PROF.DR. BELMA KONUKLUGİL    
Adı : BELMA
Soyadı : KONUKLUGİL
E-posta :
Tel : 203 30 92
Ünvan : PROF.DR.
Birim : ECZACILIK FAKÜLTESİ
Bölüm : ECZACILIK MESLEK BİLİMLERİ BÖLÜMÜ
Kişisel Akademik Bilgiler

Adı:                            Belma

Soyadı:                       Konuklugil

Adres:                        Ankara Üniversitesi

                                   Eczacılık Fakültesi

                                   Farmakognozi Anabilim Dalı

                                   Tandoğan,Ankara,06100

E-posta:                     belma.konuklugil@gmail.com

Tel:                             312-2033092

 

Eğitim:           

Lisans:                       Ankara Üniversitesi, Eczacılık Fakültesi

Yüksek Lisans:         Ankara Üniversitesi, Eczacılık Fakültesi, Farmakognozi

                                   Anabilim Dalı

Doktora:                    University of Nottingham, School of Pharmacy.  –İngiltere

Kazanılan Burslar:

1995 July- October  DFG - Heinrich Heine-Universität, Institut für Entwicklungs- & Molekularbiologie der Pflanzen,Düsseldorf  University, Molecular Biologie.(Almanya).

    1996 -  British Council - Lougbrough University Medicinal and Chemistry Department

                 ( İngiltere)

 

1998-  Nato B2  -  Heinrich Heine-Universität, Institut für Entwicklungs- & Molekularbiologie 

              der Pflanzen, (Almanya).

1999 -DAAD Heinrich Heine-Universität, Institut für Entwicklungs- & Molekularbiologie der 

             Pflanzen, (Almanya). 

2014 DAAD   Pharmaceutical Biology in Düsseldorf University (Almanya). 


Uluslararası ilişkiler

Prof. Peter Proksch, Institut für Pharmazeutische Biologie und Biotechnologie Heinrich-Heine-Universität Düsseldorf, Germany )of the Sponge Group at the University of Duesseldorf

Prof. Anake Kijjoa,Chemistry of the Biomedical Sciences Institute of Abel Salazar (ICBAS), University of Porto, Portugal

Dr. RuAngelie Edrada-Ebel Head, Natural Products Metabolomics Research Group Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyd, England

Ass. Prof.Dr. Yohei Sanasai- Laboratory of Molecular Pharmacognosy,Division of Pharmaceutical Sciences,Graduate School of Medical Science,Kanazawa University,Kakuma-machi, Kanazawa, Ishikawa,Japan

Dr. Moritz Müller, Research Fellow, Centre for Ocean Engineering, Science and Technology
Adjunct Research Fellow, Faculty of Science, Engineering and Technology, Swinburne University of Technology Sarawak Campus (SUTS) Malesia

Çalışma Alanları:

 uçucu yağlar, 

 Flavonoitler, Lİgnanlar 

  Bitki doku kültürü 

*Deniz kaynaklı bioaktif maddeler

*Deniz kaynaklı mantarlardan bioaktif maddeler

*ülkemiz için çok yeni bir konu, ben ve ekibim bu konuda çalışan ilk kişileriz.

 Bazı yayınlar


1-  Konuklugil, B., “Lignans from Linum flavum. var.compactum,” , Biochemical

     Systematics and Ecology, 25(1) 75, 1997.

2-Konuklugil, B., “Lignans from Linum flavum. var.compactum,” , Biochemical

     Systematics and Ecology, 25(1) 75, 1997.

3- Bucar,  F., Ninov, S., Ionkova, I., Kartnig,T., Schubert-Zsilavecz, M., Asenov, I. and Konuklugil, B., “Flavonoids from Phlomis nissolii,” Phytochemistry, 48(3), 573-575, 1998.

4- Konuklugil, B., “Arylteralin lignans from Linum catharticum L.,”Biochemical Systematics

     and Ecology, 26, 795-796, 1998.

5- Konuklugil, B., Schmidt, T.J and Alfermann, A. W., “ Accumulation of aryltetraline lactone lignans in cell suspension cultures of Linum nodiflorum,” Planta Medica, 65, 587, 1999.

6- Konuklugil, B., Schmidt, T. J., and Alfermann, A. W., “Accumulation of lignans in suspension cultures of Linum mucronatum ssp.armenum(Bordz.) Davis,” Z. Naturfosch. 56c: 1164-1165, 2001.

7- Saygı.Ş, Konuklugil,B., Kutsal,O., Uzbay,T., Deniz,G., and Gören,Z., “Assesment of

       therapeutic effect of Inula  heterolepsis Boiss in alcoholic rats,” Ptytotherapy Research,

      17, 683-687, 2003.

8- Koulman, A., and Konuklugil, B.,  “Lignan profile of Linum meletonis,”Biochemical 

       Systematics and Ecology,Vol.32, 91-93, 2004.

9- Kartal, M., Konuklugil, B., Alfermann, A.W., and Indrayanto,G.,“Comparison of

      different extraction methods for the determination of   podophyllotoxin and  6-

      methoxypodophyllotoxin on Linum species,” Journal of Pharmaceutical and Biomedical     Analysis, 35, 441-447, 2004.

10-Koulman, A., Konuklugil,B., Evren, H.,“Aryltetralin lignans from Linum mucronatum Bertol

     ssp. mucronatum, ”  Chemistry of  Natural Compounds, 41, (1) 30-31, 2005.

11- Çoban,T., Konuklugil, B., “Free  radical scavering activity of Linum arboreum  L.”

      Pharmaceutical Biology, 43(4) 370-372, 2005

12-Konuklugil, B., Aryltetralin Lignans from Linum cariense Boiss., Chemistry of  Natural

      Compounds 41, 3,306,-308, 2005

13- Konuklugil, B., and Bahadir Ö., “Phenylpropanoid glycosides from Linum olypicum

        (Linaceae) Turkish Journal of Chemistry,  28,741-744, 2004.

14- Konuklugil, B., Fuss,E., and Alfermann, A. W., “Isolation of the Lignan 6-

          Methoxypodophyllotoxin from Linum boissieri and Biosynthesis of Lignans in this Species”

          Pharmaceutical Biology, 43, 9, 737-739, 2005.

15- Öztürk N., Bozan B., Konuklugil B., “Antioxidant and free radical scavenging activities of Linum olypicum extracts” Anadolu University Journal of Sciences and technology 7,(1) 239-45,2006.

16. İ. Orhan, M. Kartal, Q. Naz, G. Yılmaz, Y. Kan, B. Konuklugil, B. Şener, M.I.   

          Choudhary. “Antioxidant and anticholinesterase evaluation of selected Turkish Salvia

          Species” Food Chemistry, 103, 1247-1254, 2007.

18- S.Aslan, M,Fırat and B.Konuklugil., Essential oil of Cylotrichium longiflorum leblebici,

          Chemistry of Natural Compounds, 6, 601-602,2007.

19- B.Konuklugil, Ionkova,I., N, Vasılev, T.J. Schmidt, J. Windhövel., E. Fuss., A.W.

           Alfermann., “Lignans from Linum species of Section Syllinum nad Linum”

           Natural Products Research, 21(1) 1-6,2007.

20- Y. Kan., A. Gökbulut., M. Kartal., B. Konuklugil., “Development and validation of a LC method fort he analysis of phenolic acid in Türkish Salvia species” Chromatographia,66,147-152,2007.

21  - B. Ozçelık, İ. Orhan, M. Kartal, B. Konuklugil, T. Karaoglu: In vitro testing of antiviral, antibacterial, antifungal effects and cytotoxicity of selected Turkish Phlomis species, Acta Alimentaria, 2010

 22- I. Orhan, M. Kartal, Q. Naz, G. Yilmaz, Y. Kan, B. Konuklugil, B. Şener, M.I.

      Choudhary “Antioxidant and anticholinesterase  evaluation of selected Turkish Salvia

        species” Food Chemistry, 103, 1247-1254, 2007.

23-Kan Y., Gökbulut A., Kartal M., Konuklugil B., Yilmaz G.,”Development and validation

       of a LC method for the analysis of phenolic acids in Türkish Salvia species”

       Chromatographia,66,147-152, 2007.

 

24- Watjen W., Putz,A., Cholou,Y., Kampkötter,A., Totzke,F., Kubbutat,H., Proksch,P.,

      Konuklugil,B., “Hexa-hepta-nonaprenylhydroquinone isolated from Marine sponge  

      Sarcotragus muscarum ve Ircinia fasciculata   induce apoptosis in Hct 116 cells”

      Pharmacy and Pharmacology 61,919-924, 2009.

 

25- S. Aslan H. Evren, B. Konuklugil I. Turkoglu and M. Kartal . “Essential oil composition

      of Achillea teretifolia from Turkey”, Chemistry of Natural Compounds.2, 230-23, 2009.

26- B. Ozçelık, İ. Orhan, M. Kartal, B. Konuklugil, T. Karaoglu. “In vitro testing of antiviral,

      antibacterial   antifungal effects and cytotoxicity of selected Turkish Phlomis species”, Acta

     Alimentaria, 39, 109-115, 2010,

27 - Nihal Aktaş, Bülent Gözcelioğlu, WEn-Han, Lin, Belma Konuklugil  “Avarone  and avarol from the marine sponge Dysidea avara Schmidt from  Marmara coast of Turkey” Fabad 35(3), 119-123, 2010.

28- Bülent Gözcelioğlu, Rob Van Soest, Peter Proksch, Belma Konuklugil,  “Contrubition to

      the knowledge of the Demosponlae ( Porifera) fauna of Turkey”, Zollogy in the Middle

      Esat 54, 149-152,2011.

29-  İlkay Erdoğan, Berrin Özçelik, Belma Konuklugil, Annika Putz,Ülkü Gökçen Kaban and  

        Peter Proksch   “Bioactivity screening of the selected Turkish marine sponges and three

        compounds from Agelas oroides”, Records of Natural Products 6:4356-367 2012.

 

30- Bousetla A, Konuklugil B, Bouacida S, Zellagui A, Rhouati S, Akkal S “Phytochemical study of

     Algerian Foeniculum vulgare Mill (Apiaceae)”  Der Pharmacia Lettre, 5 (5), 305-307, 2013.

31- Bousetla A, M. Kürkçüoğlu,Konuklugil B, H.K.C. Başer, Rouati,S, “Composition of esential oil from    

     Bunium incrassatum from Algeria” Chemistry of  Natural  Compounds, 50(4) 2014.

32-Aktaş N, Genç Y, Gözcelioğlu B, Konuklugil ,  and  Ş, Harput “ Radical Scavenging Activities of  Different Marine Sponge Extracts Mediterranean,  Coast”,  Records of Natural      Products  Vol. 7: 2, 96-104, 2013.

33- Aktaş N, Gözcelioğlu B, Konuklugil B, “Detection of Some Secondary Metabolites from Turkish Marine Sponges Collected in Kemer”, Fabad  36,129-136, 2011(print 2013)

 34- AktaşN, Gözcelioğlu B, , Lin W, Konuklugil B, “ Avarone  and avarol from the marine sponge Dysidea

           avara Schmidt from  Marmara coast of Turkey” Fabad, 35(3), 119-123, 2010.( print 2013)

35- Gözcelioğlu B, Konuklugil B,  Qualitative Detection of Some Secondary Metabolites from Three Turkish Marine  Sponges, Fabad, 37,( 2), 2012 (print2015).

36-  Gao Shang, Li-Hia-Hua, Belma Konuklugil, Lıu Hong-bing, “Study on Bromopyrrole alkaloids from marine sponges Axinalla verrucosa and their immunogical activity in vitro” Chinese Journal of Marine drugs, 34(2) 1-4, (2015).

37-Bülent  Gözcelioğlu, Rob VAN SOEST, Belinda ALVAREZ, Belma KONUKLUGİL, “New species of sponges (Porifera, Demospongiae) from Turkey  coast”, Turkish Journal of  Zoology, 39,555-559,(2015)

38-Huiqin Chen  , Nihal Aktas , , Belma Konuklugil  , Attila Mándi  , Georgios Daletos  , Wenhan Lin  , Haofu Dai  , Tibor Kurtán  , Peter Proksch “ A new fusarielin analogue from Penicillium sp. isolated from the Mediterranean sponge Ircinia oros” Tetrahedron Letters 56, 5317–5320, (2015)

 

 


 Projeler

1-      Bitirilen projeler

a-      Ulusal ve yöneticisi olduğum projeler

3-“Türkiyetede yetişen bitki türlerinden doku kültürü yolu ile podofilotoksin eldesi”   DPT Projesi (2002-2005) 2001-K-120-240

4- “Doku kültürü yolu ile podofilotoksin ve rosmarinik asit eldesi  Ankara Üniversitesi Biyoteknoloji Enstitüsü” (2001-2004)2002-K-120-130-2

5-“Doku Kültürü Yoluyla Podofilotoksin ve Rosmarinik Asit Eldesi” Ankara Üniversitesi Biyoteknoloji Enstitüsü Araştırma Projesi 2001-K-120-240)

 6- “Linum flavum ssp. scabrinerve Kallus ve Süspansiyon Kültürü ile Podofilotoksin eldesi” Ankara Üniversitesi Biyoteknoloji Enstitüsü Projesi 2001K 120-240( 149)

7- “Linum olypicum Bitkisi Üzerinde Ariltetralin ve diğer grub Lignan bileşiklerinin

 Araştırılması”. Ankara Üniversitesi Bilimsel araştırma Projesi. 2002K-08-03

  b- Uluslararası ve yönetici olduğum projeler

1-“Türkiyede yetişen Linum türlerinden bitki doku kültürü ile ariltetralin lignan  eldesi”  Almanya(Jülich)-TÜBİTAK(2000- 2005)

2- “Türkiye denizlerinde yetişen süngelerdeki  ve süngerlerde bulunan mantarlardaki bioaktif doğal ürünler”SBAG-Julich (104S409)( 2006-2009

2-      Devam eden projeler

a- Ulusal ve yöneticisi olduğum projeler

BAP Projesi :  Türkiye Denizlerindeki Sünger ve Diğer Kaynaklardan Biyoaktif Doğal Etken

Maddelerin Eldesi

 

b- Uluslararası ve yönetici olduğum projeler

 Avrupa Birliği 7. çerçeve programı- IRSES, "Bioactive Compounds from Turkish Marine Macro Organisms and Associated Fungi for EU Industries" 2013-

Tübitak –CNR ( Italy)   Chemical and ecological study of the Turkish coasts benthic invertebrates,   Coordinator, 2014-

Tübitak –BMBF (Almanya)