Name : ÜLKÜ
E-Mail :
Phone Number : 03122033435
Title : PROF.DR.
Personal Information





Name                         : Ülkü Mehmetoğlu

Date of birth              : 5 September 1954

Place of birth             : Bafra, TURKEY

Sex                             : Female

Marital status            : Married, 2 Children

e-mail                         :



B.Sc. and M.Sc.         : Chemical Engineering, Hacettepe University, Ankara, Turkey,


Ph.D.                          : Chemical Engineering, Hacettepe University, Ankara, Turkey,




June 1977-October 1984                    : Teaching and Research Assistantship, Chemical

                                                 Engineering Department, Hacettepe University,

             Ankara, Turkey.


October1984-October 1985               :Ph.D., Teaching and Research Assistantship,

                                                            Chemical Engineering Department, Hacettepe

                                                            University, Ankara, Turkey.


October 1985 - October 1989                        : Assistant.Prof., Chemical Engineering

  Department, Ankara  University, Ankara, Turkey.


October 1989  -July 1998                   : Associate Prof., Chemical Engineering

   Department, Ankara University, Ankara, Turkey.


September 1993 - May 1994              : Visiting Scientists, Chemical Engineering

   Department.,  Pennsylvania State University,

   Pennsylvania, USA.


July 1998-                                           : Prof., Chemical Engineering Department, Ankara

                                                              University, Ankara, Turkey.




 Prof., Chemical Engineering Department, Engineering Faculty, Ankara University, Tandoga,, Ankara, Turkey.





M.Sc. Thesis


1-Sevilay Gülşen, “Ethyl alcohol production with free and immobilized Z.mobilis ”,  1988.

2- Mümin Hacımusalar, “Determination of the effective diffusion coefficients in calcium alginate and k-carrageenan gels using moment analysis method”, 1992.

3-Hamdi Kapucu, “Solvent selection in extractive ethanol fermentation”,  1995.

4-Nurcan Tik, “Extractive lactic acid fermentation”, 1996,.

5-Ayten Ateş, ““Extractive citric acid fermentation”, 1997.

6- Dilek Erbay, “Production of Capsidiol in suspended cell cultures of  Capsicum annuum L.”, 1998.

7. Emine Kahya, “Reactive extraction of lactic acid from fermentation media”, 1999.

8. Nursel Gülsoy, " Biotransformation of 3-methyl butanol to 3-methyl butyric acid", 2000.

9. Çiğdem Babaarslan, "Bioremediation of petroleum hydrocarbons", 2001

10. Devrim Çelik, "Biotransformation of 2- phenyl ethanol to phenyl acetaldehyde in a liquid- two phase system”, 2001.

11. Yahya Köseali, “Enantioselective production of ( R )-Benzoin by lipase catalyzed trnsesterification reaction”, 2005

  12. Özlem  Aydoğan, “  In-situ Aspartic acid production and separation using reverse miselle system “ 2005.

13. Fatma Karadeniz,” Kinetic resolution of racemic 1- phenyl 1- propoanol with lipase catalyzed esterification reactions”.

14. Rahime Songür,”Biocatalytic production of enantiomerically pure benzoin from racemic benzoin acetate “, 2009.

15. Pınar Ak, “Biocatalytic deracemisation of racemic 1-phenylethanol”, (continuing).

16. Günay Baydar, “


Ph.D. Thesis


1-Afife Güvenç, “Extraction of Ethanol from Fermentation Broth Using Supercritical  CO2 ”, 1997.

2-Emine Bayraktar, “Investigation of the effect of axial mixing in three phase packed bed bioreactors and application of results to citric acid production process with immobilized A.niger”,  1998.

3-Hamdi Kapucu, “Phenyl acetaldahyde production from phenyl ethanol by biotransformation”, 2000.

4. Tarık Abuhamed, “ Bidegradation of benzene, toluene and phenol in aliquid-two phase system”,  2002.

5. Çiğdem Babaarslan, “Enantioselective production of (R)-Benzoin by biotransfotmation , 2008.

6. Özlem Aydogan, “Production of enantiomerically pure 1-phenylethanol using immobilized L.kefir in a packed –bed bioreactor “, 2012.

7. Hilal  Çelik,” Production of  enantiomerically pure 1-phenylethanol by asymmetric reduction with  vegetable catalyst” (continuing ).

8- Rahime Songür, “ Steroselective reduction of haloketones for production of enantimerically pure  halohydrin  precursor of (S)- propranolol”, (continuing).

9- Ayşe İyigün,”Kinetic resolution of racemic propranolol”, (continuing).




Undergraduate and Graduate:


1- Industrial Chemistry I (Hacettepe University)

2- Industrial Chemistry II (Hacettepe University)

3- Inorganic Technology (Hacettepe University)

4- Heat Transfer (Ankara University)

5- Chemical Reaction Engineering (Ankara University)

6- Thermodynamic (Ankara University)

7- Chemical Engineering Thermodynamic (Ankara University)

8-  Biochemical Engineering Fundamentals (Ankara University)

9- Chemical Engineering Laboratory I (Ankara University)

10- Chemical Engineering Laboratory II (Ankara University)

11- Reactor Design (Ankara University)

12- Process Design I (Ankara University)

13- Process Design II (Ankara University)

14. Biotransformation Processes (Graduate, Ankara University)

15- Instrumental Analysis  (Ankara University)

16- Mathematics  for Chemical Engineering (Ankara University)

17- Advanced Reaction Engineering (Graduate, Ankara University)

18- Biochemical Production with Plant Cells (Graduate, Ankara University)

19. Biological Waste-Water Treatment (Ankara University)

20. Research Technics I and II (Ankara University)

21. Biotechnological Seminers (Graduate, Ankara University)

22. Principles of Biotechnologicl Technics (Graduate, Ankara University)



1. Gülşen, S., Mehmetoğlu, Ü., “Ethanol Production by Immobilized Z. mobilis in a Packed Reactor and Effect of CO2 on Column Performance”, Chem. Biochem. Eng. Q.   ( Biotechnology Citation Index ), 2, 4, 227-229, 1988.

2. Mehmetoğlu, Ü., “Effective Diffusion Coefficient of Sucrose in Calcium Alginate Gel”, Enzyme and Microbiol Technology ( SCI ), 12, 124-126, 1990.          

3. Mehmetoğlu, Ü., Çiçek, S., Koçak, Ç. “Dynamics of a Column Reactor Fermenting Glucose via Immobilized Z.mobilis to Produce Ethyl Alcohol”, Chem.  Biochem. Eng. Q. ( SCI ), 7, 2, 97-100, 1993.         

4. Hacımusalar, M., Mehmetoğlu, Ü., “Determination of the Effective Diffusion Coefficients of Glucose and Ethanol in Calcium Alginate Gel by the Moment Analysis Method”, Chemical Engineering Science ( SCI ), 50, 18, 3001-3004, 1995. 

5. Mehmetoğlu, Ü., Ateş S., Berber, R., “Oxygen Diffusivity in Calcium Alginate Gel Beads Containing G.suboxydans”, Artifical Cells, Blood Substitutes, Immobilization Biotechnology, International Journal ( SCI ), 2, 14, 80-85, 1996.

6. Ateş, S., Mehmetoğlu, Ü., “ A New Method for Immobilization of b- galactosidase and its Utilaziation in a Plug Flow Reactor”, Process Biochemistry ( SCI ), 32, 5, 422-425,1997. 

7. Mehmetoğlu, Ü., Curtis, W. R., “Effects of Abiotic Inducers on Sesquiterpene Synthesis in Hairy Root and Cell Suspension Cultures of H. muticus” Applied Biochemistry and Biotechnology ( SCI ), 67/1, 83-89, 1997. 

8. Güvenç, A., Mehmetoğlu, Ü., Çalımlı, A., “ Supercritical CO2 Extraction of Ethanol from Fermentation Broth in a Semicontinuous System “, J. Supercritical Fluids ( SCI ), 13, 325-329, 1998.

9.   Kapucu, H., Mehmetoğlu, Ü. “Strategies for Reducing Solvent Toxicity in Ethanol Fermentation”, Applied Biochemistry and Biotechnology ( SCI ), 22, 1-8, 1998. 

10. Kapucu,N,.A.Güvenç, Ü.Mehmetoğlu, and A.Çalımlı, 1999. Reactive extraction of organic acids by supercritical CO2, Reviews in Chemical Engineering (SCI ), 15, 4, 233-243

11. Bayraktar,E., B.Çiçek, Ü.Mehmetoğlu, 1999. Mathematical modelling of a packed bed bioreactor for the citric acid production, Reviews in Chemical Engineering ( SCI ), 15, 4, 279-292. 

12. Kapucu, H. and Mehmetoğlu, Ü., 1999. The effects of bioprocess parameters on the yield in extractive ethanol fermentation, Reviews in Chemical Engineering ( SCI ), 15, 4, 307-318. 

13. A.Güvenç, Ü.Mehmetoğlu, A.Çalımlı, 1999. Supercritical CO2 extraction of ethanol, Turkish Journal of Chemistry  ( SCI ), 23(3), p.285-291. 

14. Kapucu, H., Gülsoy, N.,and Mehmetoğlu, Ü., 2000. Disruption and protein release kinetics by ultrasonication of Acetobacter peroxydans cells, Biochemical Engineering Journal ( SCI ), 5, 1, 57-62.

15. Bayraktar E, Ü. Mehmetoğlu, “Production of Citric Acid Using Immobilized     Conidia of Aspergillus niger”, Applied Biochemistry and Biotechonology ( SCI) , 87, 2, 117-125 (2000).

 16. Bayraktar, E., Ü. Mehmetoğlu, “Back Mixing and Liquid Hold-up Up-flow      Packed Bed Bioreactor, Chemical Engineering Communications ( SCI ) , 185, 125-140 (2001).

17.Tik N., Bayraktar and Ü. Mehmetoğlu, “In-situ Reactive Extraction of Lactic Acid from fermentation Media” J.Chem. Technol. Biotechnol. (SCI ) , 76, 764-768 (2001).

18. Kahya E.,. Bayraktar and Ü. Mehmetoğlu, “Optimization of Process Parameters for the Reactive Lactic Acid Extraction”, Turkish Journal of Chemistry ( SCI ) , 25, 223-230 (2001).

19. Koparan, A., Güvenç, A., Kapucu, N., Mehmetoğlu, Ü. and Çalımlı, A., Separation Process of Citric Acid with tertiary Amines/ Diluents in Supercritical CO2, Turkish Journal of Chemistry ( SCI ) ,25 (4):477-484 (2001) .

20. Kılıç,M., E. Bayraktar, S.Ateş, Ü. Mehmetoglu, “Investigation of Extractive Citric Acid fermentation Using Response-surface Methodology”, Process Biochemistry (SCI) ,37, 759-767 (2002).

21. Güvenç, A., Kapucu, N. and Mehmetoğlu, Ü., 2002. “The Production of Isoamyl Acetate Using Immobilized Lipases in Solvent-free System”, Process Biochemistry (SCI), 38,379-386. 

22. Ateş, S., Dingil, N, Bayraktar, E. and Mehmetoğlu, Ü, 2002. " Enhancemen of Citric Acid Production Using Silicon Oil by Immobilized and Freely Suspended Aspergillus niger" Biochemistry (SCI),38, 433-436

23. Kapucu,N., Guvenç,A., Kapucu,H., Mehmetoğlu,Ü. and Çalımlı,A., 2003. “Lipase Catalyzed Synthesis of Oleyl Oleate : Optimization by Response Surface Methodology” , Chemical Engineering Communications (SCI), 190, No:5-8, 779-796.

24. Döker,O. Bayraktar,E., Mehmetoğlu,Ü. and Çalmlı,A., “Production of Iron-Cobalt Compound Nanoparticles using Reverse Micellar System”, Rev. Adv. Mater. Sci. 5, 34-40, (2003). (SCI) 

25. Guvenç,A., Kapucu,N., Bayraktar,E. and Mehmetoğlu,Ü. 2003. Optimization of The Enzymatic Production of Isoamyl Acetate with Novozym 435 from Candida antarctica, Chemical Engineering Communications (SCI), 190, No:5-8, 948-961.

 26. Abuhamed, T., Bayraktar, E., Mehmetoğlu, T., Mehmetoğlu, Ü., 2003. "Substrate Interactions during the Biodegradation of Benzene, Toluene, and Phenol Mixtures", Process Biochemistry ( SCI ), 39, 27-35.

27. Babaarslan, Ç., Abuhamed, T., Tekeli, A., Mehmetoğlu, T., Mehmetoğlu, Ü., 2003." Biodegradation of BTEX Compounds by a Mixed Culture Obtained from Petroleum Formation Water", Energy Sources ( SCI ), 25, 7, 733-742.

28. Çelik,D., Bayraktar,E.  And Mehmetoğlu,Ü. 2003.“Biotransformation of 2-Phenylethanol to Phenylacetaldehyde In A Two-Phase Fed-Batch System”, Biochemical Engineering Journal (SCI) , 17, 5-13. 

29. Güvenç, A., Mehmetoğlu, T., Mehmetoğlu, Ü., 2004. " Effect of Operational Parameters and Ultrasonic Pretreatment on Supercritical Extraction of Diesel Oil from Soil", Energy Sources ( SCI ), 26, 77-82. 

30. Abuhamed, T, Bayraktar, E, Mehmetoğlu, T. and Mehmetoğlu, Ü, 2004. “ The  Biodegradation of  Benzene, Toluene and Phenol in a Two-phase System”,   Biochemical Engineering Journal (SCI) , 19, 137-14. 

31.  Abuhamed, T, Bayraktar, E, Mehmetoğlu, T. and Mehmetoğlu, Ü, ,  2004.“ Kinetics  Model for Growth of Pseudomonas putida F1 During Benzene, Toluene and Phenol Biodegradation”,   Process Biochemistry (SCI)  ,39, 983-988. 

32. Onur Döker, Uğur Salgın, İnci Şanal, Ülkü Mehmetoğlu and Ayla Çalımlı, 2004. Modeling of extraction of ß-carotene from apricot bagasse using supercritical CO2 in packed bed extractor, The Journal of Supercritical Fluids (SCI) , 28/2/11-19 . 

33. Sanal, IS, Güvenç A., Salgin, Çalımlı, A., Mehmetoğlu, Ü., Recycling of Apricot Pomace by Supercritical CO2 Extraction, The Journal of Supercritical Fluids (SCI), 32 (1-3):221-230 ,2004. 

34. Salgın, U, Ustün, AS., Çalımlı, A., Mehmetoğlu, Ü.,2005, Supercritical CO2 extraction of accumulated capsidiol from biotic elicitor activated C. annum L. fruit tissues, Journal of Chemical Technology and Biotechnology (SCI), 80 (2):124-132 ,2005. 

35. Özkal, SG, Yener, ME, Salgın U,  Mehmetoğlu, Ü., 2005, Response surfaces of hazelnut oil yield in superciritical carbon dioksite, European Food Research and Technology (SCI) , 220 (1):74-78 ,2005.

36. Dovyap,Z., Bayraktar, E. and Mehmetoğlu,Ü. Amino Acid Extractıon and Mass Transfer Rate in the Reverse Micelle System, Enzyme and Microbial Technology (SCI) , 38, 557-562, 2006.

 37. Tokçaer,Z., Bayraktar, E., Mehmetoğlu,Ü., Özcengiz, G. and Alaeddinoğlu, N. G., Response Surface Optimization of Antidipteran Delta-endotoxin Production by Bacillus thuringiensis subsp. israelensis HD 500, Process Biochemistry (SCI) , 41, 350-355, 2006.

38. Ateş S,  Cortenlioglu E, Bayraktar, E. and Mehmetoğlu,Ü. Production of L-DOPA from Tyrosinase  Immobilized in  Cu-Alginate  Gel, Enzyme and Microbial Technology, 40 (SCI) , 683-687 (2007). 

39. A. Güvenç, N. Kapucu, H. Kapucu, Ö.Aydoğan, Ü. Mehmetoğlu, 2007. “Enzymatic Esterification of Isoamyl Alcohol Obtained from Fusel Oil: Optimization by Response Surface Methodolgy”, Enzyme and Microbial Technology, 40 (SCI) , 778 - 785.

40. Aydoğan Ö., Bayraktar E., Mehmetoğlu Ü, Parlaktuna M., Mehmetoğlu T, 2007 “Production of L-aspartic acid by biotransformation and it’s recovery using reverse micelle and gas hydrate methods” Biocatalysis and Biotransformation

(SCI), 25(5):365-372. 

41. Bayraktar E, Kocapiçak Ö, Mehmetoğlu Ü, Parlaktuna M, Mehmetoğlu T.

Recovery Of Amino Acid From Reverse Micellar Solution by Gas Hydrate.

 Chemical Engineering Research and Design, 86:209-213, (2008). (SCI) 

42. Aydoğan Ö., Bayraktar E., Mehmetoğlu Ü, Kaeding T, Zeng A P. Selection

 en optimization of an aqueous two-phase systemfor the recovery of1,3-

propandiol from fermentation broth. Engineering in Life Sciences, 10(2) 121-

129 (2010).(SCI) 

43. Karadeniz F., Bayraktar, E. and Mehmetoğlu,Ü. Kinetic Resolution of Racemic 1-Phenyl 1-Propanol by Lipase Catalyzed Enantioselective       Esterification Reaction, Artificial Cells, Blood Substitutes, and Biotechnology, 38, 288-293 (2010). 

            44. Songür R. Lurçi B., Bayraktar, E., Mehmetoğlu,Ü. and Demir A.S.           Enantioselective Production of Benzoin from Benzoin Acetate via Kinetic        Resolution and Deracemization using Rhizopus oryzae. Artificial Cells, Blood   Substitutes, and Biotechnology, (2010).

            45. T. Artan, H. T. Gümüşdere, A. Güvenç, G. Dönmez, Ü. Mehmetoğlu,

2010. “Decolorization of Textile Azo Dyes by Ultrasonication and Microbial

 Removal”, Desalination, 255, 154-158.


46. Aydoğan Ö., Bayraktar, E., Mehmetoğlu, Ü., ‘Asymmetric Bioreduction of

Acetophenone Using κ-carrageenan Immobilized Lactobacillus kefir cells in a Packed Bed Reactor’, Molecular Catalysis B: Enzymatic, Accepted.