ÖĞR. GÖR. DR. MAHMUT PARMAKSIZ    
Name : MAHMUT
Surname : PARMAKSIZ
E-Mail : parmaksiz@ankara.edu.tr, mahmut.parmaksiz@gmail.com
Phone Number : (312) 583 6700 / 6662
Title : ÖĞR. GÖR. DR.
Unit :
Department : Ankara University Stem Cell Institute
ABS Url:https://abs.ankara.edu.tr/mahmut-parmaksiz
Personal Information

 Mahmut PARMAKSIZ

CONTACT

Address         :          Ankara University Stem Cell Institute 

                                   Ceyhun Atuf Kansu Cad. No:169 Cevizlidere/ 06520

                                   Ankara, Turkey

Telephone   :         +90 (312) 583 67 00 (6662)

                                   

E-Mail             :          mahmut.parmaksiz@gmail.com

                                   parmaksiz@ankara.edu.tr


EDUCATION

B.S.                                     : Ankara University, Faculty of Science,

Department of Chemistry (2010)

M.Sc                                   : Ankara University, Faculty of Science,

Department of Chemistry/Biochemistry (2012)

PhD.                                   : Ankara University, Faculty of Science,

Department of Chemistry/Biochemistry (2018)

 

PROFESSIONAL EXPERIENCE

Ankara University Stem Cell Institute, 

Lecturer PhD. 2014 – 

 

ADMINISTRATIVE DUTIES

Support Agent Against Sexual Abuse and Sexual Assault (2017-)

GMP – Tissue and Cell Manufacturing Center Quality Control Manager (2014-2018) 


SCI-INDEXED JOURNAL ARTICLES

1)    Parmaksiz, M, Elçin, AE, Elçin, YM. 2020. Decellularized Cell Culture ECMs Act as Cell Differentiation Inducers. Stem Cell Rev and Rep. https://doi.org/10.1007/s12015-020-09963-y.

 

2)     Kilic P, Bay M, Yildirim Y, Coskun O, Seker S, Baydin P, Lalegul Ulker O, Parmaksiz M et al. 2019. A CD34+ Cell Enrichment Protocol of Hematopoietic Stem Cells in a Well-Established Quality Management System. Cells Tissues Organs. 207(1):15-20.

 

3)     Parmaksiz M, Elçin AE, Elçin YM. 2019. Decellularized bovine small intestinal submucosa-PCL/hydroxyapatite-based multilayer composite scaffold for hard tissue repair.  Materials Science and Engineering: C, 94: 788-797.

 

4)     Sezgin-Bayindir Z, Elcin AE, Parmaksiz M, Elcin YM, Yuksel N. 2018. Investigations on clonazepam-loaded polymeric micelle-like nanoparticles for safe drug administration during pregnancy. J Microencapsul. 35(2):149-164.

 

5)     Parmaksiz M., Elcin AE., Elcin YM., 2017. "Decellularization of bovine small intestinal submucosa and its use for the healing of a critical-sized full-thickness skin defect, alone and in combination with stem cells, in a small rodent model", Journal of Tissue Engineering and Regenerative Medicine, 11(6), 1754-176.

 

6)     Elcin AE, Parmaksiz M, Dogan A, Seker S, Durkut S, Dalva K, Elçin YM. 2017. Differential gene expression profiling of human adipose stem cells differentiating into smooth muscle-like cells by TGFβ1/BMP4. Experimental cell research 352 (2), 207-217.

 

7)     Parmaksiz M., Dogan A, Odabas S., Elçin AE., Elçin YM,. 2016, "Clinical applications of decellularized extracellular matrices for tissue engineering and regenerative medicine", Biomedical Materials, 11(2), 22003.

 

8)     Sezgin-Bayindir Z, Ergin AD, Parmaksiz M, Elcin AE, Elcin YM, Yuksel N. 2016. Evaluation of various block copolymers for micelle formation and brain drug delivery: In vitro characterization and cellular uptake studies. Journal of Drug Delivery Science and Technology, 36, 120-129.

 

9)     Aktas SH, Akbulut H, Elcin AE, Parmaksiz M, Keskin AA, Coleri Cihan A, Elcin YM, İcli F. 2016. Baculoviral vector loaded mesenchymal stem cells as efficient gene therapy tools for cancer treatment. Turkish Journal Of Biology, 40, 1121-1128.

 

10)   Ergin E, Dogan A, Parmaksiz M, Elçin AE, Elçin YM. 2016.  Time-Resolved Fluorescence Resonance Energy Transfer [TR-FRET] Assays for Biochemical Processes. Curr Pharm Biotechnol. 17(14):1222-1230.

 

11)   Dogan A, Parmaksız M, Elçin AE, Elçin YM. 2016. Extracellular Matrix and Regenerative Therapies from the Cardiac Perspective. Stem Cell Rev. 12(2):202-13.

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BOOK CHAPTERS / PROTOCOLS

1) Oztürk S, Ayanoglu FB, Parmaksiz M, Elçin AE, Elçin YM. 2020. Clinical impacts of biocompatibility: What surgeons ought to know. Handbook of Biomaterials Biocompatibility 1st Edition, Woodhead Publishing 2020. doi: 10.1016/B978-0-08-102967-1.00012-8

2)  Parmaksiz M, Elçin AE, Elçin YM. 2018. Decellularized bSIS-ECM as a Regenerative Biomaterial for Skin Wound Repair. Methods Mol Biol. Humana Press, New York, NY June 28. doi: 10.1007/7651_2018_147.

3)  Parmaksiz M, Elçin AE, Elçin YM. 2017. Decellularization of Bovine Small Intestinal Submucosa. Methods Mol Biol. Humana Press, New York, NY Apr 28. doi: 10.1007/7651_2017_33.

 

PROJECTS

1)   "Development and Characterization of Biomimetic Composite Grafts for Hard Tissue Repair". Ankara University Research Fund (AU-BAP), Project No. 19H0216001 (2019-) (Coordinator)

 

2)   “Development of a Living Perio/Osteo Microfluidic Tissue-on-a-Chip System Using 3D-Bioprinting, and Evaluation of Model Drug Interactions”. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No. 117M281 (COST-CA16119).Researcher


3)    “Comparative Efficacy Evaluation of Pluripotent, Multipotent and Somatic Cell Culture-Derived Extracellular Matrix as Natural Niche and as Biomimetic Component in Tissue Engineering Scaffold”. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No. 214M159 (COST Project BM1302) (Scholar/Researcher)


4)   “Clinical Studies on The Use of Mesenchymal Stem Cells in Canine Spinal Cord Trauma”. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No. 111O428. (Scholar/Researcher) 


5)     “Mechanoactive Vascular Graft Engineering with Adipose Mesenchymal Stem Cells”. The Scientific and Technological Research Council of Turkey (TÜBİTAK), Project No. 111M336 (COST Project MP1206).(Scholar/Researcher)


6)   “Molecular Evaluation of Human Adipose Derived Mesenchymal Stem Cells Differentiating Into Vascular Smooth Muscle Cells”. Ankara University Research Fund (AU-BAP), Project No. 14B0216001. (Researcher)


7)   “Isolation and In Vitro Characterization of Human cardiac Progenitor Cells”. Ankara University Research Fund (AU-BAP).(Researcher) 

 

 

PATENTS

1)    Mahmut Parmaksız, Yaşar Murat Elçin, Ayşe Eser Elçin “Bovine Derived Regenerative Biomaterial”, TPE Patent No: 2013/14952. (Biovalda Sağlık Teknolojileri A.Ş.) 2017.

 

FELLOWSHIPS / AWARDS

1)  TUBİTAK BİDEB 2219-International Postdoctoral Research Fellowship (2019)

2)  Best Poster Award, “Decellularized Bovine Small Intestinal Submucosa as a Regenerative Matrix Application in Wound Healing with BM MSCs. (BIOMED 2011)

 

CONFERENCE PROCEEDINGS

1)    Parmaksiz, M., Arslan YE, Elcin, A.E., Elcin, Y.M. 2011. Decellularized Bovine SIS Hydroxyapatite Composite Multilayers for Hard Tissue Repair. 17th International Symposium on Biomedical Science and Technology" (BIOMED 2011).

 

2)    Parmaksiz, M., Arslan YE, Elcin, A.E., Elcin, Y.M. 2011. Decellularized Bovine Small Intestinal Submucosa as a Regenerative Matrix  Application in Wound Healing with BM MSCs.  17th International Symposium on Biomedical Science and Technology" (BIOMED 2011). 

 

3)    Parmaksiz, M., Arslan YE, Elcin, A.E., Elcin, Y.M. 2012. Preparation of bovine small intestinal submucosa and application as a wound dressing alone or seeded with mesenchymal stem cells in a full thickness rat skin defect.  TERMIS-EU-2012. European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2012. 

 

4)    Sezgin-Bayindir Z, Ergin AD, Parmaksiz M, Elcin AE, Elcin YM, Yuksel N. 2015. Cytotoxicity of various micelle forming copolymers on brain cell line. Annual Meeting-System Approaches for Better Medicines and Health. 

 

5)    Akbulut H., Aktas S.H., Elcin A.E., Parmaksiz M., Keskin A.A, Cihan A.C, Elcin Y.M., and Icli M. 2016. “Mesenchymal stem cell directed baculoviral gene therapy of colon cancer.“ 2016 ASCO (American Society of Clinical Oncology) Annual Meeting, McCormick Place, Chicago, Illinois, USA, (J. Clin. Oncol., 34, 2016, suppl; abstr e14573), 3-7th June 2016. 

 

6)    Yuksel N, Sezgin-Bayindir Z, Ergin AD, Parmaksiz M, Elcin AE, Elcin YM. 2017. Evaluation Of Polymeric Micelles Prepared From Various Block Copolymers for Brain Targeting: In Vitro Cellular Uptake Studies. 21st International Symposium on Microencapsulation - Faro, Portugal - September 27-29, 2017. 

 

7)    Parmaksiz, M., Elcin, A.E., Elcin, Y.M. (2017). Development of decellularized somatic and multipotent cell culture-derived extracellular matrices for regenerative applications.  TERMIS-EU 2017 (European Chapter Meeting of the Tissue Engineering and Regenerative Medicine International Society 2017)

 

8)    Elcin, A.E., Seker S, Baydin P, Dalva K, Parmaksiz M, Lalegul O, Cubukcuoglu Deniz G, Erden A, Gurman G, Arslan O, Elcin YM. 2017. Isolation and Culture of Good Manufacturing Practice Grade Human Bone Marrow-Derived Mesenchymal Stem Cells for Clinical Applications.  BIOMED 2017 (22nd International Symposium on Biomedical Science and Technology)

 

9)    Parmaksiz, M., Elcin, A.E., Elcin, Y.M. 2017. Evaluating the efficiency of decellularization protocols for cell culture derived ECM.  BIOMED 2017 (22nd International Symposium on Biomedical Science and Technology)


10) Elcin, Y.M., Parmaksiz, M., Vurat, M.T., Lalegul-Ulker, O., Durkut, S., Koc-Demir, A., Elcin, A.E.. 2019. Magneto-Sensitive Decellularized Bone Matrix as a Regenerative Biomaterial. AAAFM 2019 (Advances in Functional Materials Conference) UCLA, USA.

 

11) Elcin, A.E., Parmaksiz, M., Vurat, M.T., Elcin, Y.M. Optimization of the Decellularization Process of Adipose Stem Cell Cultures. 3rd CellFit Annual Meeting, 2019. 

 

12) Parmaksiz, M., Vurat M.T., Seker, S., Elcin, A.E., Lalegul-Ulker, O., Elcin, Y.M. Development of an In-Vitro Perio/Osteo Micro-Tissue Using 3D-Bioprinting. 3rd CellFit Annual Meeting, 2019.