ASSOC.PROF.DR. ÖZGE ÜLKER    
Name : ÖZGE
Surname : ÜLKER
E-Mail : oulker@pharmacy.ankara.edu.tr
Phone Number : 203 31 22
Title : ASSOC.PROF.DR.
Unit : FACULTY OF PHARMACY
Department :
Personal Information

NAME: Ozge Ulker
DATE OF BIRTH: 13.06.1979

CURRENT POSITION: Research Assistant

AFFILIATION: Ankara University, Faculty of Pharmacy, Department of Toxicology, Ankara,Turkey

EDUCATION:

PhD degree: Ankara University Faculty of Pharmacy Department of Toxicology, 2010, “Estimation of Relative Contact Allergenic Potency of the Chemicals by Using Non-Radioactive Local Lymph Node Assay and Comparison with the Patch Test Results”  Supervisor: Prof. Dr. Asuman Karakaya
      
Master’s degree: Ankara University, Faculty of Pharmacy, Department of Toxicology, 2004, “The Role of  Pro-inflammatory Cytokines and Antioxidant Enzymes in Coal Workers’ Pneumoconiosis and Disease Clinical Severity”, Supervisor: Prof. Dr. Asuman Karakaya

Undergraduate degree:Ankara University, Faculty of Pharmacy, 2001

AREAS OF INTEREST: Immunotoxicology, occupational toxicology, genetic toxicology, in vitro and alternative toxicity tests

PROJECTS: 

The role of cytokines and cytokine gene polymorphism in development and progression of coal workers’ pneumoconiosis. Supported by Ankara University Research Fund, Project number: 2003–08-03-036, 
Position: Researcher

Investigation on incidence and levels of ochratoxin A (OTA) in human urine samples collected from different region of Turkey by immunoaffinity column clean-up and high performance liquid chromatography. Supported by The Scientific and Technological Research Council of Turkey, Project Number: 105S412
Position: Researcher

Estimation of Relative Contact Allergenic potency of the Chemicals by using Non-Radioactive Local Lymph Node Assay and Comparison with the Patch Test Results Supported by  The Scientific and Technological Research Council of Turkey , Project Number: 107S365 (Doctorate Project)
Position: Researcher 
      
Investigation of antioxidant effect of boric acid in some cell cultures in vitro. Supported by Ankara University Research Fund, Project number: 12B3336007
Position: Project manager


PUBLICATIONS 

1. Yucesoy B., Cemiloglu O., Chronic lung diseases and  cytokines. Sendrom, 15(10): 95-101, 2003.
2. Ulker C.O., Yucesoy B., Durucu M., Karakaya A., Neopterin as a marker for immune system activation in coal workers’ pneumoconiosis, Toxicology and Industrial Health, 23 : 155-160, 2007.
3. Ulker C.O., Ustundag A., Duydu Y., Yucesoy B., Karakaya A., Cytogenetic monitoring of coal workers and patients with coal workers’ pneumoconiosis in Türkiye. Environmental molecular and mutagenesis, 49: 232-237, 2008. 
4. Ulker C.O., Yucesoy B., Demir O., Tekin I.O. &  Karakaya A., Serum and BAL cytokine and antioxidant enzyme levels at different stages of pneumoconiosis in coal workers. Human and Experimental Toxicology, 27:871-877, 2008.
5. Akdemir C., Ulker O.C., Basaran A., Ozkaya S., Karakaya A., Estimation of ochratoxin A in some Turkish populations: an analysis in urine as a simple, sensitive and reliable biomarker. Food Chem Toxicol. 48(3):877-82, 2010. Epub 2010 Jan 6.
6. Ates I, Ulker OC, Akdemir C, Karakaya A. Correlation of Ochratoxin A exposure to urinary levels of 8-hydroxydeoxyguanosine and malondialdehyde in a Turkish population .  Bull Environ Contam Toxicol. 2011 Mar;86(3):258-62. Epub 2011 Feb 19.
7. Ulker OC, Atak A, Ates I, Karakaya A. Evaluation of auricular lymph node cell lymphocyte proliferation and cytokine production as non-radioactive endpoints during murine contact allergy.J Immunotoxicol. 2011 Jun;8(2):131-9. Epub 2011 Jan 31.
8. Ulker OC, Ates I, Atak A,  Karakaya A.,  Evaluation of Non-Radioactive Endpoints of Ex Vivo Local Lymph Node Assay-BrdU to Investigate Select Contact Sensitizers.J Immunotoxicol. 201310:1-8. 


PARTICIPATING CONGRESS

1. 8th International Symposium on Pharmaceutical Sciences (ISOPS-8), June 13-16, 2006, Ankara, Turkey. “Ulker C.O., Yucesoy B., Tekin O.I., Karakaya A., Neopterin as a marker for immune system activation in coal miners pneumoconiosis”
2. 43rd Congress of the European Societies of Toxicology (EUROTOX), 6th Congress of Toxicology in Developing Countries, September 20-24, 2006, Dubrovnik/Cavtat, Croatia. “ Ulker O.C., Ustundag A., Duydu Y., Yucesoy B.,  Karakaya A., Possible genotoxic risk in coal workers’ pneumoconiosis” (Oral Presentation)
3. 6th International Congress of Turkish Society of Toxicology, November 2-5, 2006, Antalya, Turkey. “Ulker O. C., Yucesoy B., Demir O., Karakaya A, Serum and BALF cytokine levels at different stages of pneumoconiosis in coal workers” 
4. 6th International Congress of Turkish Society of Toxicology, November 2-5, 2006, Antalya, Turkey. “ Karakaya A., Ulker O.C., Yucesoy B., Durucu M., Neopterin: A novel marker for immune activation in patients with CWP”
5. 5th International Congress on Environmental Mutagens in Human Populations, May 20-24, 2007, Antalya, Turkey. “Ulker O.C., Ustundag A., Duydu Y., Yucesoy B.,  Karakaya A., SCE and MN frequencies in coal workers and coal workers’pneumoconiosis patients”
6. The 3th  Euro-Asian Conference on Hazardous Waste & Human Health, March 27-30, 2008, Istanbul, Turkey. “Ulker O.C., Yucesoy B., Demir O., Tekin I.O., Karakaya A., Serum and BAL antioxidant enzyme levels as markers of effect in CWP patients”
7. 47th Annual Meeting of the Society of Toxicology, March 16-20, 2008, Seattle, USA. “Karakaya A., Akdemir C., Basaran A., Ulker O.C., Ozkaya S., Estimation of ochratoxin A in Turkish population: An analysis in urine as a simple, sensitive and reliable biomarker”
8. The 3th  Euro-Asian Conference on Hazardous Waste & Human Health, March 27-30, 2008, Istanbul, Turkey. “Karakaya A.,  Ulker O.C., Yucesoy B., Demir O., Tekin I.O., Serum and BAL cytokine levels as markers at different stages in CWP patients”
9. The 45th Congress of the European Societies of Toxicology, October 5-8 , 2008, Rhodes, Greece. “Ulker O.C., Yucesoy B., Demir O., Tekin I.O., Karakaya A. ,  Evaluation of antioxidant enzyme levels as biological markers at different stages of pneumoconiosis in coal workers”
10. The 45th Congress of the European Societies of Toxicology, October 5-8 , 2008, Rhodes, Greece, “Karakaya A.,  Ulker O.C., Yucesoy B., Demir O., Tekin I.O.,  Relationship of inflammatory cytokines with disease severity in CWP patients”
11. The 48th Annual Meeting of the Society of Toxicology,  March 15-19, 2009, Baltimore, USA,  “Karakaya A., Ulker O.C., Ates I., The murine local lymph node assay with non-radioactive alternative endpoints” 
12. 7th Congress of the Turkish Society of Toxicology with International Participation, 30 May-1 June 2009, Ankara, Turkey. “Ulker O.C., Karakaya A., Ates I., Investigation of allergy and irritancy potency of DNCB and paraphenylenediamine bu using nonradioactive LLNA” (Oral presentation)
13. 7th Congress of the Turkish Society of Toxicology with International Participation, 30 May-1 June 2009, Ankara, Turkey “Akdemir C., Ulker O.C., Basaran A., Ozkaya S., Karakaya A., Estimating ochratoxin A levels in urinary in Turkish population as a sensitive biomarker”  
14. The 9th International Symposium on Pharmaceutical Sciences (ISOPS-9), June 23-26 2009, Ankara, Turkey. “Ulker O.C., Ates I., Karakaya A., The murine local lymph node assay with nonradioactive alternative endpoints”
15. The 46th Congress of the European Societies of Toxicology, September 13-16 2009, Dresden, Germany, “Ulker O.C., Karakaya A., Evaluation of alternative endpoints for non-radioactive local lymph node assay by using two strong sensitizers”
16. 7th Congress of Toxicology in Developing Countries (CTDC), September 6-10 2009,  Sun City, South Africa, “Karakaya A., Akdemir C., Ulker O.C., Baþaran A., Ozkaya S., Estimation of ochratoxin A in some Turkish population: An analysis in urine as a simple, sensitive and reliable biomarker”
17. The 47th Congress of the European Societies of Toxicology, XII International Congress of Toxicology, July 19-23 2009, Barcelona, Spain “Karakaya A., Ulker O.C., Evaluation of cytokine production in auricular lymph nodes as an alternative endpoint during murine contact allergy” 
18. The 50th Annual Meeting of the Society of Toxicology, March 6-10 2011 Washington DC, USA “Karakaya A,  Ulker O.C.,  Ateþ I.,  Atak A.,Evaluation of the non-radioactive endpoints of  LLNA by applying moderate and weak sensitizers,” 
 19. The 48th Congress of European Societies of Toxicology, June 17-20 2012 Stockholm, Sweden “Ulker O.C., Ates I., Atak A., Karakaya A., Investigation of sensitizing potency of some cosmetic mixtures” 
  20. The 10th International Symposium on Pharmaceutical Sciences (ISOPS-10), June 26-29, 2012, Ankara, Turkey. “Ulker O.C., Ates I., Atak A., Karakaya A., “Investigation of the utility of the non-radioactive endpoints of ex vivo LLNA-BrdU method by using some cosmetic mixtures”
21. The 8th Congresses on Toxicology in Developing Countries (8th CTDC), September 10-13, 2012 Bankgog, Tailand, Karakaya A., Ulker O.C, Ates I, Atak A ., “Evaluation of contact sensitizing potential of fragrance mix and balsam of peru by using the ex vivo LLNA-BrdU method”  
 22. 8th Congress of the Turkish Society of Toxicology with International Participation, November 15-18, 2012, Antalya, Turkey. “ Ulker O., Kaymak Y., Karakaya A., Investigation of contact sensitization potency of fragrance mix and fragrance mix ingredients by using ex vivo nonradioactive local lymph node assay” (Oral presentation)
23. 8th Congress of the Turkish Society of Toxicology with International Participation, November 15-18, 2012, Antalya, Turkey. “ Karakaya A., Ulker O., Ates I., Atak A., Investigation of the dermal sensitization potential of cosmetic materials by using the ex vivo local lymph node assay-BrdU”

PARTICIPATING COURSES AND WORKSHOPS

Workshop on Alternative Methods Reduction, Refinement, Replacement to   Animal Tests, November 12-13, Ankara, Turkey

CASCADE course in “Regulatory Toxicology” , August 25-29, 2008, Kuopio, Finland (course fellowship)

Safe Handling of cytotoxic/hazardous drugs and Laminar flow and biosafety cabinet technology course, September 29, 2011, Ankara, Turkey.

Developments in Risk Assessment: Basic Concepts and International Frameworks for Evaluating Toxicity Data for Human Health Risk Assessment, November 14, 2012, Antalya, Turkey.

Chemicals regulation in EU. REACH and CLP- Legislation and Consequences, November 15, 2012, Antalya, Turkey. 




MEMBERSHIPS OF SCIENTIFIC AND PROFESSIONAL COMMUNITIES: IUTOX (International Union of Toxicology), EUROTOX (Federation of European Toxicologists and European Societies of Toxicology), Turkish Society of Toxicology

ADRESS:  Ankara University, Faculty of Pharmacy, Depertment of Toxicology, 06510, Ankara, Turkey
Tel: + 90 (312) 2033122 
e-mail: oulker@pharmacy.ankara.edu.tr