PROF.DR. ASUMAN SUNGUROĞLU    
Name : ASUMAN
Surname : SUNGUROĞLU
E-Mail : asungur@medicine.ankara.edu.tr
Phone Number : +90 312 5958188
Title : PROF.DR.
Unit : FACULTY OF MEDICINE
Department : BASIC SCIENCE DEPARTMENTS
Personal Information

NAME & SURNAME             :ASUMAN SUNGUROGLU

ACADEMIC TITLE                  :PROFESSOR

DEPARTMENT                       :MEDICAL BIOLOGY

DATE OF BIRTH (YEAR):1963

BUSINESS ADDRESS           : ANKARA UNIVERSITY FACULTY OF MEDICINE

 

ACADEMIC CAREER:

Education

1980-1985 Hacettepe University, Faculty of Sciences,  Biologist Degree

1986-1988 MSc.degree Hacettepe University, Oncology Enstitute, Tumor Biology and Immunology, Ankara

1988-1992 PhD degree, Ankara University, Heath of Sciences Enstitutes, Medical Biology Department, Faculty of Medicine, Ankara

 

Carreer / Employment

1986-1992 Assistant of Medical Biology Department, Faculty of Medicine, Ankara University.

1992- Assistant Professor of Medical Biology Department, Faculty of Medicine, Ankara University.

1997-2003 Associate Professor of Medical Biology Department, Faculty of Medicine, Ankara University.

2003- Professor of Medical Biology Department, Faculty of Medicine, Ankara University.

2003- Chairman and Head, Department of Medical Biology Department, Faculty of Medicine, Ankara University.

 

ADMINISTRATIVE  RESPONSIBILITIES:

 

2004-Ankara University Faculty of Medicine Social Committee

2012-Head of Ankara University Social Committee

 

INTERNATIONAL EXPERIENCE:

2006-University Hospital of Welsh-Cardiff ENGLAND

 

CURRENT PROFESSIONAL MEMBERSHIPS:

European Association of Cancer Research

Society for Medicinal Plant Research

Society of European Human Genetics

Turkish Hematology Society

Turkish Biochemistry Society

 

AWARDS AND GRANTS:

Tubitak  Publishment Awards

 

RESEARCH AREA

Cancer Genetics and Cytogenetics, Cancer Biology: Epigenetics, methylation, apoptosis, stem   cells, cell  signalling, gene expression

 

INTERNATIONAL PUBLICATIONS:

1.Investigation of CD133 and CD24 as candidate azoospermia markers and their relationship with spermatogenesis defects. Yukselten Y, Aydos OSE, Sunguroglu A, Aydos K.

Gene. 2019 May 1. pii: S0378-1119(19)30379-8. doi: 10.1016/j.gene.2019.04.028. [Epub ahead of print]

2.ADAMTS1 and ADAMTS5 metalloproteases produced by Sertoli cells: a potential diagnostic marker in azoospermia. Aydos OS, Yukselten Y, Ozkavukcu S, Sunguroglu A, Aydos K. Syst Biol Reprod Med. 2019 Feb;65(1):29-38. doi: 10.1080/19396368.2018.1467512.

3.Expression analysis of Akirin-2, NFκB-p65 and β-catenin proteins in imatinib resistance of chronic myeloid leukemia. Karabay AZ, Koc A, Ozkan T, Hekmatshoar Y, Altinok Gunes B, Sunguroglu A, Buyukbingol Z, Atalay A, Aktan F. Hematology. 2018 Dec;23(10):765-770. doi: 10.1080/10245332.2018.1488795. Epub 2018 Jun 26.

4. Characterization of imatinib-resistant K562 cell line displaying resistance mechanisms.

Hekmatshoar Y, Ozkan T, Altinok Gunes B, Bozkurt S, Karadag A, Karabay AZ, Sunguroglu A. Cell Mol Biol (Noisy-le-grand). 2018 May 15;64(6):23-30.

5.Fusion and reprogramming of human cardiomyocytes with human mesenchymal stem cells. Karadag, A.; Ozkan, T.; Sunguroglu, A. FEBS OPEN BIO   Volume: 8   Supplement: 1   Pages: 155-156   Meeting Abstract: P.05-025-M   Published: JUL 2018

6. Modulation of ER stress related genes by MSM in HCT-116 colon cancer cells

Hekmatshoar, Y.; Ozkan, T.; Karabay, A. Z.; et al. FEBS OPEN BIO   Volume: 8   Supplement: 1   Pages: 346-347   Meeting Abstract: P.10-165-W   Published: JUL 2018

7. Novel effect of azithromycin in imatinib-resistant CML cells. Ozkan, T.; Hekmatshoar, Y.; Karabay, A. Z.; et al. FEBS OPEN BIO   Volume: 8   Supplement: 1   Pages: 346-346   Meeting Abstract: P.10-164-T   Published: JUL 20185.

8. Determination of the Apoptotic Effect and Molecular Docking of Benzamide Derivative XT5 in K562 Cells. Ozkan T, Hekmatshoar Y, Ertan-Bolelli T, Hidayat AN, Beksac M, Aki-Yalcin E, Yalcin I, Sunguroglu A. Anticancer Agents Med Chem. 2018;18(11):1521-1530. doi: 10.2174/1871520618666171229222534.

9. Genetic Polymorphisms in PRM1, PRM2, and YBX2 Genes are Associated with Male Factor Infertility. Aydos OSE, Hekmatshoar Y, Altınok B, Özkan T, Şakirağaoğlu O, Karadağ A, Kaplan F, Ilgaz S, Taşpınar M, Yükselen I, Sunguroğlu A, Aydos K. Genet Test Mol Biomarkers. 2018 Jan;22(1):55-61. doi: 10.1089/gtmb.2017.0040. Epub 2017 Dec 11.

10.Incomplete Antibodies May Reduce ABO Cross-match Incompatibility. A Pilot Study. Özen M, Yılmaz S, Özkan T, Özer Y, Pekel AA, Sunguroğlu A, Gürman G, Arslan Ö.Turk J Haematol. 2017 May 23. doi: 10.4274/tjh.2016.0504. [Epub ahead of print]

11. Apoptotic effects of some tetrahydronaphthalene derivatives on K562 human chronic myelogenous leukemia cell line. Koç A, Ozkan T, Karabay AZ, Hekmatshoar Y, Gurkan-Alp AS, Aktan F, Buyukbingol Z, Sunguroglu A, Buyukbingol E. Anticancer Agents Med Chem. 2017 Apr 12. doi: 10.2174/1871521409666170412122811. [Epub ahead of print]

12. A differential cytokine expression profile before and after rFSH treatment in Sertoli cell cultures of men with nonobstructive azoospermia

By: Heidargholizadeh, S.; Aydos, S. E.; Yukselten, Y.; et al. ANDROLOGIA   Volume: 49   Issue: 4     Article Number: e12647   Published: MAY 2017

13. Lomeguatrib, a O-6-Methylguanine-DNA-Methyltransferase (MGMT) Inhibitor, Induces DNA Damage Induced Apoptosis By Targeting Double-Strand DNA Repair in Multiple Myeloma By: Yildiz, Dilara Akcora; Ozkan, Tulin; Yukselten, Yunus; et al. Conference: 58th Annual Meeting and Exposition of the American-Society-of-ematology Location: San Diego, CADate: DEC03-06,2016.Sponsor(s): Amer Soc Hematol BLOOD   Volume: 128   Issue: 22   Meeting Abstract: 2103   Published: DEC 2 2016

14. Role of ADAMTS1 and ADAMTS5 in male infertility

By: Aydos, S. E.; Yukselten, Y.; Sunguroglu, A.; et al.

ANDROLOGIA   Volume: 48   Issue: 10   Pages: 1113-1119   Published: DEC 2016

12. Impact of rFSH treatment on Sertoli cell cytokine expression

By: Aydos, S. Erdogan; Heidargholizadeh, S.; Yukselten, Y.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
Sponsor(s): 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 80-80   Meeting Abstract: ST04044003  Published: SEP 2016

16. Gene expression profile of protamines in male infertility

By: Aydos, S.; Altinok, B.; Ozkan, T.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
Sponsor(s): 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 135-136   Meeting Abstract: P02091-018  Published: SEP 2016

17. Comparative genome wide gene expression analyses of primary MSC and MSC lines

By: Akpinar, A. E.; Karadag, A.; Cubukcuoglu, G. Deniz; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 142-142   Meeting Abstract: P03011-014  Published: SEP 2016

18. Effects of MLH1 and MSH2 expression on imatinib resistance in CML

By: Hekmatshoar, Y.; Ozkan, T.; Altinok, B.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 162-162   Meeting Abstract: P05011-036  Published: SEP 2016

19. A benzamide derivative XT5 and imatinib combination induced apoptosis in Imatinib resistant K562 cell line

By: Ozkan, T.; Hekmatshoar, Y.; Bolelli, T. Ertan; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 162-162   Meeting Abstract: P05011-035  Published: SEP 2016

20. Role of apoptotic markers for determination of postmortem interval (PMI)

By: Yildirim, E. F.; Yukselten, Y.; Sunguroglu, A.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 220-220   Meeting Abstract: P02022-045  Published: SEP 2016

21. Role of extracellular matrix proteases for determination of post mortem interval

By: Parlakgorur, M.; Avci, A.; Sunguroglu, A.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 285-285   Meeting Abstract: P02075-005  Published: SEP 2016

22. TNFRSF21 and TNFSF7 are possible markers to target CD133+GBM stem cells

By: Ozkanca, S.; Yukselten, Y.; Bal, M. G.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 303-303   Meeting Abstract: P05033-019  Published: SEP 2016

23. Tie2/TEK: a potential biomarker for targeting glioblastoma stem cells

By: Yukselten, Y.; Bal, M. G.; Ozkanca, S.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 304-305   Meeting Abstract: P05033-023  Published: SEP 2016

24. Genome-wide analysis of hypoxic stress response in human cardiomyocytes

By: Karadag, A.; Ozkan, T.; Akpinar, A. E.; et al.

Conference: 41st FEBS Congress on Molecular and Systems Biology for a Better Life Location: Kusadasi, TURKEYDate: SEP 03-08, 2016 
FEBS JOURNAL   Volume: 283   Special Issue: SI   Supplement: 1   Pages: 310-311   Meeting Abstract: P06025-004  Published: SEP 2016

25. Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells

By: Karabay, Arzu Zeynep; Koc, Asli; Ozkan, Tulin; et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES   Volume: 17   Issue: 7     Article Number: 1123   Published: JUL 2016

26. The role of the collagen type 1 alpha 1 gene polymorphism in the prediction of osteoporosis and fracture risk in Turkish postmenopausal women

By: Saban, Ilknur; Gok, Haydar; Aydos, Sena; et al.

TURKIYE FIZIKSEL TIP VE REHABILITASYON DERGISI-TURKISH JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION   Volume: 62   Issue: 1   Pages: 1-8   Published: MAR 2016

27. Analysis of the correlation between sperm DNA integrity and conventional semen parameters in infertile men

By: Aydos, Oya Sena; Yukselten, Yunus; Kaplan, Fuat; et al.

TURKISH JOURNAL OF UROLOGY   Volume: 41   Issue: 4   Pages: 191-197   Published: DEC 2015

28. Impact of follicle-stimulating hormone receptor variants in female infertility

By: Ilgaz, Nermin Seda; Aydos, Oya Sena Erdogan; Karadag, Aynur; et al.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS   Volume: 32   Issue: 11   Pages: 1659-1668   Published: NOV 2015

29. The investigation of genetic analysis of genes encoding sperm nuclear proteins with the effects on fertility in infertile men

By: Aydos, O. S.; Altinok, B.; Ozkan, T.; et al.

Conference: 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life Location: Berlin, GERMANY Date: JUL 04-09, 2015 
FEBS JOURNAL   Volume: 282   Special Issue: SI   Supplement: 1   Pages: 64-65   Meeting Abstract: P02-036  Published: JUL 2015

30. Association of Contrin (YBX2) 187T > C and 1095+16A > G single nucleotide polymorphisms with male factor infertility

By: Hekmatshoar, Y.; Aydos, O. S.; Kaplan, F.; et al.

Conference: 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life Location: Berlin, GERMANY Date: JUL 04-09, 2015 
FEBS JOURNAL   Volume: 282   Special Issue: SI   Supplement: 1   Pages: 65-65   Meeting Abstract: P02-038  Published: JUL 2015

31. Hydrogen peroxide-induced oxidative damage in human mononuclear leukocyte: the anti-genotoxic effects of H. Perforatum extract on DNA damage

By: Aktepe, N.; Keskin, C.; Yukselten, Y.; et al.

Conference: 40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life Location: Berlin, GERMANY Date: JUL 04-09, 2015 
FEBS JOURNAL   Volume: 282   Special Issue: SI   Supplement: 1   Pages: 128-128   Meeting Abstract: P10-065  Published: JUL 2015

32. Synthesis and anticancer effects of some novel 2-(4-phenoxyphenyl)-1H-benzimidazole derivatives on K562 cell line

By: Gurkan-Alp, A. Selen; Goker, Hakan; Alp, Mehmet; et al.

ARCHIVES OF PHARMACAL RESEARCH   Volume: 38   Issue: 5   Pages: 650-658   Published: MAY 2015

33. The Role of IL33 in Glioblastoma Multiforme

By: Demircan, Kadir; Yukselten, Yunus; Bal, Merve; et al.

FASEB JOURNAL   Volume: 29   Supplement: 1   Meeting Abstract: LB142   Published: APR 2015

34. Isolation of Human Glioblastoma Multiforme Primary Cells and analysis of CD133(+)

By: Yukselten, Yunus; Yildiz, Dilara Akcora; Demircan, Kadir; et al.

FASEB JOURNAL   Volume: 29   Supplement: 1   Meeting Abstract: LB135   Published: APR 2015

35. Synthesis and antiproliferative evaluation of novel 5-(4-methylpiperazin-1-yl)-2-phenyl-1H-benzimidazole derivatives

By: Alp, Mehmet; Gurkan-Alp, A. Selen; Ozkan, Tulin; et al.

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES   Volume: 70   Issue: 3-4  Pages: 79-85   Published: MAR 2015

36.Association of MDR1 C3435T and C1236T single nucleotide polymorphisms with male factor infertility

By: Aydos, S. E.; Karadag, A.; Ozkan, T.; et al.

GENETICS AND MOLECULAR RESEARCH   Volume: 14   Issue: 2   Pages: 6330-6339   Published: 2015

37. Methylation analysis of the DAPK1 gene in imatinib-resistant chronic myeloid leukemia patients

By: Celik, Selcen; Akcora, Dilara; Ozkan, Tulin; et al.

ONCOLOGY LETTERS   Volume: 9   Issue: 1   Pages: 399-404   Published: JAN 2015

38. Methylsulfonylmethane modulates apoptosis of LPS/IFN-gamma-activated RAW 264.7 macrophage-like cells by targeting p53, Bax, Bcl-2, cytochrome c and PARP proteins

By: Karabay, Arzu Z.; Aktan, Fugen; Sunguroglu, Asuman; et al.

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY   Volume: 36   Issue: 6   Pages: 379-389   Published: DEC 2014

39. Cell fusion following cardiomyocyte and mesenchymal stem cell co-culture and functional evaluation of cellular changes

By: Karadag, A.; Deniz, G. Cubukcuoglu; Dastouri, M.; et al.

Conference: FEBS EMBO 2014 Conference Location: Paris, FRANCE Date: AUG 30-SEP 04, 2014  EMBO FEBS JOURNAL   Volume: 281   Special Issue: SI   Supplement: 1   Pages: 220-220   Meeting Abstract: SUN-452  Published: SEP 2014

40. Effects of OCT4, SOX2 and NANOG expression on imatinib resistance in CML

By: Hekmatshoar, Y.; Ozkan, T.; Zaim, B. Altinok; et al.

Conference: FEBS EMBO 2014 Conference Location: Paris, FRANCE Date: AUG 30-SEP 04, 2014 EMBO FEBS JOURNAL   Volume: 281   Special Issue: SI   Supplement: 1   Pages: 224-224   Meeting Abstract: SUN-465  Published: SEP 2014

41. Genome wide investigation of genes regulated by Beta-catenin in AML

By: Ozkan, T.; Zaim, B. Altinok; Karadag, A.; et al.

Conference: FEBS EMBO 2014 Conference Location: Paris, FRANCE Date: AUG 30-SEP 04, 2014 EMBO FEBS JOURNAL   Volume: 281   Special Issue: SI   Supplement: 1   Pages: 468-468   Meeting Abstract: TUE-110  Published: SEP 2014

42. Identification of genes in Wnt signaling pathway with DNA microarray analysis in acute myeloid leukemia

By: Zaim, B. Altinok; Ozkan, T.; Karadag, A.; et al.

Conference: FEBS EMBO 2014 Conference Location: Paris, FRANCE Date: AUG 30-SEP 04, 2014 EMBO FEBS JOURNAL   Volume: 281   Special Issue: SI   Supplement: 1   Pages: 474-474   Meeting Abstract: TUE-126  Published: SEP 2014

43. Investigation of the Taspine's antiproliferative, antiangiogenic and apoptotic effects on U118 and U87 glioblastoma multiforme cell lines

By: Sharifi, S. S.; Aydos, S.; Ozkan, T.; et al.

Conference: FEBS EMBO 2014 Conference Location: Paris, FRANCE Date: AUG 30-SEP 04, 2014 EMBO FEBS JOURNAL   Volume: 281   Special Issue: SI   Supplement: 1   Pages: 480-481   Meeting Abstract: TUE-145  Published: SEP 2014

44. Synthesis and cytotoxic evaluation of novel N-substituted amidino-1-hydroxybenzimidazole derivatives

By: Alp, Mehmet; Goker, Hakan; Ozkan, Tulin; et al.

ARCHIVES OF PHARMACAL RESEARCH   Volume: 37   Issue: 5   Pages: 580-587   Published: MAY 2014

45. Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination

By: Ugur, Hasan Caglar; Taspinar, Mehmet; Ilgaz, Seda; et al.

MOLECULAR BIOLOGY REPORTS   Volume: 41   Issue: 2   Pages: 697-703   Published: FEB 2014

46. A Preliminary Investigation on the Presence of Calcifying Nanoparticles in the Breast Tumor

By: Ozkal-Baydin, Pinar; Gocmen, Sedef J.; Erdemli, Esra; et al.

UHOD-ULUSLARARASI HEMATOLOJI-ONKOLOJI DERGISI   Volume: 24   Issue: 1   Pages: 17-22   Published: 2014

47. Effects of gamma irradiation on cell cycle, apoptosis and telomerase activity in p53 wild-type and deficient HCT116 colon cancer cell lines

By: Halacli, Sevil Oskay; Canpinar, Hande; Cimen, Eren; et al.

ONCOLOGY LETTERS   Volume: 6   Issue: 3   Pages: 807-810   Published: SEP 2013

48. Peripheral blood mononuclear cell microchimerism in Turkish female patients with systemic sclerosis

By: Sahin, Ali; Ozkan, Tulin; Turkcapar, Nuran; et al.

MODERN RHEUMATOLOGY   Volume: 24   Issue: 1   Pages: 97-105   Published: JAN 2014

49. The roles of epigenetic modifications of proapoptotic BID and BIM genes in imatinib-resistant chronic myeloid leukemia cells

By: Bozkurt, Sureyya; Ozkan, Tulin; Ozmen, Fusun; et al.

HEMATOLOGY   Volume: 18   Issue: 4   Pages: 217-223   Published: JUL 2013

50. Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells

By: Taspinar, Mehmet; Ilgaz, Seda; Ozdemir, Mevci; et al.

TUMOR BIOLOGY   Volume: 34   Issue: 3   Pages: 1935-1947   Published: JUN 2013

51. The effect of CYP1A1, GSTT1 and GSTM1 polymorphisms on the risk of lung cancer: A case-control study

By: Atinkaya, Cansel; Taspinar, Mehmet; Sakiragaoglu, Onur; et al.

HUMAN & EXPERIMENTAL TOXICOLOGY   Volume: 31   Issue: 10   Pages: 1074-1080   Published: OCT 2012

52. Variations in glutathione-S-transferase genes influence risk of chronic myeloid leukemia

By: Oezten, Nur; Sunguroglu, Asuman; Bosland, Maarten C.

HEMATOLOGICAL ONCOLOGY   Volume: 30   Issue: 3   Pages: 150-155   Published: SEP 2012

53. Effects of methylsulfonylmethane on viability of HCT-116 cell line

By: Karabay, A. Z.; Ozkan, T.; Koc, A.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 55-55   Published: SEP 2012

54. Effects of methylprednisolone on DNA methylation in HL-60 AML cells

By: Yukselen, I.; Altinok, B.; Karadag, A.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 495-496   Published: SEP 2012

55. The role of MDR1 C3435T single nucleotide polymorphism in male infertility

By: Karadag, A.; Aydos, S.; Ozkan, T.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 560-561   Published: SEP 2012

56. Investigation of apoptotic and efflux-pump gene expressions in Imatinib resistant CML cell line

By: Sunguroglu, A.; Ozkan, T.; Altinok, B.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 574-574   Published: SEP 2012

57. Effect of methylsulfonylmethane on iNOS gene methylation in macrophages

By: Buyukbingol, Z.; Karabay, A. Z.; Ozkan, T.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 575-576   Published: SEP 2012

58. GSTP1 gene methylation analysis in prostate cancer

By: Ozkan, T.; Gokce, I.; Altinok, B.; et al.

Conference: 22nd IUBMB Congress/37th FEBS Congress Location: Seville, SPAIN Date: SEP 04-09, 2012 IUBMB; FEBS JOURNAL   Volume: 279   Special Issue: SI   Supplement: 1   Pages: 576-576   Published: SEP 2012

59. MDR1 gene polymorphisms may be associated with Behcet's disease and its colchicum treatment responseBy: Rustemoglu, Aydin; Gul, Ulker; Gumus-Akay, Guvem; et al.

GENE   Volume: 505   Issue: 2   Pages: 333-339   Published: SEP 1 2012

60. Potential genotoxic effect of Re-186-HEDP on human lymphocyte cells: in-vitro evaluation with micronucleus-FISH analysis

By: Ozkal-Baydin, Pinar; Gumus-Akay, Guvem; Varol, Nuray; et al.

NUCLEAR MEDICINE COMMUNICATIONS   Volume: 33   Issue: 4   Pages: 415-421   Published: APR 2012

61. Impact of Genetic Variations of the CYP1A1, GSTT1, and GSTM1 Genes on the Risk of Coronary Artery Disease. By: Taspinar, Mehmet; Aydos, Sena; Sakiragaoglu, Onur; et al.

DNA AND CELL BIOLOGY   Volume: 31   Issue: 2   Pages: 211-218   Published: FEB 2012

62. Effect of L-carnitine on the synthesis of nitric oxide in RAW 264 center dot 7 murine macrophage cell line

By: Koc, A.; Ozkan, T.; Karabay, A. Z.; et al.

CELL BIOCHEMISTRY AND FUNCTION   Volume: 29   Issue: 8   Pages: 679-685   Published: DEC 2011

63. Effect of Urtica dioica on proliferation of HCT-116 colon cancer cell line

By: Aydos, S.; Avci, A.; Durak, I; et al.

Conference: 59th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-and-Natural-Product-Research Location: Antalya, TURKEY Date: SEP 04-09, 2011 
Sponsor(s): Soc Med Plant & Nat Prod Res

PLANTA MEDICA   Volume: 77   Issue: 12   Pages: 1372-1373   Published: AUG 2011

64. Antiproliferative, apoptotic and antioxidant activities of wheatgrass (Triticum aestivum L.) extract on CML (K562) cell line

By: Aydos, Oya Sena; Avci, Aslihan; Ozkan, Tulin; et al.

TURKISH JOURNAL OF MEDICAL SCIENCES   Volume: 41   Issue: 4   Pages: 657-663   Published: AUG 2011

65. Epigenetic regulation of bim and bid proapoptotic genes by polycomb group proteins in imatinib mesylate resistant and non-resistant chronic myeloid leukemia cell lines

By: Bozkurt, S.; Ozkan, T.; Kansu, E.; et al.

Conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine Location: Torino, ITALY Date: JUN 25-30, 2011 
Federat Soc Biochem & Mol Biol FEBS JOURNAL   Volume: 278   Special Issue: SI   Supplement: 1   Pages: 81-81   Published: JUN 2011

66. Expression of nucleostemin in glioblastoma multiforme tumor cells and its effect on the diagnosis and prognosis

By: Caliskan, E.; Altinok, B.; Ozkan, T.; et al.

Conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine Location: Torino, ITALY Date: JUN 25-30, 2011 
Federat Soc Biochem & Mol Biol FEBS JOURNAL   Volume: 278   Special Issue: SI   Supplement: 1   Pages: 193-194   Published: JUN 2011

67. Detection of NPM1 gene mutations in AML patients in Turkish population

By: Ozturk, G.; Altinok, B.; Ozkan, T.; et al.

Conference: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine Location: Torino, ITALY Date: JUN 25-30, 2011 
Federat Soc Biochem & Mol Biol FEBS JOURNAL   Volume: 278   Special Issue: SI   Supplement: 1   Pages: 212-212   Published: JUN 2011

68. A STUDY OF PARAOXONASE I GENE POLYMORPHISMS WITH THE RISK AND SEVERITY OF NON-SMALL CELL LUNG CANCER (NSCLC) IN TURKISH PATIENTS

By: Ahsan, Fadhil; Sunguroglu, Asuman

JOURNAL OF THORACIC ONCOLOGY   Volume: 6   Issue: 6   Supplement: 2   Pages: S755-S755   Published: JUN 2011

69. Effects of aqueous garlic extract on oxidant/antioxidant status in 32D and 32Dp210 cell lines

By: Avci, Aslihan; Sunguroglu, Asuman; Erguder, Imge B.; et al. TURKISH JOURNAL OF MEDICAL SCIENCES   Volume: 40   Issue: 6   Pages: 881-888   Published: DEC 2010

70. Effects of antioxidants on post-thawed bovine sperm and oxidative stress parameters: Antioxidants protect DNA integrity against cryodamage

By: Bucak, Mustafa Numan; Tuncer, Purhan Barbaros; Sariozkan, Serpil; et al.

CRYOBIOLOGY   Volume: 61   Issue: 3   Pages: 248-253   Published: DEC 2010

71. Effect of methylsulfonylmethane on LPS-IFN-gamma induced RAW 264.7 macrophage apoptosis

By: Karabay, A. Z.; Ozkan, T.; Koc, A.; et al.

Conference: 35th Congress of the Federation-of-European-Biochemical-Societies Location: Gothenburg, SWEDENDate: JUN 26-JUL 01, 2010

FEBS JOURNAL   Volume: 277   Supplement: 1   Pages: 57-57   Published: JUN 2010

72. Effect of L-carnitine on NF-kB activity in lipopolysaccharide stimulated RAW 264.7 macrophage cell By: Koe, A.; Ozkan, T.; Karabay A., Z.; et al. Conference: 35th Congress of the Federation-of-European-Biochemical-Societies Location: Gothenburg, SWEDENDate: JUN 26-JUL 01, 2010 FEBS JOURNAL   Volume: 277   Supplement: 1   Pages: 146-147   Published: JUN 2010

73. Effect of wnt3a or lithium chloride preconditioning on nitric oxide production in RAW264.7 macrophages and K562 leukemic cell line By: Karabay, A. Z.; Ozkan, T.; Koc, A.; et al. Conference: 35th Congress of the Federation-of-European-Biochemical-Societies Location: Gothenburg, SWEDENDate: JUN 26-JUL 01, 2010 FEBS JOURNAL   Volume: 277   Supplement: 1   Pages: 147-148   Published: JUN 2010

74. NF-kappaB activation and complex control of NOS2 gene promoter in K562 imatinib mesylate resistant CML cell line By: Ozkan, T.; Karadag, A.; Altinok, B.; et al.

Conference: 35th Congress of the Federation-of-European-Biochemical-Societies Location: Gothenburg, SWEDENDate: JUN 26-JUL 01, 2010 FEBS JOURNAL   Volume: 277   Supplement: 1   Pages: 147-147   Published: JUN 2010

75. Haplotype-Based Analysis of MDR1/ABCB1 Gene Polymorphisms in a Turkish Population By: Gumus-Akay, Guevem; Rustemoglu, Aydin; Karadag, Aynur; et al.

DNA AND CELL BIOLOGY   Volume: 29   Issue: 2   Pages: 83-90   Published: FEB 2010

76. DNA Copy Number Changes in Gastric Adenocarcinomas: High Resolution-Comparative Genomic Hybridization Study in Turkey By: Gumus-Akay, Guvem; Unal, Ali Ekrem; Elhan, Atilla Halil; et al. ARCHIVES OF MEDICAL RESEARCH   Volume: 40   Issue: 7   Pages: 551-560   Published: OCT 2009

77. Acute myeloid leukemia in Turkish children with Fanconi anemia. One center experience in the period between 1964-1995  By: Gozdasoglu, Sevgi; Ertem, Mehmet; Uysal, Zuemruet; et al. TURKISH JOURNAL OF HEMATOLOGY   Volume: 26   Issue: 3   Pages: 118-122   Published: SEP 2009

78. Association of CYP1A1 and glutathione S-transferase polymorphisms with male factor infertility By: Aydos, Sena Erdogan; Taspinar, Mehmet; Sunguroglu, Asuman; et al. Conference: 6th Annual Meeting of the Mediterranean-Society-for-Reproductive-Medicine Location: Antalya, TURKEY Date: APR 20-23, 2007 Sponsor(s): Mediterranean Soc Reproduct Med

FERTILITY AND STERILITY   Volume: 92   Issue: 2   Pages: 541-547   Published: AUG 2009

79. The effect of LPS incubation periods on nitric oxide levels in RAW 264.7 macrophage cell line By: Akinci, A.; Karabay, A.; Oezkan, T.; et al.

Conference: 34th Congress of the Federation-of-European-Biochemical-Societies Location: Prague, CZECH REPUBLIC Date: JUL 04-09, 2009 
Sponsor(s): Federat European Biochem Soc

FEBS JOURNAL   Volume: 276   Pages: 297-297   Published: JUL 2009

80. Effect of methylsulfonylmethane on proliferation and nitric oxide production in LPS activated RAW 264.7 cells By: Karabay, A. Z.; Akinci, A.; Ozkan, T.; et al.

Conference: 34th Congress of the Federation-of-European-Biochemical-Societies Location: Prague, CZECH REPUBLIC Date: JUL 04-09, 2009 
Sponsor(s): Federat European Biochem Soc FEBS JOURNAL   Volume: 276   Pages: 316-316   Published: JUL 2009

81. Wheatgrass extract affects lipid peroxidation levels in human promyelocytic leukemia cell line HL-60 By: Ozkan, T.; Bakar, F.; Karabay, A. Z.; et al. Conference: 34th Congress of the Federation-of-European-Biochemical-Societies Location: Prague, CZECH REPUBLIC Date: JUL 04-09,2009 Federat European Biochem Soc FEBS JOURNAL   Volume: 276   Pages: 334-334   Published: JUL 2009

82. Effects of MSM (methylsulfonylmethane) on SNP (sodium nitroprusside) and H2O2 (hydrogen peroxide) induced RAW 264.7 macrophages

By: Karabay, Z. A.; Ozkan, T.; Koc, A.; et al. Conference: 57th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-Research-and-Natural-Product  Research Location: Geneva, SWITZERLAND Date: AUG 16-20, 2009 
Soc Medicinal Plant & Nat Prod Res PLANTA MEDICA   Volume: 75   Issue: 9   Pages: 911-911   Published: JUL 2009

83. Wheatgrass extract increases proliferation of RAW 264.7 macrophages induced by hydrogen peroxide (H2O2) or lipopolysaccharide (LPS)

By: Ozkan, T.; Karabay, Z. A.; Koc, A.; et al. Conference: 57th International Congress and Annual Meeting of the Society-for-Medicinal-Plant-Research-and-Natural-Product-Research Location: Geneva, SWITZERLAND Date: AUG 16-20, 2009 
Sponsor(s): Soc Medicinal Plant & Nat Prod Res PLANTA MEDICA   Volume: 75   Issue: 9   Pages: 923-923   Published: JUL 2009

84. EFFECT OF L-CARNITINE ON NO PRODUCTION IN LIPOPOLYSACCHARIDE INDUCED RAW 264.7 CELLS By: Koc, Asli; Karabay, Arzu Z.; Ozka, Tulin; et al.

IUBMB LIFE   Volume: 61   Issue: 3   Pages: 327-327   Published: MAR 2009

85. PLASMA ADA AND PON1-ARYLESTERASE ENZYME ACTIVITIES IN LUNG CANCER PATIENTS By: Gurleyik, Ebru; Taspinar, Mehmet; Oztuna, Derya; et al. IUBMB LIFE   Volume: 61   Issue: 3   Pages: 337-338   Published: MAR 2009

86. PLASMA NITRIC OXIDE LEVELS AND NITRIC OXIDE SYNTHASE ACTIVITY IN LUNG CANCER PATIENTS By: Korkmaz, Sebnem; Gurleyik, Ebru; Taspinar, Mehmet; et al.

IUBMB LIFE   Volume: 61   Issue: 3   Pages: 373-374   Published: MAR 2009

87. WHEATGRASS JUICE REDUCES NITRIC OXIDE PRODUCTION IN LPS INDUCED RAW 264.7 CELLS By: Aydos, Sena; Ozkan, Tulin; Karabay, Arzu Z.; et al.

IUBMB LIFE   Volume: 61   Issue: 3   Pages: 376-376   Published: MAR 2009

88. Effects of Genomic Imbalances on Telomerase Activity in Gastric Cancer: Clues to Telomerase Regulation By: Gumus-Akay, Guvem; Elhan, Atilla Halil; Unal, Ali Ekrem; et al.

Conference: 12th World Congress on Advances in Oncology/10th International Symposium on Molecular MedicineLocation: Hersonissos, GREECE Date: OCT 11-13, 2007

ONCOLOGY RESEARCH   Volume: 17   Issue: 10   Pages: 455-462   Published: 2009

89. Apoptotic effect of wheatgrass (Triticum aestivum L.) extract on Baf3p210 and Baf3p210-T3151 leukemia cell lines By: Altinok, B.; Ozkan, T.; Karadag, A.; et al.

Conference: 7th Joint Meeting of the Association-Francophone-pour-l'Enselgnement-et-la-Recherche-en-Pharmacognosie/American-Society-of-Pharmacognosy/Society-for-Medicinal-Plant-Research/Phytochem-Society-of-Europe/Societa-Italiana-di-Fitochimica : Athens, GREECE Date: AUG03-08,2008 Assoc Francophone Enseignement Rech Pharmacognosie; Amer Soc Pharmacognosy; Soc Medicinal Plant Res; Phytochem Soc Europe; Soc Italiana Fitochim PLANTA MEDICA   Volume: 74   Issue: 9   Pages: 970-970   Published: JUL 2008

90. Effect of wheatgrass (Triticum aestivum L.) on oxidant/antioxidant status in Baf 3p210 and T315i cell lines By: Avci, A.; Gurleyik, E.; Ozkan, T.; et al. Conference: 7th Joint Meeting of the Association-Francophone-pour-l'Enselgnement-et-la-Recherche-en-Pharmacognosie/American-Society-of-Pharmacognosy/Society-for-Medicinal-Plant-Research/Phytochem-Society-of-Europe/Societa-Italiana-di-Fitochimica Location: Athens, GREECE Date: AUG03-08,2008 ,Assoc Francophone Enseignement Rech Pharmacognosie; Amer Soc Pharmacognosy; Soc Medicinal Plant Res; Phytochem Soc Europe; Soc Italiana Fitochim PLANTA MEDICA   Volume: 74   Issue: 9   Pages: 1010-1010   Published: JUL 2008

91. The importance of genetic polymorphisms of phase I and phase II enzymes in the development of atherosclerosis By: Taspinar, M.; Aydos, S.; Comez, O.; et al.

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION   Volume: 38   Issue: 5   Pages: 342-342   Meeting Abstract: KVBD6   Published: MAY 2008

92. By: Taspinar, M.; Comez, O.; Duzen, I. V.; et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION   Volume: 38   Issue: 5   Pages: 355-355   Meeting Abstract: KVBD-45   Published: MAY 2008

93. CYP1A1 GST gene polymorphisms and risk of chronic myeloid leukaemia By: Taspinar, Mehmet; Aydos, Sena Erdogan; Comez, Omer; et al. SWISS MEDICAL WEEKLY   Volume: 138   Issue: 1-2   Pages: 12-17   Published: JAN 12 2008

94. Genotype and allele frequencies of MDR1 gene C1236T polymorphism in a Turkish population By: Gumus-Akay, G.; Rustemoglu, A.; Karadag, A.; et al.

GENETICS AND MOLECULAR RESEARCH   Volume: 7   Issue: 4   Pages: 1193-1199   Published: 2008

95. Antiproliferative and apoptotic effects of wheatgrass (Triticum aestivum L.) extracts on chronic myeloid leukemia (CML) cell line By: Karadag, A.; Ozkan, T.; Altinok, B.; et al. Conference: 55th Annual Congress of the Society-for-Medicinal-Plant-Research Location: Karl Franzens Univ, Graz, AUSTRIA Date: SEP 02-06, 2007 
Sponsor(s): Soc Med Plant Res PLANTA MEDICA   Volume: 73   Issue: 9   Pages: 991-992   Meeting Abstract: P540   Published: AUG 86. 2007

96. Molecular pathogenesis of pancreatic cancer: Review By: Sahin, Fikret; Taspinar, Mehmet; Sunguroglu, Asuman TURKIYE KLINIKLERI TIP BILIMLERI DERGISI   Volume: 27   Issue: 4   Pages: 560-566   Published: AUG 2007

97. Telomerase activity could be used as a marker for neoplastic transformation in gastric adenocarcinoma: but it does not have a prognostic significance By: Gumus-Akay, G.; Unal, A. E.; Bayar, S.; et al. GENETICS AND MOLECULAR RESEARCH   Volume: 6   Issue: 1   Pages: 41-49   Published: 2007

98. Antiproliferative and apoptotic effects of garlic on chronic myeloid leukemia cell line

By: Sunguroglu, A.; Akay, G. G.; Ozkal, P.; et al. Conference: 54th Annual Congress on Medicinal Plant Research Location: Helsinki, FINLAND Date: AUG 29-SEP 02, 2006 Soc Medicinal Plant Res; Univ Helsinki,Fac Pharm PLANTA MEDICA   Volume: 72   Issue: 11   Pages: 1057-1057   Meeting Abstract: P252   Published: SEP 2006

99. Effects of aqueous garlic extract on oxidant/antioxidant status in 32 D and 32 Dp cell lines By: Durak, I; Sunguroglu, A.; Avci, A.; et al. Conference: 54th Annual Congress on Medicinal Plant Research Location: Helsinki, FINLAND Date: AUG 29-SEP 02, 2006  Sponsor(s): Soc Medicinal Plant Res; Univ Helsinki,Fac Pharm PLANTA MEDICA   Volume: 72   Issue: 11   Pages: 1058-1058   Meeting Abstract: P256   Published: SEP 2006

100. D17S30 and TP53 VNTR loci polymorphisms in a Turkish population By: Gumus, G; Rustamov, A; Kadikiran, A; et al. HUMAN BIOLOGY   Volume: 76   Issue: 5   Pages: 785-788   Published: OCT 2004

101. Transfer of BCR/ABL fusion gene to phagocyter cell by apoptotic bodies. By: Pekkurnaz, G; Tukun, A; Elhan, A; et al. Conference: AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics Location: BOSTON, MASSACHUSETTS Date: NOV 17-21,2003 AACR; NCI; EORTC CLINICAL CANCER RESEARCH   Volume: 9   Issue: 16   Supplement: S   Pages: 6167S Part: 2   Published: DEC 1 2003

102. Common fragile sites associated with the breakpoints of chromosomal aberrations in hematologic neoplasms By: Gumus, G; Sunguroglu, A; Tukun, A; et al.

CANCER GENETICS AND CYTOGENETICS   Volume: 133   Issue: 2   Pages: 168-171   Article Number: PII S0165-4608(01)00569-6   Published: MAR 2002

103. Autoimmune hemolytic anemia in Philadelphia positive chronic myeloid leukemia with t(7;14) anomaly after 5 years of interferon alpha treatment By: Koksal, A; Ozatli, D; Haznedaroglu, IC; et al. HAEMATOLOGIA   Volume: 32   Issue: 2   Pages: 163-167   Published: 2002

104. A sex-specific difference in homozygosity for HLA-DR53 in newborns By: Sunguroglu, A; Guc, D; Sipahi, TU; et al. TURKISH JOURNAL OF PEDIATRICS   Volume: 40   Issue: 2   Pages: 211-216   Published: APR-JUN 1998

105. Donor leukocyte infusions for the treatment of leukemia relapse after allogeneic hematopoietic progenitor cell transplantation. By: Gurman, G; Arslan, O; Koc, H; et al.

BLOOD   Volume: 90   Issue: 10   Supplement: 1   Pages: 4452-4452   Part: 2   Published: NOV 15 1997

106. Donor mononuclear cells infusion and alfa interferon administration in relapsed chronic myeloid leukemia patients after allogeneic bone marrow transplantation By: Gurman, G; Koc, H; Akan, H; et al. BLOOD   Volume: 88   Issue: 10   Supplement: 1   Pages: 3800-3800   Part: 2   Published: NOV 15 1996

107. ORBITO-OCULAR GRANULOCYTIC SARCOMA (OOGS) AND ACUTE MYELOBLASTIC-LEUKEMIA (AML) WITH DUPLICATION OF PHILADELPHIA-CHROMOSOME

By: CAVDAR, AO; BOKESOY, I; SUNGUROGLU, A; et al. CANCER GENETICS AND CYTOGENETICS   Volume: 69   Issue: 1   Pages: 38-40   Published: AUG 1993