DOÇ.DR. PINAR HURİ    
Adı : PINAR
Soyadı : HURİ
E-posta : phuri@ankara.edu.tr
Tel : +90.312.600 01 00 / 1849
Ünvan : DOÇ.DR.
Birim : MÜHENDİSLİK FAKÜLTESİ
Bölüm : Biyomedikal Mühendisliği
Kişisel Akademik Bilgiler

Doç. Dr. Pınar Yılgör Huri

web: http://mtelab.ankara.edu.tr/

Araştırma Konuları:   

Biyomalzemeler; Doku Mühendisliği; Kemik, Kas, Tendon, Ligament Greftleri; Erişkin Kök Hücreler; Kontrollü Salım Sistemleri; Biyobozunur Polimerler; 3D Biyoyazıcı Sistemleri; Anatomik ve Cerrahi Modeller 

Eğitim:

Post-doktora: Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Translational Tissue Engineering Center, Laboratory for Craniofacial and Orthopedic Tissue Engineering, Baltimore, MD, USA 2012-2014

Bütünleşik Doktora: Orta Doğu Teknik Üniversitesi Fen Bilimleri Enstitüsü, Biyoteknoloji EABD, Ankara, Türkiye ve Minho Üniversitesi Polimer Mühendisliği Bölümü, Braga, Portekiz (EXPERTISSUES Integrated European PhD Program) 2004-2009

Yüksek Lisans: Orta Doğu Teknik Üniversitesi Fen Bilimleri Enstitüsü, Kimya Mühendisliği ABD, Ankara, Türkiye 2002-2004

Lisans: Gazi Üniversitesi Mühendislik-Mimarlık Fakültesi, Kimya Mühendisliği Bölümü, Ankara, Türkiye 1998-2002

Patentler:

1.   "Bone Regeneration Using Stromal Vascular Fraction, Platelet Derived Growth Factor-Rich Hydrogel, Three-Dimensional Printed Poly-E-Caprolactone Scaffolds"

       Grayson WL, Cook CA, Hung BPJ, Huri P, Hutton DL, Temple J. 

       United States Patent

       USPTO Patent No: US 20160095958 A1, 2016. 

2.   "Bone Plate"

       Lazoglu I, Huri G, Huri P.

       European Patent  

       EPO Patent No: EP2890313 (B1), 2015.

3.   "Bone Plate"

       Lazoglu I, Huri G, Huri P.

       Japanese Patent

       JPO Patent No: JP5895104 B2, 2015.

4.   "Bone Plate"

       Lazoglu I, Huri G, Huri P.

       United States Patent

       USPTO Patent No: US9138270 B2, 2015.

5.   "Kemik plağı"

       Huri G, Lazoglu I, Huri P, Mamedov A.

       Türk Patenti  

       TPE  Patent No: 2012-09867, 2015. 

 

Ödüller:

1.      “Yapay Kan” başlıklı çalışma ile ARGETİ Uluslararası Yatırım Fikirleri Proje Pazarı 1.lik Ödülü, Gaziantep Üniversitesi, 2017.

2.      TÜBA Üstün Başarılı Genç Bilim İnsanları Ödülü- GEBİP 2016

3.      Gold Medal for the “Adjustable Bone Plate Patent” from the World Intellectual Property Organization, 2016.

4.      Best Academic Patent Award for the “Adjustable Bone Plate Patent” from the International Federation of Inventor Association (IFIA), 2016.

5.      Poster Ödülü, 27. Ulusal Biyokimya Kongresi, "Hemoglobinin tartarik asit kaplı magnetite immobilizasyonu, karakterizasyonu ve redoks özellikleri", 2015.

6.      Bilim Akademisi Genç Bilim İnsanları Ödülü- BAGEP 2015

7.      Journal of Biomaterials and Tissue Engineering Best Paper Award with paper titled "Proliferation and Differentiation of Mesenchymal Stem Cells in Chitosan Scaffolds Loaded with Nanocapsules Containing Bone Morphogenetic Protein-4, Platelet-Derived Growth Factor and Insulin-Like Growth Factor 1", American Scientific Publishers, 2014.

8.      Young Investigator Travel Award, ASBMR 2013- The American Society for Bone and Mineral Research 2013 Annual Meeting, Baltimore, USA, 2013.

9.      New Investigator Recognition Award, Orthopedic Research Society 2013 Annual Meeting, San Antonio, Texas, USA, 2013.

10.    Best Poster Award from 42nd National Periodontology Congress with the poster titled “Çeşitli büyüme faktörleri içeren nano kapsüllerle hazırlanmış üç boyutlu kitosan iskele yapılarının insan mezenşimal kök hücrelerinin proliferasyonu ve osteojenik farklılaşması üzerine etkisinin değerlendirilmesi”, 2012.

11.    Best Poster Award from 17th International Biomedical Science and Technology Symposium with the poster titled “Effect of Pore Volume and Architecture of 3D Scaffolds on the Mechanical Properties of Regenerating Bone”, 2011.

12.    European Biomaterials and Tissue Engineering Doctoral Award by European Society for Biomaterials (ESB), 2011

13.    METU Graduate School of Natural and Applied Sciences Thesis of the Year Award with PhD Thesis: Sequential Growth Factor Delivery from Polymeric Scaffolds for Bone Tissue Engineering, 2009.

 

Yayınlar: Citations: 707; h index: 13 (Scopus, Sept 2017)

Araştırma Makaleleri 

1.        Cook CA, Yilgor Huri P, Ginn BP, Temple JP, Gilbert JE, Mao HQ, Grayson WL.  Characterization of a Novel Bioreactor System for 3D Cellular Mechanobiology Studies. Biotechnol Bioeng 2016; 113: 1825-1837. 

2.        Yilgor Huri P. Kemik Doku Mühendisliği ve KDM için Kontrollü Salım Sistemleri, Turkiye Klinikleri J Med Oncol-Special Topics 2015; 8(2): 98-103.

3.        Yilgor Huri P. Effect of Culture Conditions on the Multinucleation of Human Adipose-Derived Stem Cells. J Biomater Tissue Eng, 2015; 5 (3): 234-240. 

4.        Yilgor Huri P, Wang A, Spector AA, Grayson WL. Multistage Adipose-Derived Stem Cell Myogenesis: An Experimental and Modeling Study. Cell Mol Bioeng, 2014; 7(4): 497-509

5.        Aydemir Sezer U, Billur D, Huri G, Yilgor Huri P, Aksoy EA, Terzioglu H, Hasirci V, Hasirci N. In vivo performance of poly(ε-caprolactone) constructs loaded with gentamicin releasing composite microspheres for use in bone regeneration. J Biomater Tissue Eng, 2014; 4: 786-795.   

6.        Yilgor Huri P, Ozilgen AB, Hutton DL, Grayson WL. Scaffold Pore Size Modulates In Vitro Osteogenesis of Human Adipose-Derived Stem/Stromal Cells. Biomed Mater, 2014; 9(4): 045003. doi: 10.1088/1748-6014/9/4/045

7.        Temple JP, Hutton DL, Hung BP, Yilgor Huri P, Cook CA, Kondragunta R, Jia X, Grayson WL. Engineering Anatomically-Shaped Vascularized Bone Grafts with hASCs and 3D-Printed PCL Scaffolds. J Biomed Mater Res A, 2014; 102A: 4317-4325

8.        Saygun I, Bal V, Kiziltay A, Yilgor Huri P, Avcu F, Üstün K, Hasirci V, Hasirci N. Proliferation and Differentiation of Mesenchymal Stem Cells in Chitosan Scaffolds Loaded with Nanocapsules Containing Bone Morphogenetic Protein-4, Platelet-Derived Growth Factor and Insulin-Like Growth Factor 1. J Biomater Tissue Eng, 2014; 4: 181-188

9.        Yilgor Huri P, Cook CA, Hutton DL, Goh BC, Gimble JM, DiGirolamo DJ, Grayson WL. Biophysical Cues Enhance Myogenesis of Adipose Derived Stem Cells. Biochem Bioph Res Co, 2013; 438(1): 180-185

10.    Ucar S, Yilgor P, Hasirci V, Hasirci N. Chitosan Based Wet Spun Scaffolds for Bioactive Agent Delivery in Bone Tissue Engineering. J Appl Polym Sci, 2013; 130: 3759–3769.

11.    Yilgor Huri P, Huri G, Yasar U, Ucar Y, Dikmen N, Hasirci N, Hasirci V. A Biomimetic Growth Factor Delivery Strategy for Enhanced Regeneration of Iliac Crest Defects. Biomed Mater, 2013; 8: 045009. doi:10.1088/1748-6041/8/4/045009

12.    Ertan AB, Yilgor P, Bayyurt B, Calikoglu AC, Kaspar C, Kok FN, Kose GT, Hasirci V. Effect of Double Growth Factor Release on Cartilage Tissue Engineering. J Tissue Eng Regen Med, 2013;7:149-160.

13.    Yilgor P, Yilmaz G, Onal MB, Solmaz I, Gundogdu S, Keskil S, Sousa RA, Reis RL, Hasirci N, Hasirci V. An In Vivo Study on Effect of Scaffold Geometry and Growth Factor Release on the Healing of Bone Defects. J Tissue Eng Regen Med, 2013;7:687-696.

14.    Yilgor C, Yilgor Huri P, Huri G. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells Int 2012, Article ID 374676, doi:10.1155/2012/374676.  

15.    Yasar U, Yilgor Huri P, Dikmen N. Artificial Blood. Archives Medical Review Journal 2012;21(2):95-108.

16.   Demirbag B*, Yilgor Huri P*, Kose GT, Buyuksungur A, Hasirci V. Advanced Cell Therapies with and without Scaffolds. Biotech J 2011;6(12):1437-1453.

17.    Yilgor P, Sousa RA, Reis RL, Hasirci N, Hasirci V. Effect of Scaffold Architecture and BMP-2/BMP-7 Delivery on in vitro Bone Regeneration. J Mater Sci Mater Med 2010;21:2999-3008

18.    Yilgor P, Hasirci N, Hasirci V. Sequential BMP-2/BMP-7 Delivery from Polyester Nanocapsules. J Biomed Mater Res 2010;93A:528-536.

19.    Yilgor Huri P, Hasırcı N, Hasırcı V. Bone Tissue Engineering. Archives Medical Review Journal 2010;19(4):206-219.

20.    Yilgor P, Tuzlakoglu K, Reis RL, Hasirci N, Hasirci V. Incorporation of a Sequential BMP-2/BMP-7 Delivery System into Chitosan-Based Scaffolds for Bone Tissue Engineering. Biomaterials 2009;30:3551–3559.

21.   Zorlutuna P, Yilgor P, Basmanav FB, Hasirci V. Biomaterials and Tissue Engineering Research in Turkey: The METU BIOMAT Center Experience. Biotech J 2009;4:965-980.

22.    Yilgor P, Sousa RA, Reis RL, Hasirci N, Hasirci V. 3D Plotted PCL Scaffolds for Stem Cell Based Bone Tissue Engineering. Macromol Symp 2008;269:92-99.

23.    Hasirci V, Vrana E, Zorlutuna P, Ndreu A, Yilgor P, Basmanav B, Aydin E. Nano biomaterials; A review of the existing science and technology, and new approaches. J Biomater Sci Polymer Ed 2006;17(11):1241-1268. 

24.    Calik P, Yilgor P, Demir AS. Influence of controlled-pH and uncontrolled-pH operations on recombinant benzaldehyde lyase production by Escherichia coli. Enzym Microb Tech 2006;38(5):617-627

25.    Calik P, Yilgor P, Ayhan P, Demir AS. Oxygen Transfer Effects On Recombinant Benzaldehyde Lyase Production. Chem Eng Sci 2004;59:5075-5083.  


Kitap Bölümleri

1.           Hasirci V, Yilgor Huri P, Endogan T, Eke G, Hasirci N. Polymer Fundamentals: Polymer Synthesis. In: P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick (eds.) Comprehensive Biomaterials, vol. 2, Elsevier, 2016, Basımda. 

2.           Yilgor Huri P, Gilbert J, Morrissette-McAlmon J, Somers S, Grayson WL. Myogenic Differentiation of ASCs using Biochemical and Biophysical Induction. In: B. A. Bunnell, J. M. Gimble (eds.) Adipose Derived Stem Cells: Methods and Protocols, Second Edition. Basımda, Springer, 2016.

3.           Hung BP, Yilgor Huri P, Temple JP, Dorafshar A, Grayson WL. Craniofacial Bone. In: L. G. Zhang, J. P. Fisher (eds.) 3D Bioprinting and Nanotechnology in Tissue Engineering. Chapter 10, pg 213-228, Elsevier Publishing, 2015.(ISBN: 978-0-12-800547-7)

4.           Yilgor Huri P, Temple JP, Hung BP, Cook CA, Grayson WL. Bioreactor Technology for Engineering Craniofacial Tissues. In: A. Vishwakarma, P. Sharpe, S. Shi, X. Wang, M. Ramalingam (eds.) Stem Cell Biology and Tissue Engineering in Dental Sciences. Part II, Chapter 9, pg 117-132, Elsevier Publishing, 2015. (ISBN: 978-0-12-397157-9) 

5.           Karakecili A, Tigli Aydin S, Yilgor Huri P. Doku Mühendisliği. In: M. H. Asyalı, S. Kara, B. Yilmaz (Eds.) Biyomedikal Mühendisliğinin Temelleri. Chapter 13, pg 433-475, Nobel Yayınevi, 2014. (ISBN: 978-605-133-943-6)

6.           Yilgor Huri P, Grayson WL. Engineering Functional Bone Grafts for Craniofacial Regeneration. In: L.G. Zhang, A. Khademhosseini, T. Webster (eds.) Tissue and Organ Regeneration: Advances in Micro and Nanotechnology, Chapter 17, pg 589-620, Pan Stanford Publishing, 2014. (ISBN: 978-981-4411-67-7).

7.           Hasirci V, Yilgor P, Endogan T, Eke G, Hasirci N. Polymer Fundamentals: Polymer Synthesis. In: P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick (eds.) Comprehensive Biomaterials, vol. 1, 349-371, Elsevier, 2011. (ISBN: 978-0-08-055294-1)

8.           Yilgor P, Yucel D, Kenar H, Hasirci V. Polyhydroxyalkanoates: a Versatile Class of Biopolymers, and Their Biomedical Potential. Brazilian Network Of Green Chemistry: Awareness, Responsibility And Action. Ed. Carioca JOB, Chapter 20, 415-431, 2008. (ISBN: 978-85-7282-289-3)

 

 

Tez Danışmanlığı:

1.  Emre Ergene, Ankara Üniversitesi Biyoteknoloji Enstitüsü, Doktora 2017+

2.  Emre Ergene, Ankara Üniversitesi Biyoteknoloji Enstitüsü, Yüksek Lisans 2015-2017.

3. Şeniz Uçar (Eş Danışman, Danışman: Prof. N. Hasırcı), ODTÜ Fen Bilimleri Enstitüsü, Kimya Bölümü Yüksek Lisans 2010-2012.

 

İdari Görevler:

1.  Bölüm Başkan Yardımcısı, Ankara Üni. Biyomedikal Müh. Bölümü 2015+

2.  Fakülte Yönetim Kurulu Üyesi, Ankara Üni. Mühendislik Fakültesi 2015-2016.

 

 Üyelikler:

1.   European Society for Biomaterials (ESB) 2013+

2.   Orthopedic Research Society 2012+

3.   BIOMATEN Center of Excellence in Biomaterials and Tissue Engineering 2011+

4.   Biomaterials and Tissue Engineering Society (Turkey) 2009+

5.   Tissue Engineering and Regenerative Medicine International Society 2008+