ASSOC.PROF.DR. PINAR HURİ    
Name : PINAR
Surname : HURİ
E-Mail : phuri@ankara.edu.tr
Phone Number : +90.312.600 01 00 / 1849
Title : ASSOC.PROF.DR.
Unit : FACULTY OF ENGINEERING
Department : Biomedical Engineering
Personal Information

Assoc. Prof. Dr. Pınar Yılgör Huri

http://mtelab.ankara.edu.tr/

http://meditam.ankara.edu.tr/

 

Research Field:   

3D Bioprinting; 3D Printers; Biomaterials; Tissue Engineering; Bioreactors; Adult Stem Cells; Controlled Release Systems; Biodegradable Polymers   


Education:

Postdoc: Johns Hopkins University School of Medicine, Department of Biomedical Engineering, Translational Tissue Engineering Center, Baltimore, MD, USA, 2014

Integrated PhD: METU Department of Biotechnology Ankara, Turkey, and University of Minho Department of Polymer Engineering, Braga, Portugal (EXPERTISSUES Integrated European PhD Program), 2009

MSc: METU Department of Chemical Engineering, Ankara, Turkey, 2004

BSc: Gazi University Department of Chemical Engineering, Ankara, Turkey, 2002


Patents:

1. "Bone Regeneration Using Stromal Vascular Fraction, Platelet Derived Growth Factor-Rich Hydrogel, Three-Dimensional Printed Poly-E-Caprolactone Scaffolds". Grayson WL, Cook CA, Hung BPJ, Huri P, Hutton DL, Temple J. United States Patent USPTO Patent No: US 20160095958 A1, 2016.

2. "Bone Plate". Lazoglu I, Huri G, Huri P. European Patent EPO Patent No: EP2890313 (B1), 2015.

3. "Bone Plate". Lazoglu I, Huri G, Huri P. Japanese Patent JPO Patent No: JP5895104 B2, 2015.

4. "Bone Plate". Lazoglu I, Huri G, Huri P. United States Patent USPTO Patent No: US9138270 B2, 2015.

5. "Kemik plağı". Huri G, Lazoglu I, Huri P, Mamedov A. Turkish Patent TPE  Patent No: 2012-09867, 2015.

 

Awards:

1. Health Institutes of Turkey TÜSEB Aziz Sancar Science and Incentive Award, 2017

2. Project Award from Gaziantep University with project titled “Artificial Blood”, 2017

3. Turkish Academy of Sciences, Outstanding Young Scientist Award,  GEBİP 2016

4. Gold Medal with patent “Bone Plate”, World Intellectual Property Organization, 2016

5. Best Academic Patent Award, with patent “Bone Plate”, International Federation of Inventor Association (IFIA), 2016

6. Science Academy, Young Scientist Award BAGEP 2015

7. Poster Award, 27th National Biochemistry Congress, 2015

8. Journal of Biomaterials and Tissue Engineering Best Paper Award, 2014  

9. Young Investigator Travel Award, American Society for Bone and Mineral Research, 2013.

10. New Investigator Recognition Award, Orthopedic Research Society, 2013

11. Best Poster Award, 42nd National Periodontology Congress, 2012.

12. Best Poster Award, 17th International Biomedical Science and Technology Symposium, 2011.

13. European Biomaterials and Tissue Engineering Doctoral Award, European Society for Biomaterials (ESB), 2011.

14. METU Graduate School of Natural and Applied Sciences Thesis of the Year Award, 2009

 

PublicationsCitations: 745; h index: 13 (Scopus, Jan 2018)

Articles

1. Bayrak E, Yilgor Huri P. Engineering Musculoskeletal Tissue Interfaces. Front. Mater. doi: 10.3389/fmats.2018.0002.

2. Yilgor Huri P, Hamsici S, Ergene E, Huri G, Doral MN. Infrapatellar Fat Pad-Derived Stem Cell Based Regenerative Strategies in Orthopaedic Surgery. Knee Surg Rel Res, 2018; doi.org/10.5792/ksrr.17.061.

3. Cook CA, Yilgor Huri P, Ginn BP, Temple JP, Gilbert JE, Mao HQ, Grayson WL.  Characterization of a Novel Bioreactor System for 3D Cellular Mechanobiology Studies. Biotechnol Bioeng, 2016; 113: 1825–1837.

4. Yilgor Huri P. Kemik Doku Mühendisliği ve KDM için Kontrollü Salım Sistemleri, Turkiye Klinikleri J Med Oncol-Special Topics 2015; 8(2): 98-103.

5. Yilgor Huri P. Effect of Culture Conditions on the Multinucleation of Human Adipose-Derived Stem Cells. J Biomater Tissue Eng, 2015; 5 (3): 234-240.

6. Yilgor Huri P, Wang A, Spector AA, Grayson WL. Multistage Adipose-Derived Stem Cell Myogenesis: An Experimental and Modeling Study. Cell Mol Bioeng, 2014; 7(4): 497-509. 

7. Aydemir Sezer U, Billur D, Huri G, Yilgor Huri P, Aksoy EA, Terzioglu H, Hasirci V, Hasirci N. In vivo performance of poly(ε-caprolactone) constructs loaded with gentamicin releasing composite microspheres for use in bone regeneration. J Biomater Tissue Eng, 2014; 4: 786-795. 

8. Yilgor Huri P, Ozilgen AB, Hutton DL, Grayson WL. Scaffold Pore Size Modulates In Vitro Osteogenesis of Human Adipose-Derived Stem/Stromal Cells. Biomed Mater, 2014; 9(4): 045003. doi: 10.1088/1748-6014/9/4/045003

9. Temple JP, Hutton DL, Hung BP, Yilgor Huri P, Cook CA, Kondragunta R, Jia X, Grayson WL. Engineering Anatomically-Shaped Vascularized Bone Grafts with hASCs and 3D-Printed PCL Scaffolds. J Biomed Mater Res A, 2014; 102A: 4317-4325.

10. Saygun I, Bal V, Kiziltay A, Yilgor Huri P, Avcu F, Üstün K, Hasirci V, Hasirci N. Proliferation and Differentiation of Mesenchymal Stem Cells in Chitosan Scaffolds Loaded with Nanocapsules Containing Bone Morphogenetic Protein-4, Platelet-Derived Growth Factor and Insulin-Like Growth Factor 1. J Biomater Tissue Eng, 2014; 4: 181-188.

11. Yilgor Huri P, Cook CA, Hutton DL, Goh BC, Gimble JM, DiGirolamo DJ, Grayson WL. Biophysical Cues Enhance Myogenesis of Adipose Derived Stem Cells. Biochem Bioph Res Co, 2013; 438(1): 180-185.

12. Ucar S, Yilgor P, Hasirci V, Hasirci N. Chitosan Based Wet Spun Scaffolds for Bioactive Agent Delivery in Bone Tissue Engineering. J Appl Polym Sci, 2013; 130: 3759–3769.

13. Yilgor Huri P, Huri G, Yasar U, Ucar Y, Dikmen N, Hasirci N, Hasirci V. A Biomimetic Growth Factor Delivery Strategy for Enhanced Regeneration of Iliac Crest Defects. Biomed Mater, 2013; 8: 045009. doi:10.1088/1748-6041/8/4/045009

14. Ertan AB, Yilgor P, Bayyurt B, Calikoglu AC, Kaspar C, Kok FN, Kose GT, Hasirci V. Effect of Double Growth Factor Release on Cartilage Tissue Engineering. J Tissue Eng Regen Med, 2013;7:149-160.

15. Yilgor P, Yilmaz G, Onal MB, Solmaz I, Gundogdu S, Keskil S, Sousa RA, Reis RL, Hasirci N, Hasirci V. An In Vivo Study on Effect of Scaffold Geometry and Growth Factor Release on the Healing of Bone Defects. J Tissue Eng Regen Med, 2013;7:687-696.

16. Yilgor C, Yilgor Huri P, Huri G. Tissue Engineering Strategies in Ligament Regeneration. Stem Cells Int 2012, Article ID 374676, doi:10.1155/2012/374676.

17. Yasar U, Yilgor Huri P, Dikmen N. Artificial Blood. Archives Medical Review Journal 2012;21(2):95-108 (Turkish)

18. Invited Review: Demirbag B*, Yilgor Huri P*, Kose GT, Buyuksungur A, Hasirci V. Advanced Cell Therapies with and without Scaffolds. Biotech J 2011;6(12):1437-1453 (*equal contribution).

19. Yilgor P, Sousa RA, Reis RL, Hasirci N, Hasirci V. Effect of Scaffold Architecture and BMP-2/BMP-7 Delivery on in vitro Bone Regeneration. J Mater Sci Mater Med 2010;21:2999-3008.

20. Yilgor P, Hasirci N, Hasirci V. Sequential BMP-2/BMP-7 Delivery from Polyester Nanocapsules. J Biomed Mater Res 2010;93A:528-536.

21. Yilgor Huri P, Hasırcı N, Hasırcı V. Bone Tissue Engineering. Archives Medical Review Journal 2010;19(4):206-219 (Turkish)

22. Yilgor P, Tuzlakoglu K, Reis RL, Hasirci N, Hasirci V. Incorporation of a Sequential BMP-2/BMP-7 Delivery System into Chitosan-Based Scaffolds for Bone Tissue Engineering. Biomaterials 2009;30:3551–3559.

23. Invited Review: Zorlutuna P, Yilgor P, Basmanav FB, Hasirci V. Biomaterials and Tissue Engineering Research in Turkey: The METU BIOMAT Center Experience. Biotech J 2009;4:965-980.

24. Yilgor P, Sousa RA, Reis RL, Hasirci N, Hasirci V. 3D Plotted PCL Scaffolds for Stem Cell Based Bone Tissue Engineering. Macromol Symp 2008;269:92-99.

25. Hasirci V, Vrana E, Zorlutuna P, Ndreu A, Yilgor P, Basmanav B, Aydin E. Nano biomaterials; A review of the existing science and technology, and new approaches. J Biomater Sci Polymer Ed 2006;17(11):1241-1268.

26. Calik P, Yilgor P, Demir AS. Influence of controlled-pH and Uncontrolled-pH operations on recombinant benzaldehyde lyase production by Escherichia coli. Enzym Microb Tech 2006;38(5):617-627.

27. Calik P, Yilgor P, Ayhan P, Demir AS. Oxygen Transfer Effects On Recombinant Benzaldehyde Lyase Production. Chem Eng Sci 2004;59:5075-5083.

 

Book Chapters

1. Yilgor Huri P, Talak E, Grayson WL. Clinical Applications of 3D Printing. In: B. Garipcan, A. Denizli (eds.) Biomaterials and Stem Cells: From Basics to Applications, Palme Yayınevi, 2018.

2. Aktas B, Garipcan B, Ahi ZB, Tuzlakoglu K, Ergene E, Yilgor Huri P. Osteoimmunomodulation with Biomaterials. In: N. E. Vrana, A. Ghaemmagham (eds.) Immune Response to Biomaterials, Chapter 8, CRC Press, in press, 2018.

3. Yilgor Huri P, Gilbert-Honick J, Morrissette-McAlmon J, Somers S, Grayson WL. Myogenic Differentiation of ASCs using Biochemical and Biophysical Induction. In: B. A. Bunnell, J. M. Gimble (eds.) Adipose Derived Stem Cells: Methods and Protocols, Second Edition. Springer, 2018. (ISBN: 978-1-4939-7799-4)

4. Hasirci V, Yilgor Huri P, Endogan T, Eke G, Hasirci N. Polymer Fundamentals: Polymer Synthesis. Chapter 1.22, In: P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick (eds.) Comprehensive Biomaterials 2nd Edition, pp. 478–506, Elsevier, 2017. (Hardcover ISBN: 9780081006917) http://dx.doi.org/10.1016/B978-0-12-803581-8.10208-5

5. Hung BP, Yilgor Huri P, Temple JP, Dorafshar A, Grayson WL. Craniofacial Bone. In: L. G. Zhang, J. P. Fisher (eds.) 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine. Chapter 10, pg 215-230, Elsevier Publishing, 2015. (ISBN: 978-0-12-800547-7)

6. Karakecili A, Tigli Aydin S, Yilgor Huri P. Doku Mühendisliği. In: M. H. Asyalı, S. Kara, B. Yilmaz (Eds.) Biyomedikal Mühendisliğinin Temelleri. Chapter 13, pg 433-475, Nobel Yayınevi, 2014. (978-605-133-943-6)

7. Yilgor Huri P, Temple JP, Hung BP, Cook CA, Grayson WL. Bioreactor Technology for Oral and Craniofacial Tissue Engineering. In: A. Vishwakarma, P. Sharpe, S. Shi, X. Wang, M. Ramalingam (eds.) Stem Cell Biology and Tissue Engineering in Dental Sciences. Part II, Chapter 9, pg 117-130, Elsevier Publishing, 2014. (ISBN: 978-0-12-397157-9) 

8. Yilgor Huri P, Grayson WL. Engineering Functional Bone Grafts for Craniofacial Regeneration. In: L.G. Zhang, A. Khademhosseini, T. Webster (eds.) Tissue and Organ Regeneration: Advances in Micro and Nanotechnology, Chapter 17, pg 589-620, Pan Stanford Publishing, 2014. (ISBN: 978-981-4411-67-7).

9. Hasirci V, Yilgor P, Endogan T, Eke G, Hasirci N. Polymer Fundamentals: Polymer Synthesis. In: P. Ducheyne, K.E. Healy, D.W. Hutmacher, D.W. Grainger, C.J. Kirkpatrick (eds.) Comprehensive Biomaterials, vol. 1, 349-371, Elsevier, 2011. (ISBN: 978-0-08-055294-1)

10. Yilgor P, Yucel D, Kenar H, Hasirci V. Polyhydroxyalkanoates: a Versatile Class of Biopolymers, and Their Biomedical Potential. Brazilian Network Of Green Chemistry: Awareness, Responsibility And Action. Ed. Carioca JOB, Chapter 20,415-431, 2008. (ISBN: 978-85-7282-289-3)

 

Other Publications

1. Yilgor Huri P. Doku Mühendisliği: Laboratuvardan Kliniğe. Ankara Üniversitesi Mühendislik Fakültesi Kurumsal Görüş, 2016. http://www.eng.ankara.edu.tr/kurumsal-gorusler/

2. Yilgor Huri P. Current tissue engineering strategies in orthopaedics show promise. Ortopaedics Today Europe- The Official Newspaper of EFORT, 2015; 18: 4 (April 2015). https://www.healio.com/orthopedics/ biologics/news/print/orthopaedics-today-europe/

 

Administrative Duties:

1. Chair, Ankara University Department of Biomedical Engineering, 2018+  

2. Director, Ankara University Medical Design Research and Application Center, 2018+

3. Vice Chair, Ankara University Department of Biomedical Engineering, 2015+

 

Membership:

1.   International Society for Biofabrication 2018+

2. European Society for Biomaterials (ESB) 2013+

3. Orthopedic Research Society 2012+

4. BIOMATEN Center of Excellence in Biomaterials and Tissue Engineering 2011+

5. Biomaterials and Tissue Engineering Society (Turkey) 2009+

6. Tissue Engineering and Regenerative Medicine International Society 2008+