Name : SİNEM
E-Mail :,
Phone Number : +903122033099
Department : Department of Pharmacognosy
Personal Information



Marital Status: Married with 1 children

Place of birth: Antakya

Date of birth: 23.11.1978

Language: English (fluently)


B.Sc.: 1996-2000 Ankara University Faculty of Pharmacy.

M.Sc.: 2000-2003 Ankara University Faculty of Pharmacy, Department of Pharmacognosy.

Ph.D.: 2003-2009 Ankara University Faculty of Pharmacy, Department of Pharmacognosy.



Research Assistant: 2002-2012 Ankara University Faculty of Pharmacy, Department of Pharmacognosy, Turkey.



PhD. Thesis:

Pharmacognostic Studies on some Eryngium L. Species Growing in Turkey  (2009).


M.Sc. Thesis:

Researches on Terpenic Compounds of Valeriana phu L.  (2003).




§  “Investigation of the effects of the plant species Eryngium kotschyi and Eryngium maritimum grown in Turkey on rat isolated intestine and detrussor smooth muscle by isolated organ bath”  Supported by Ankara University (BAPRO-08B3338003), 2008-2011, Researcher.

§  “Researches on acetylcholinesterase inhibitory activity of Buxus sempervirens L. growing in Turkey” Supported by The Scientific and Technological Research Council of Turkey (TÜBİTAK- (104T492)), 2005-2007, Researcher


Research Interest:

§  GC and GC/MS analysis of essential oils and fatty acids.

§  Isolation of triterpene saponins from plant materials with different chromatographic techniques and structure elucidation of triterpene saponins by 1D and 2D NMR techniques.



§ KAŞKATEPE BANU,Süzük Yıldız Serap,KIYMACI MERVE EYLÜL,YAZGAN AYŞE NUR,Cesur Salih,ASLAN ERDEM SİNEM (2017). Chemical composition and antimicrobial activity of the commercial Origanum onites L. oil against nosocomial carbapenem resistant extended spectrum beta lactamase producer Escherichia coli isolates. Acta Biologica Hungarica, 68(4), 466-476., Doi: 10.1556/018.68.2017.4.11 

§  Mutluay Yayla Ezgi,İZGÜ NUR,ÖZDEMİR LEYLA,ASLAN ERDEM SİNEM,KARTAL MURAT (2016). Sage tea thyme peppermint hydrosol oral rinse reduces chemotherapy induced oral mucositis A randomized controlled pilot study. Complementary Therapies in Medicine, 27, 58-64., Doi: 10.1016/j.ctim.2016.05.010

 § ASLAN ERDEM SİNEM,ARIHAN OKAN,Mitaine Offer Anne Claire,İSKİT ALPER BEKTAŞ,KARTAL MURAT,Lacaille Dubois Marie Aleth (2016). Antinociceptive Effects of Turkish Endemic Eryngium kotschyi Boiss Roots by Bioactivity Guided Fractionation. Records of Natural Products, 10(2), 168-175.

§ KAŞKATEPE BANU,KIYMACI MERVE EYLÜL,Süzük Serap,ASLAN ERDEM SİNEM,Cesur Salih,YILDIZ SULHİYE (2016). Antibacterial effects of cinnamon oil against carbapenem resistant nosocomial Acinetobacter baumannii and Pseudomonas aeruginosa isolates. Industrial Crops and Products, 81, 191-194., Doi: 10.1016/j.indcrop.2015.11.058

 § ASLAN ERDEM SİNEM,ŞENOL FATMA SEZER,Budakoğlu Esin,ERDOĞAN ORHAN İLKAY,ŞENER BİLGE (2016). Exploring in vitro neurobiological effects and high pressure liquid chromatography assisted quantitation of chlorogenic acid in 18 Turkish coffee brands. Journal of Food and Drug Analysis, 24(1), 112-120., Doi: 10.1016/j.jfda.2015.08.001

 § Orhan Ilkay Erdogan,Senol Fatma Sezer,ASLAN ERDEM SİNEM,Tatli I Irem,KARTAL MURAT,Alp Sevket (2015). Tyrosinase and Cholinesterase Inhibitory Potential and Flavonoid Characterization of Viola odorata L Sweet Violet. Phytotherapy Research, 29(9), 1304-1310., Doi: 10.1002/ptr.5378

§ ASLAN ERDEM SİNEM,Mitaine-Offer Anne-Claire,Miyamoto Tomofumi,KARTAL MURAT,Lacaille- Dubois Marie-Aleth (2015). Triterpene saponins from Eryngium kotschyi. Phytochemistry, 110, 160-165., Doi: 10.1016/j.phytochem.2014.11.017 

 § Erdogan Orhan, I., Guner, E., Ozturk, N., Senol, F.S., Aslan Erdem, S., Kartal, M., Sener, B. (2012). Enzyme inhibitory and antioxidant activity of Melia azedarach L. naturalized in Anatolia and its phenolic acid and fatty acid composition. Industrial Crops and Products. 37: 213-218.

§  Orhan, İ.E., Khan, M.T.H., Aslan Erdem, S., Kartal, M., Şener, B. (2011). Selective cholinesterase inhibitors from Buxus sempervirens L. and their molecular docking studies. Current Computer-Aided Drug Design. 7: 276-286.

§  Senol, Fatma Sezer; Orhan, Ilkay Erdogan; Erdem, Sinem Aslan; Kartal, Murat; Sener, Bilge; Kan, Yuksel; Celep, Ferhat; Kahraman, Ahmet; Dogan, Musa. (2011). Evaluation of Cholinesterase Inhibitory and Antioxidant Activities of Wild and Cultivated Samples of Sage (Salvia fruticosa) by Activity-Guided Fractionation. Journal of Medicinal Food, 14(11), 1476-1483.

§  Kilic, Ceyda Sibel; Aslan, Sinem; Kartal, Murat; Coskun, Maksut. (2011). Fatty acid composition of Hibiscus trionum L. (Malvaceae). Records of Natural Products, 5(1), 65-69.

§  Ugur, Atnan; Suntar, Ipek; Aslan, Sinem; Orhan, Ilkay Erdogan; Kartal, Murat; Sekeroglu, Nazim; Esiyok, Dursun; Sener, Bilge. (2010). Variations in fatty acid compositions of the seed oil of Eruca sativa Mill. caused by different sowing periods and nitrogen forms. Pharmacognosy Magazine, 6(24), 305-308.

§  Ozbay, Ozge; Aslan, Sinem; Kartal, Murat; Kurucu, Semra; Bos, Rein; Woerdenbag, Herman J.; Kayser, Oliver. (2009). Preliminary examination of the composition of the essential oil from the roots and rhizomes of Valeriana alpestris Stev. growing in Turkey. Journal of Essential Oil Research, 21(6), 555-557.

§  Aslan, Sinem; Kartal, Murat; Kurucu, Semra; Kuiper, Johanna M.; Kruzinga, Wim H.; Bos, Rein; Woerdenbag, Herman J.; Kayser, Oliver. (2009). Composition of the essential oil from roots and rhizomes of Valeriana phu L. growing wild in Turkey. Journal of Essential Oil Research, 21(5), 437-440.

§  Aslan, S., Evren, H., Konuklugil, B., Turkoglu, I., Kartal, M. (2009). Essential oil composition of Achillea teretifolia from Turkey. Chemistry of Natural Compounds. 45(2): 274-275.

§  Orhan, İlkay; Özçelik, Berrin; Aslan, Sinem; Kartal, Murat; Karaoglu, Taner; Sener, Bilge; Terzioglu, Salih; Choudhary, M. Iqbal. (2009). In vitro biological activity screening of Lycopodium complanatum L. ssp. chamaecyparissus (A. Br.) Doll. Natural Product Research, Part A: Structure and Synthesis. 23(6): 514-526.

§  Mehmood, Sajid; Orhan, İlkay; Ahsan, Zaheer; Aslan, Sinem; Gulfraz, Muhammad. (2008).Fatty acid composition of seed oil of different Sorghum bicolor varieties. Food Chemistry. 109(4): 855-859.

§  Orhan, İlkay; Aslan, Sinem; Kartal, Murat; Şener, Bilge; Hüsnü Can Başer, K. (2008). Inhibitory effect of Turkish Rosmarinus officinalis L. on acetylcholinesterase and butyrylcholinesterase enzymes. Food Chemistry. 108(2): 663-668.

§  Aslan, Sinem; Fırat, Mehmet; Konuklugil, Belma. (2007). Essential oil of Cyclotrichium longiflorum Leblebici. Chemistry of Natural Compounds. 43(6): 724-725.

§  Orhan, İlkay; Özçelik, Berrin; Aslan, Sinem; Kartal, Murat; Karaoğlu, Taner; Şener, Bilge; Terzioğlu, Salih; Choudhary, M. Iqbal. (2007).Antioxidant and antimicrobial actions of the clubmoss Lycopodium clavatum L. Phytochemistry Reviews. 6(1): 189-196.

§  Şener, Bilge; Orhan, İlkay; Özçelik, Berrin; Kartal, Murat; Aslan, Sinem; Özbilen, Gamze. (2007). Antimicrobial and antiviral activities of 2 seed oil samples of Cucurbita pepo L. and their fatty acid analysis. Natural Product Communications. 2(4): 395-398.

§  Küpeli Esra; Kartal Murat; Aslan Sinem; Yeşilada Erdem. (2006). Comparative evaluation of the anti-inflammatory and antinociceptive activity of Turkish Eryngium species. Journal of Ethnopharmacology. 107(1): 32-7.

§  Orhan, İlkay; Özçelik, Berrin; Kartal, Murat; Aslan, Sinem; Şener, Bilge; Özgüven, Menşure. (2007). Quantification of daidzein, genistein and fatty acids in soybeans and soy sprouts, and some bioactivity studies. Acta Biologica Cracoviensia Series Botanica. 49(2): 61-68.

§  Kan, Yüksel; Uçan, Uçkun Sait; Kartal, Murat; Altun, M. Levent; Aslan, Sinem; Sayar, Esin; Ceyhan, Timurhan. (2006) GC-MS analysis and antibacterial activity of cultivated Satureja cuneifolia Ten. essential oil. Turkish Journal of Chemistry. 30(2): 253-259.

§  Kan, Yüksel; Orhan, İlkay; Koca, Ufuk; Özçelik, Berrin; Aslan, Sinem; Kartal, Murat; Küsmenoğlu, Şenay. (2009). Fatty acid profile and antimicrobial effect of the seed oils of Urtica dioica and U. pilulifera. Turkish Journal of Pharmaceutical Sciences. 6(1): 21-30.

§  Orhan, İlkay; Koca, Ufuk; Aslan, Sinem; Kartal, Murat; Küsmenoğlu, Şenay. (2008). Fatty acid analysis of some Turkish apricot seed oils by GC and GC-MS techniques. Turkish Journal of Pharmaceutical Sciences. 5(1): 29-34.

§  Kılıç, Ceyda Sibel; Aslan, Sinem; Kartal, Murat; Coşkun, Maksut. (2007). Comparison of the fixed oil of seeds and roots of Capsella bursa-pastoris (L.) Medik (Cruciferae). Ankara Üniversitesi Eczacılık Fakültesi Dergisi. 36(1): 1-7.

§  Kan, Yüksel; Kartal, Murat; Özek, Temel; Aslan, Sinem; Başer, K. Hüsnü Can. (2007).Composition of essential oil of Cuminum cyminum L. according to harvesting times. Turkish Journal of Pharmaceutical Sciences.  4(1): 25-29.

§  Kan, Yüksel; Kartal, Murat; Aslan, Sinem; Yıldırım, Nilüfer. (2006),.Composition of essential oil of fennel fruits cultivated under different conditions. Ankara Üniversitesi Eczacılık Fakültesi Dergisi. 35(2): 95-101.

§  Kan, Yuksel; Kan, Asuman; Ceyhan, Timurhan; Sayar, Esin; Kartal, Murat; Altun, Levent; Aslan, Sinem; Cevheroğlu, Şemsettin. (2005). Atomic absorption spectrometric analysis of Trigonella foenum-graecum L. seeds cultivated in Turkey. Turkish Journal of Pharmaceutical Sciences. 2(3): 187-191.

§  Kartal, Murat; Kurucu, Semra; Aslan, Sinem; Özbay, Özge; Ceyhan, Timurhan; Sayar, Esin; Cevheroğlu, Şemsettin. (2003). Comparison of o-3 fatty acids by GC-MS in frequently consumed fish and fish oil preparations on the Turkish market. FABAD Journal of Pharmaceutical Sciences.  28(4): 201-205.