214, 181-182, (1999). [tüm metin]
  • 30
    ÖREN, İ., TEMİZ, Ö., YALÇIN, İ., ŞENER, E., ALTANLAR, N., “Synthesis and Antimicrobial Activity of Some Novel 2, 5- and/or 6-Substituted Benzoxazole and Benzimidazole Derivatives”, European Journal of Pharmaceutical Sciences, 7(2), 153-160, (1999). [tüm metin]
  • 29
    TEMİZ, Ö., ÖREN, İ., ŞENER, E., YALÇIN, İ., UÇARTÜRK, N., “Synthesis and Microbiological Activity of Some Novel 5- or 6-Methyl-2-(2,4-disubstituted phenyl)benzoxazole Derivatives”, Il Farmaco, 53, 337-341, (1998). [tüm metin]
  • 28
    YALÇIN, İ., KAYMAKÇIOĞLU, B.K., ÖREN, İ., ŞENER, E., TEMİZ, Ö., AKIN, A., ALTANLAR, N., “Synthesis and Microbiological Activity of Some Novel N-(2-Hydroxyl-5-substitutedphenyl)benzacetamides, Phenoxyacetamides and Thiophenoxyacetamides as The Possible Metabolites of Antimicrobial Active Benzoxazoles”, Il Farmaco, 52(11), 685-689, (1997). [tüm metin]
  • 27
    ÖREN, İ., TEMİZ, Ö., YALÇIN, İ., ŞENER, E., AKIN, A., UÇARTÜRK, N., “Synthesis and Microbiological Activity of 5(or 6)-Methyl-2-substituted Benzoxazole and Benzimidazole Derivatives”, Arzneim-Forsch./Drug Res., 47(II), 1393-1397, (1997). [tüm metin]
  • 26
    ŞENER, E., YALÇIN, İ., TEMİZ, Ö., ÖREN, İ., AKIN, A., UÇARTÜRK, N., "Synthesis and Structure-Activity Relationships of Some 2,5-Disubstitured Benzoxazoles and Benzimidazoles as Antimicrobial Agents", Il Farmaco, 52(2), 99-103, (1997). [tüm metin]
  • 25
    TÜRKER, L., GÜLLÜ, M., YALÇIN, İ., ŞENER, E., ÇELEBİ, N., "Relationships Between Theoretically Calculated LUMO Energies and Cathodic Peak Potentials of Some 2-Benzylbenzoxazole Derivatives", Bulletin Soc Chim. Belg, 105(6), 303-306, (1996). [tüm metin]
  • 24
    ŞENER, E., TEMİZ, Ö., ÖREN, İ., YALÇIN, İ., AKIN, A., UÇARTÜRK, N., "Synthesis, Antibacterial Activity and QSARs of Some 5-Substituted-2-(p-substitutedbenzyl)benzoxazoles using the Free-Wilson Analysis", J. Fac. Pharm. Ankara, 24(1), 10-20, (1995). [tüm metin]
  • 23
    YALÇIN, İ., ŞENER, E., ÖREN, İ., TEMİZ, Ö., "Determination of the Activity Contributions of Some Novel Isosteric Heterocyclics against an Enteric Gram-negative Rod using the Free-Wilson Analysis" In Sans, F., Giraldo, J. and Manaut, F. (Eds.) QSAR and Molecular Modelling:Concepts, Computational Tools and Biological Applications. Prous, Barcelona, pp. 147-151 (1995).
  • 22
    GÜLLÜ, M., YALÇIN, İ., ŞENER, E., TÜRKER, L., ÇELEBİ, N., AKBULUT, U., "Relationships between Cathodic Peak Potentials and Theoretically Calculated LUMO Energies of Some 2-Phenybenzoxazole Derivatives", Bulletin Soc. Chim. Belg, 103(3), 87-90, (1994). [tüm metin]
  • 21
    ŞENER, E., TURGUT, H., YALÇIN, İ., ÖREN, İ., TÜRKER, L., ÇELEBİ, N., AKIN, A., "Synthesis, Microbiological Activity and Structure-Activity Relationships of Some Antimicrobial 5-Substituted-2-(3-pyridyl)benzoxazoles using Quantum Chemical Calculations", International Journal of Pharmaceutics, 110, 109-115, (1994). [tüm metin]
  • 20
    YALÇIN, İ., ŞENER, E., ÖREN, İ., "QSAR of Some Antibacterial Active Isosteric Heterocyclic Compounds against an Enterobacter" In Wermuth, C. G. (Ed.) Trends in QSAR and Molecular Modelling 92. Escom, Leiden, pp. 570-572 (1993).
  • 19
    YALÇIN, İ., ŞENER, E., "QSARs of Some Novel Antibacterial Benzimidazoles, Benzoxazoles and Oxazolopyridines against an Enteric Gram-negative Rod K. pneumoniae", International Journal of Pharmaceutics, 98, 1-8, (1993). [tüm metin]
  • 18
    YALÇIN, İ., ÖREN, İ., ŞENER, E., AKIN, A., UÇARTÜRK, N., "The Synthesis and the Structure- Activity Relationships of Some Substituted Benzoxazoles, Oxazolo(4,5-b)pyridines, benzothiazoles and benzimidazoles as Antimicrobial Agents", European Journal of Medicinal Chemistry, 27, 401-406, (1992). [tüm metin]
  • 17
    TÜRKER, L., ŞENER, E., YALÇIN, İ., AKBULUT, U., KAYALIDERE, İ., "QSAR of Some Antifungal Active Benzoxazoles using the Quantum Chemical Parameters", Scientica Pharmaceutica, 58, 107-113, (1990).[tüm metin]
  • 16
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., ÖZDEN, S., AKIN, A., "Synthesis and Microbiological Activity of 5-Metyl-2-(p-substitutedphenyl)benzoxazoles", European Journal of Medicinal Chemistry, 25, 705-708, (1990). [tüm metin]
  • 15
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Antibacterial Activity of 2-Phenyloxazolo(4,5-b)pyridine Derivatives against Gram(-) Bacteria and the Quantitative Structure-Activity Relationships", FABAD J. Pharm. Sci., 13(3), 441-449, (1988).[tüm metin]
  • 14
    ŞENER, E., YALÇIN, İ., AKIN, A., NOYANALPAN, N., "Antifungal Activity of 2-Benzylbenzoxazole Derivatives and QSAR’s by Free-Wilson Analysis", J. Fac. Pharm. Gazi, 4(1), 1-9, (1987). [tüm metin]
  • 13
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "Synthesis and Antimicrobial Activities of 5-Amino-2-(p-substitutedphenyl)benzoxazole Derivativies", Doğa TUJ. Med. and Pharm., 11(3), 391-396, (1987). [tüm metin]
  • 12
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Antifungal Activity of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives against Candida albicans and the Quantitative Structure-Activity Relationships", FABAD J. Pharm. Sci., 12(4), 281-288, (1987). [tüm metin]
  • 11
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antibacterial Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Gram (+) Bacteria using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", FABAD J. Pharm. Sci., 12(1), 48-55, (1987). [tüm metin]
  • 10
    YALÇIN, İ., ŞENER, E., ÖZDEN, S., AKIN, A., YILDIZ, S., "The Antibacterial Activity of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives against Streptococcus faecalis and Staphylococcus aureus and the Quantitative Structure-Activity Relationships", FABAD j. Pharm. Sci., 12(3), 213-221, (1987). [in Turkish] [tüm metin]
  • 9
    ÖZDEN, S., ÖZDEN, T., ŞENER, E., YALÇIN, İ., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 5-Nitro-2-(p-Substitutedphenyl)benzoxazoles-III", FABAD J. Pharm. Sci., 12(1), 39-47, (1987). [in Turkish] [tüm metin]
  • 8
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antibacterial Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Gram (-) Bacteria using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", J. Fac. Pharm. Gazi, 3(2), 133-142, (1986). [tüm metin]
  • 7
    NOYANALPAN, N., ŞENER, E., "The Quantitative Structure-Activity Relationships of AntiHistaminic Active 5-Substituted-2-(p-Substitutedbenzyl)benzoxazole Derivatives", J. Fac. Pharm. Gazi, 3(1), 1-11, (1986). [tüm metin]
  • 6
    ŞENER, E., YALÇIN, İ., ÖZDEN, S., ÖZDEN, T., "The Quantitative Structure-Activity Relationships of Antifungal Active 2-(p-Substitutedphenyl)benzoxazole Derivatives against Candida albicans using the Combinations of Some Hydrophobic, Electronic and Steric Paramaters", J. Fac. Pharm. Ankara, 16(1), 24-30, (1986) [tüm metin]
  • 5
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., ÖZDEN, S., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 5-Chloro-2-(p-Substitutedphenyl)benzoxazoles-II", FABAD J. Pharm. Sci., 11(4), 257-269, (1986). [in Turkish] [tüm metin]
  • 4
    ŞENER, E., ÖZDEN, S., YALÇIN, İ., ÖZDEN, T., AKIN, A., YILDIZ, S., "The Synthesis, Structure Elucidations and Microbiological Activities of 2-(p-Substitutedphenyl)benzoxazoles-I", FABAD J. Pharm. Sci., 11(3), 190-202, (1986). [in Turkish] [tüm metin]
  • 3
    NOYANALPAN, N., ŞENER, E., "The Synthesis, Structure Elucidations and Antihistaminic Activities of 5-Nitro-2-(p-substitutedbenzyl)benzoxazole Derivatives", FABAD J. Pharm. Sci., 11(2), 111-119, (1986). [in Turkish] [tüm metin]
  • 2
    YALÇIN, İ., ŞENER, E., ÖZDEN, T., "The Synthesis and Structure Elucidations of 2-(p-Substitutedphenyl)oxazolo(4,5-b)pyridine Derivatives", J. Fac. Pharm. Ankara, 15(1), 69-78, (1985). [in Turkish][tüm metin]
  • 1
    NOYANALPAN, N., ŞENER, E., "The Synthesis, Structure Elucidations and Antihistaminic Activities of 2-(p-Substitutedbenzyl)benzoxazole Derivatives", FABAD J. Pharm. Sci., 10(4), 275-286, (1985). [in Turkish] [tüm metin]