PROF.DR. FATMA GÜLGÜN OZANSOY    
Name : FATMA GÜLGÜN
Surname : OZANSOY
E-Mail :
Phone Number : 203 31 36
Title : PROF.DR.
Unit : FACULTY OF PHARMACY
Department :
Personal Information

 

EDUCATION

Ph.D.:  Ankara Üniversity, Faculty of Pharmacy, Physiology, 1986

M.Sc.:  Ankara Üniversity, Faculty of Pharmacy, 1976

 

PROFESSIONAL EXPERIENCES

 Prof. Dr.: Ankara Üniversity, Faculty of Pharmacy  2004-

Assoc.Prof.:  Ankara Üniversity, Faculty of Pharmacy, 1994-2004

Lecturer: Ankara Üniversity, Faculty of Pharmacy, 1989-1994

Res. assistant:  Ankara Üniversity, Faculty of Pharmacy, 1980-1986

 

ADMINISTRATIVE EXPERIENCES

Member: Pharmacology consulting committe at Ministry of Health (2002-2013)

Member: Manager Board (1997-2002)          

 

RESEARCH INTEREST

  • Diabetic dyslipidemia and treatment strategies
  • Diabetic cardiovascular complications and treatment strategies
  • Oxidative stress and antioxidants
  • Experimental menopause and vascular complications, treatment strategies

 

PROJECTS

     

·         A study on a new adult type 2 diabetic rat model: Pharmacodynamic interaction between pioglitazone and insulin on thoracic aorta: TÜBİTAK (Scientific and Technological Research Council of Turkey-SBAG-AYD-460. researcher)

·         Antioxidants and aldose reductase blockade in prevention of late diabetic complications: study on new pyridoindole derivatives, TÜBİTAK (Scientific and Technological Research Council of Turkey) -SBAG-2397 and ANKARA Univ- Research Grant -2001-08-03-031 , researcher)   

·         Effects of statin treatment on diabetic ventricular myocyte dysfunction in mice (ANKARA Univ, Res. Grant - 2005.08.03.053 , project leader) 

·         The role of estrogen receptors on  diabetic ovariectomized rats  induced vascular dysfunction and the effects of estrogen treatments. (ANKARA Univ, Res. Grant - BAP 2007 08 03 004 HP, project leader) 

·         Effects of low-dose, long-term fluvastatin treatment on oxidative/nitrosative parameters in peripheric tissues of STZ-diabetic rats Ankara Univ, Res. Grant, BAP- 2008 0803061 , researcher )

·         STZ- diabetic rats as a glyco-oxidatif aging model: Effects of pyridoindol Sme1C2 on vascular reactivity, endothel dysfunction and tissue protein oxidation. Ankara Univ, Res. Grant (10 B 336002, researcher)


·         Effects of aliskiren on insulin resistance and cardiovascular dysfunction in a rat model of diabetes mellitus: The high-fed, STZ-treated rat. (Ankara Univ, Res.  Grant researcher  )

 

SCI-PUBLICATIONS

 

 

·         Ceylan-Isik AF, Ari N, Stefek M, Sotnikova R, Ozansoy G, Horakova L, Karasu Ç., Effects of a long-term treatment with an antioxidant pyridoindole on vascular responsiveness in diabetes-induced aging rats. Curr Aging Sci. 4(2):150-7, 2011. 

·         Cumaoğlu A, Ozansoy G, Irat AM, Arıcıoğlu A, Karasu C, Arı N., Effect of long term, non cholesterol lowering dose of fluvastatin treatment on oxidative stress in brain and peripheral tissues of streptozotocin-diabetic rats., Eur J Pharmacol. 654(1):80-5,  2011.

·         Ceylan-Isik AF, Erdogan-Tulmac OB, Ari N, Ozansoy G, Ren J., Effect of 17beta-oestradiol replacement on vascular responsiveness in ovariectomized diabetic rats. Clin Exp Pharmacol Physiol. 36(11):e65-71, 2009.

·         Sahilli M, Irat AM, Işik AC, Karasu C, Ozansoy G, Ari N.,A lack of synergistic interaction between insulin and pioglitazone on reactivity of rat aorta from chronically high dose insulin-treated diabetic rats. Gen Physiol Biophys. 26(1):48-55, 2007.

·         Ceylan A, Karasu C, Aktan F, Ozansoy G.Simvastatin treatment restores vasoconstriction and the inhibitory effect of LPC on endothelial relaxation via affecting oxidizing metabolism in diabetic rats. Diabetes Nutr Metab  17(4):203-10, 2004.

·         Ozansoy G, Güven C, Ceylan A, Can B, Aktan F, Oz E, Gönül B., Effects of simvastatin treatment on oxidant/antioxidant state and ultrastructure of streptozotocin-diabetic rat lung. Cell Biochem Funct.;23(6):421-6, 2005.

·         Ceylan A, Karasu C, Aktan F, Güven C, Can B, Ozansoy G. Effects of simvastatin treatment on oxidant/antioxidant state and ultrastructure of diabetic rat myocardium. Gen Physiol Biophys. 22(4):535-47, 2003.

·         Ozansoy G, Akin FB. Effects  of gemfibrozil treatment on vascular reactivity of streptozotocin-diabetic  rat aorta. J. Pharm Pharmacol.;56(2):241-6, 2004.

·         Irat AM, Aktan F, Ozansoy G.Effects of L-carnitine treatment on oxidant/antioxidant state and vascular reactivity of streptozotocin-diabetic rat aorta. J. Pharm. Pharmacol. 55(10):1389-95, 2003.

·         Ulusu NN, Sahilli M, Avci A, Canbolat O, Ozansoy G, Ari N, Bali M, Stefek M, Stolc S, Gajdosik A, Karasu C.Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E. Neurochem Res.;28(6):815-23, 2003.

·         Ozansoy G, Akin B, Aktan F, Karasu C.Short-term gemfibrozil treatment reverses lipid profile and peroxidation but does not alter blood glucose and tissue antioxidant enzymes in chronically diabetic rats. Mol Cell Biochem.;216(1-2):59-63, 2001.

·         Karasu C, Ozansoy G, Bozkurt O, Erdoğan D, Omeroğlu S. Changes in isoprenaline-induced endothelium –dependent and independent relaxations of aorta in long –term STZ-diabetic rats:reversal effect of dietary vitamin E. Gen Pharmacol.;29(4):561-7, 1997.

·         Karasu C, Ozansoy G, Bozkurt O, Erdoğan D, Omeroğlu S.Antioxidant and triglyceride-lowering effects of vitamin E associated with the prevention of abnormalities in the reactivity and morphology of aorta from streptozotocin-diabetic rats. Antioxidants in Diabetes-Induced Complications (ADIC) Study Group.Metabolism.;46(8):872-9, 1997 .

·         Ozansoy G, Karasu C, Altan VM.The effects of acetylcholine on insulin-dependent and non-insulin-dependent diabetic rat tracheal segments. Gen Pharmacol.;24(1):159-64,1993 .

·         Ozansoy G, Karasu C, Ozçelikay AT.The effect of oral vanadyl treatment on the reactivity of tracheal smooth muscle obtained from insulin-dependent diabetic rats.

      Gen Pharmacol.;24(1):115-9,1993.