PROF.DR. SİBEL SÜZEN    
Name : SİBEL
Surname : SÜZEN
E-Mail : sibel@pharmacy.ankara.edu.tr, sibel2264@gmail.com
Phone Number : 2033074
Title : PROF.DR.
Unit : FACULTY OF PHARMACY
Department : Pharmaceutical Chemistry
Personal Information

Current Position                   : Professor of Pharmaceutical Chemistry

Address                                 : Ankara University Faculty of Pharmacy

                                                 Department of Pharmaceutical Chemistry

                                                 06100 Tandogan, Ankara, Turkey

E-Mail                                    : sibel@pharmacy.ankara.edu.tr  ; sibel2264@gmail.com

URL:                                     :http://cv.ankara.edu.tr/sibel@pharmacy.ankara.edu.tr

Tel                                          : +90 312 22033074
Fax                                         : +90 312 213 1081

Mobil                                      : 0533 3915844

Foreign Language:  English (Advanced fluent speaking and writing)                                                                                               

European Administrative Charges 

EDQM: Eur Farmacopea expert, Group 10D (Semi synthetic-synthetic compounds) (2011-  )

EU Educational Programs and Institutional Erasmus Coordinator of Ankara University (2012-  )

Internationalization Coordinator of Ankara University (2015- )

International Student’s Coordinator of Ankara University (2015- )

Mevlana Exchange Programme Coordinator of Ankara University (2018- )

 Education                                                                                                  

Phd Degree:                         University of Swansea, Chemistry Department, UK, (1997)

MSc Degree:                         Ankara University, Faculty of Pharmacy, Department of  

   Pharmaceutical Chemistry, Turkey (1990)

Bachelor's degree:              Ankara University, Faculty of Pharmacy, Turkey (1985)

 

Academical Background

2008                            Full Professor at Ankara University, Faculty of Pharmacy,
                                    Department of Pharmaceutical Chemistry
2002                            Associate Professor at Ankara University, Faculty of Pharmacy,                                                
Department of Pharmaceutical Chemistry

2000                            Assistant Professor at Ankara University, Faculty of Pharmacy,
                                    Department of Pharmaceutical Chemistry

1997                            PhD, University of Swansea, Chemistry Department, UK

1989                            Master Degree, Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry

1985                            Ankara University, Faculty of Pharmacy

 

Projects

Design and synthesis of aldose reductase inhibitors and in-vitro/in-vivo evaluation of enzyme activities (Ankara Univ. Research Found 88.03.00.01), (1988).

Effects of retinoidal benzimidazoles on free radicals and lipid peroxidation (TUBITAK Project SBAG-AYD-44), (1990).

Synthesis of new compounds against radiation and biological evaluation (Ankara Univ. Research Found 99.03.00.03), (1999).

Synthesis and antioxidant activity studies of melatonin derivatives against radiation (Ankara Univ. Research Found 2001-08-03-09), (2001)

Electroanalitical investigation of some antiviral and antibacterial drugs (Ankara Univ. Research Found 20030803037), (2003)

Synthesis and biological evaluation of aldose reductase inhibitor compounds (Ankara Univ. Research Found 20050803051), (2005)

Analysis of phytoestrogens  in plants TUBITAK Proje 108S202 (SBAG-4039), (Ankara-2008)

Development of New Melatonin Analogue Antioxidant drugs: Evaluation of Biological Activity, Cytotoxicity and in-vitro metabolites by electrochemistry (Tübitak 109S099), (2009)

Development of Indole and carbazole derivative drug active substances: Evaluation of antioxidant and chemopreventive activity in cancer. (Tübitak 112S599), (2013)

Investigation of mechanisms of estrogen carcinogenesis as target for anticancer drugs.  (Tübitak 117S065) (2017)

 

Books/Chapters 

1. Gurer Orhan H, Suzen S, Csont TB, Pohanka M, Nejman-Falenczyk B, Wegrzyn G, Saso.          L. In Vitro Methods for the Evaluation of Oxidative Stress Pp. 131-172 (42) Book: Recent           Advances in Analytical Techniques Vol. 2 Novel Developments in Pharmaceutical and             Biomedical Analysis. http://ebooks.benthamscience.com/book/9781681085746; DOI: 10.2174/97816810857461180201, 2018

2. Suzen S. Melatonin and Its Antiaging Activity: New Approaches and Strategies for Age-Related Disorders. Book: Molecular Basis and Emerging Strategies for Anti-aging Interventions, Rizvi, Syed Ibrahim, Çakatay, Ufuk (Eds.), Pages 217-235, Springer,  ISBN 978-981-13-1699-9, 2018

3. Suzen S. Evaluation of synthetic melatonin analogue antioxidant compounds. Book: Melatonin: Therapeutic Value and Neuroprotection. Srinivasan V, Gobbi G, Shillcutt S.D, Suzen S (Eds). Publisher: Boca Raton: Taylor & Francis, (2015), Chapter 21, p. 259-269. ISBN: 9781482220100 1482220105

4. Electroanalytical Methods in Pharmaceutical Analysis and Their Validation. Ed. Ozkan, S.A., Medicinal and Pharmaceutical Applications and prospects of Electrochemistry, Suzen, S., and Ozkan, S.A. ISBN: 978-0-9664286-7-4, NHB Publishing, 2010.

5. Suzen S. Topics in Heterocyclic Chemistry, Bioactive Heterocycles V,  Chapter : “Antioxidant Activities of Synthetic Indole Derivatives and Possible Activity Mechanisms”,  Khan, M.T.H. (Ed.), Vol. 11 Page 145-178 (2007) Spinger-Verlag Berlin Heidelberg.

6. Ozden S, Ertan R, Akı-Sener E, Yalcın I, Nebioglu D, Buyukbingol E, Goker H, Yıldız I, Altuntas-Dinlenc TG, Tuncbilek M, Ayhan-Kılcıgil G, Olgen S, Suzen S, Temiz-Arpacı O, Kus C, Bozdag-Dundar O, Tekiner-Gülbas B, Ates-Alagoz Z. A.Ü Eczacılık Fakültesi “Farmasötik Kimya Pratikleri 1-2” Uygulama kitabı (Pharmaceutical Chemistry Practise 1-2 Lab. Book)  ISBN 975-482-649-8 A.Ü Basımevi, 2004.

7. Ozden S, Ertan R, Akı-Sener E, Yalcın I, Nebioglu D, Buyukbingol E, Goker H, Yıldız I, Altuntas-Dinlenc TG, Tuncbilek M, Ayhan-Kılcıgil G, Olgen S, Suzen S, Temiz-Arpacı O, Kus C, Bozdag-Dundar O, Tekiner-Gülbas B, Ates-Alagoz Z. A.Ü Eczacılık Fakültesi “Farmasötik Kimya Pratikleri 3-4” Uygulama kitabı (Pharmaceutical Chemistry Practise 3-4 Lab. Book)  ISBN 975-482-649-8 A.Ü Basımevi, 2004.

 

Editorial Board Member

Enzyme Inhibition and Medicinal Chemistry (2009-   )

Journal of Pharmaceutics (2011- 2017)

Current Enzyme Inhibition (2015-2018) 

Guest Editor 

Saso L, Kukreti R, Suzen S. Modulation of Oxidative Stress: Molecular and Pharmacological Aspects. Int J Mol Sci (ISSN 1422-0067). 2019, This special issue belongs to the section "Molecular Pharmacology".

Suzen SSaso L. Organic compounds as modulators of oxidative stress:
chemical and biological aspects. Curr Org Chem. 2017:21(20):2029

 Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological target for medicinal chemistry: synthesis and evaluation of compounds with redox activity.Part 4.  Curr Top Med Chem. 2015;15(9):821

 Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological target for medicinal chemistry: synthesis and evaluation of compounds with redox activity.Part 3. Curr Top Med Chem. 2015;15(5):414. 

 Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological target for medicinal chemistry: synthesis and evaluation of compounds with redox activity.Part 2. Curr Top Med Chem. 2015;15(2):84.

 Borges F, Garrido J, Saso L, Suzen S. Oxidative stress as a pharmacological target for medicinal chemistry: synthesis and evaluation of compounds with redox activity.  Part 1. Curr Top Med Chem. 2014;14(22):2461 

Borges F, Saso L, Garrido J, Suzen S. Synthesis, evaluation and pharmacological applications of antioxidants- Part 1. Curr Med Chem. 2013;20(36):4435.

 Borges F, Saso L, Garrido J, Suzen S. Synthesis, evaluation and pharmacological applications of antioxidants- Part 2. Curr Med Chem. 2013;20(36):4435

 Suzen S, Saso L. Editorial: antioxidant heterocyclic compounds in drug discovery and medicinal chemistry. Mini Rev Med Chem. 2013 Mar;13(3):317.

 Suzen, S. Combinatorial Chemistry and High Throughput Screening: Editorial (2006) Combinatorial Chemistry and High Throughput Screening, 9 (6), 407.

 International Publications  (SCI / SCI expanded)

Karaaslan C, Ince E, Gurer-Orhan H, Tavakkoli M, Firuzi O, Saso L, Suzen S. Behaviour of 9-ethyl-9_H_-carbazole hydrazone derivatives against oxidant systems: protective effect on amyloid β-induced damage. (2019) Croat Chem Acta, In Print

Telkoparan-Akillilar P, Suzen S, Saso S. Pharmacological Applications of Nrf2 Inhibitors as Potential Antineoplastic Drugs. (2019) Int J Molecular Sci (IJMS), (ISSN 1422-0067), In print

 Hilgeroth A, Yasrebi K, Suzen S, Hertlein T, Ohlsen K, Lalk M. Antibacterial Evaluation  of Novel Substituted Cycloheptaindoles in Staphylococcus and Enterococcus strains. (2019) Med Chem. Feb 8. doi: 10.2174/1573406415666190208170126. [Epub ahead of print]

 Ozcan-Sezer S, Ince E, Akdemir A, Ceylan ÖÖ, Suzen S, Gurer-Orhan H. Aromatase inhibition by 2-methyl indole hydrazone derivatives evaluated via molecular docking and in vitro activity studies. (2019) Xenobiotica. May;49(5):549-556. doi: 10.1080/00498254.2018.1482029. Epub 2018 Sep 12.

 Gurer-Orhan H, Ince E, Konyar D, Saso L, Suzen S. The Role of Oxidative Stress Modulators In Breast Cancer. (2018) Curr Med Chem. 25(33):4084-4101.

 Suzen, S. Recent Studies and Biological Aspects of Substantial Indole Derivatives with Anticancer Activity (2017) Curr Org Chem. 20(21) 2068 – 2076.

 Suzen S, Gurer-Orhan H, Saso L. Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique. (2017) Molecules. 22(1), pii: E181.

 

Shirinzadeh H, Ince E, Westwell AD, Gurer-Orhan H, Suzen S. Novel indole-based melatonin analogues substituted with triazole, thiadiazole and carbothioamides: studies on their antioxidant, chemopreventive and cytotoxic activities.(2016) J Enzyme Inhib Med Chem. 31(6),1312-21.

 Gurer-Orhan H, Karaaslan C, Ozcan S,  Firuzi O, Tavakkoli M, Saso L, Suzen S. Novel indole-based melatonin analogues: Evaluation of antioxidant activity and protective effect against amyloid β-induced damage. (2016) Bioorg Med Chem. 24(8):1658-64

 El-Sayed Mt,  Zoraghı R, Reıner N, Suzen S,  Ohlsen K, Altanlar N, Hılgeroth A.  Novel inhibitors of the MRSA-pyruvate kinase. (2016) J Enzyme Inh Med Chem.,  31(6):1666-71

 El-Sayed Mt, Suzen S, Altanlar N, Ohlsen K, Hılgeroth A. Discovery of Bisindolyl-Substituted Cycloalkane-Anellated Indoles as Novel Class of Antibacterial Agents against S. aureus and MRSA. (2016) Bioorg Med Chem Lett. 26(1), 218-21.

 Püsküllü, M.O., Shirinzadeh, H., Nenni, M., Gurer-Orhan, H., Suzen, S. Synthesis and evaluation of antioxidant activity of new quinoline-2-carbaldehyde hydrazone derivatives: Bioisosteric Melatonin Analogues. (2016) J Enzyme Inh Med Chem, 31(1):121-5.

 Gurer-Orhan H, Suzen S. Melatonin, its metabolites and its synthetic analogs as multi-faceted compounds: antioxidant, prooxidant and inhibitor of bioactivation reactions. (2015) Curr Med Chem. 22(4), 490-9.

 

Karaaslan C, Suzen S. Antioxidant properties of melatonin and its potential action in diseases. (2015) Curr Top Med Chem. 15(9), 894-903.

 Suzen S, Saso L. Antioxidant heterocyclic compounds in drug discovery and medicinal chemistry. (2013) Mini Rev Med. Chem, 13(3), 317,

 Tekiner-Gulbas, B., Westwell, A.D., Suzen, S. Oxidative stress in carcinogenesis: New synthetic compounds with dual effects upon free radicals and cancer. (2013) Curr Med Chem, 20 (36), pp. 4451-4459.

 Suzen, S., Tekiner-Gulbas, B., Shirinzadeh, H., Uslu, D., Gurer-Orhan, H., Gumustas, M., Ozkan, S.A. Antioxidant activity of indole-based melatonin analogues in erythrocytes and their voltammetric characterization (2013) J Enzyme Inh Med Chem, 28 (6), pp. 1143-1155.

 Püsküllü, M.O., Tekiner, B., Suzen, S. Recent studies of antioxidant quinoline derivatives (2013) Mini-Rev Med Chem, 13 (3), pp. 365-372.

 Karaaslan, C., Kadri, H., Coban, T., Suzen, S., Westwell, A.D. Synthesis and antioxidant properties of substituted 2-phenyl-1H-indoles (2013) Bioorg Med Chem Lett, 23 (9), pp. 2671-2674.

 Suzen, S. Melatonin and synthetic analogs as antioxidants. (2013) Current Drug Delivery, 10 (1), pp. 71-75.

 Yilmaz, A.D., Coban, T., Suzen, S. Synthesis and antioxidant activity evaluations of melatonin-based analogue indole-hydrazide/hydrazone derivatives (2012) Journal of Enzyme Inhibition and Medicinal Chemistry, 27 (3), pp. 428-436.

 Suzen, S., Cihaner, S.S., Coban, T. Synthesis and comparison of antioxidant properties of indole-based melatonin analogue indole amino acid derivatives (2012) Chemical Biology and Drug Design, 79 (1), pp. 76-83.

 Shirinzadeh, H., Altanlar, N., Yucel, N., Ozden, S., Suzen, S. Antimicrobial evaluation of indole-containing hydrazone derivatives (2011) Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 66 C (7-8), pp. 340-344.

 Das-Evcimen, N., Sarikaya, M., Gurkok, G., Suzen, S. Evaluation of rat kidney aldose reductase inhibitory activity of some N-acetyl dehydroalanine derivatives (2011) Medicinal Chemistry Research, 20 (4), pp. 453-460.

 Yuksel, N., Baykara, M., Shirinzade, H., Suzen, S. Investigation of triacetin effect on indomethacin release from poly(methyl methacrylate) microspheres: Evaluation of interactions using FT-IR and NMR spectroscopies (2011) International Journal of Pharmaceutics, 404 (1-2), pp. 102-109.

 Suzen, S., Ozkan, S.A. Combination of electrochemical, spectrometric and other analytical techniques for high throughput screening of pharmaceutically active compounds (2010) Combinatorial Chemistry and High Throughput Screening, 13 (7), pp. 658-664.

 Shirinzadeh, H., Yilmaz, A.D., Gumustas, M., Suzen, S., Ozden, S., Ozkan, S.A. Electrochemical behavior of indole-3-carboxaldehyde izonicotinoyl hydrazones: Discussion on possible biological behavior (2010) Combinatorial Chemistry and High Throughput Screening, 13 (7), pp. 619-627.

 Shirinzadeh, H., Eren, B., Gurer-Orhan, H., Suzen, S., Özden, S. Novel indole-based analogs of melatonin: Synthesis and in vitro antioxidant activity studies (2010) Molecules, 15 (4), pp. 2187-2202.

 Daş-Evcimen, N., Yildirim, O., Suzen, S. Relationship between aldose reductase and superoxide dismutase inhibition capacities of indole-based analogs of melatonin derivatives (2009) Archives of Biological Sciences, 61 (4), pp. 675-681.

 Ferreira, P.M., Monteiro, L.S., Coban, T., Suzen, S. Comparative effect of N-substituted dehydroamino acids and alpha-tocopherol on rat liver lipid peroxidation activities. (2009) Journal of enzyme inhibition and medicinal chemistry, 24 (4), pp. 967-971.

 Gürkök, G., Coban, T., Suzen, S. Melatonin analogue new indole hydrazide/hydrazone derivatives with antioxidant behavior: Synthesis and structureactivity relationships (2009) Journal of Enzyme Inhibition and Medicinal Chemistry, 24 (2), pp. 506-515.

 Gurkok, G., Altanlar, N., Suzen, S. Investigation of antimicrobial activities of indole-3-aldehyde hydrazide/hydrazone derivatives (2009) Chemotherapy, 55 (1), pp. 15-19.

 Çalişkan-Ergün, B., Şüküroǧlu, M., Coban, T., Banoǧlu, E., Suzen, S. Screening and evaluation of antioxidant activity of some pyridazine derivatives (2008) Journal of Enzyme Inhibition and Medicinal Chemistry, 23 (2), pp. 225-229.

 Suzen, S., Das-Evcimen, N., Varol, P., Sarikaya, M. Preliminary evaluation of rat kidney aldose reductase inhibitory activity of 2-phenylindole derivatives: Affiliation to antioxidant activity (2007) Medicinal Chemistry Research, 16 (3), pp. 112-118.

 Şüküroǧlu, M., Çalişkan-Ergün, B., Das-Evcimen, N., Sarikaya, M., Banoǧlu, E., Suzen, S. Screening and evaluation of rat kidney aldose reductase inhibitory activity of some pyridazine derivatives (2007) Medicinal Chemistry Research, 15 (7-8), pp. 443-451.

 Suzen, S., Bozkaya, P., Coban, T., Nebioǧlu, D. Investigation of the in vitro antioxidant behaviour of some 2-phenylindole derivatives: Discussion on possible antioxidant mechanisms and comparison with melatonin (2006) Journal of Enzyme Inhibition and Medicinal Chemistry, 21 (4), pp. 405-411.

 Suzen, S. Recent developments of melatonin related antioxidant compounds (2006) Combinatorial Chemistry and High Throughput Screening, 9 (6), pp. 409-419.

 Suzen, S., Gurkok, G., Coban, T. Novel N-acyl dehydroalanine derivatives as antioxidants: Studies on rat liver lipid peroxidation levels and DPPH free radical scavenging activity (2006) Journal of Enzyme Inhibition and Medicinal Chemistry, 21 (2), pp. 179-185.

 Gurer-Orhan, H., Orhan, H., Suzen, S., Püsküllü, M.O., Buyukbingol, E. Synthesis and evaluation of in vitro antioxidant capacities of some benzimidazole derivatives (2006) Journal of Enzyme Inhibition and Medicinal Chemistry, 21 (2), pp. 241-247.

 Ateş-Alagöz, Z., Coban, T., Suzen, S. A comparative study: Evaluation of antioxidant activity of melatonin and some indole derivatives (2005) Medicinal Chemistry Research, 14 (3), pp. 169-179.

 Kaymakçioǧlu, B.K., Aktan, Y., Süzen, S., Gökhan, N., Koyunoǧlu, S., Erol, K., Yeşilada, A., Rollas, S. In vivo metabolism of 2-[1′-phenyl-3′-(3-chlorophenyl)- 2′-propenylyden]hydrazino-3-methyl-4(3H)-quinazolinone in rats (2005) European Journal of Drug Metabolism and Pharmacokinetics, 30 (4), pp. 255-260.

 Dogan, B., Uslu, B., Suzen, S., Ozkan, S.A. Electrochemical evaluation of nucleoside analogue lamivudine in pharmaceutical dosage forms and human serum (2005) Electroanalysis, 17 (20), pp. 1886-1894.

 Suzen, S., Buyukbingol, E. Recent studies of aldose reductase enzyme inhibition for diabetic complications (2003) Current Medicinal Chemistry, 10 (15), pp. 1329-1352.

 Süzen, S., Demírcígíl, B.T., Buyukbingol, E., Özkan, S.A. Electroanalytical evaluation and determination of 5-(3′-indolyl)-2-thiohydantoin derivatives by voltammetric studies: Possible relevance to in vitro metabolism (2003) New Journal of Chemistry, 27 (6), pp. 1007-1011.

 Süzen, S., Ateş-Alagöz, Z., Demircigil, B.T., Özkan, S.A. Synthesis and analytical evaluation by voltammetric studies of some new indole-3-propionamide derivatives (2001) Farmaco, 56 (11), pp. 835-840.

 Göker, H., Tunçbilek, M., Süzen, S., Kus, C., Altanlar, N. Synthesis and antimicrobial activity of some new 2-phenyl-N-substituted carboxamido-1H-benzimidazole derivatives (2001) Archiv der Pharmazie, 334 (5), pp. 148-152.

 Kendi, E., Ates-Alagoz, Z., Suzen, S., Buyukbingol, E. Crystal structure of 2-[(5′,6′,7′,8′-tetrahydro-5′,5′ ,8′,8′-tetramethyl)-2′-naphthyl] -1-ethyl-1H-benzimidazole-5-carboxylic acid ethyl ester (2001) Analytical Sciences, 17 (4), pp. 567-568.

 Göker, H., Süzen, S., Kuş, C., Boykin, D.W. Synthesis of new 2-aryl-4H-4-oxo-1-benzopyran oxime ethers (2000) Heterocyclic Communications, 6 (5), pp. 385-390.

 Süzen, S., Williams, J.M. Investigation of the synthesis of some dehydroalanine derivatives (2000) Turkish Journal of Chemistry, 24 (4), pp. 361-370.

 Suzen, S., Buyukbingol, E. Anti-cancer activity studies of indolalthiohydantoin (PIT) on certain cancer cell lines (2000) Farmaco, 55 (4), pp. 246-248.

 Ates-Alagoz, Z., Suzen, S., Buyukbingol, E., Caira, M.R. Synthesis and structure of 2-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalene)]-5-benzimidazole ethylcarboxylate monohydrate (2000) Journal of Chemical Crystallography, 30 (2), pp. 103-107.

 Suzen, S., Williams, M. Behaviour of dehydroalanine derivatives under hydrazinolysis conditions. Possible relevance to glycoprotein hydrazinolysis (1999) Journal of Peptide Science, 5 (6), pp. 283-286.

 Suzen, S., Buyukbingol, E. Evaluation of anti-HIV activity of 5-(2-phenyl-3'-indolal)-2 thiohydantoin (1998) Farmaco, 53 (7), pp. 525-527.

 Evcimen, N.D., Pekiner, B., Süzen, S., Büyükbingöl, E. The inhibitory effect of benzodiazepine derivatives on the bovine lens aldose reductase enzyme (1998) Biochemistry and Molecular Biology International, 45 (2), pp. 381-387.

 Ates, Z., Suzen, S., Buyukbingol, E. Effects of a benzimidazole compound on monooxygenase activities (1997) Farmaco, 52 (11), pp. 703-706.

 Buyukbingol, E., Suzen, S., Klopman, G. Studies on the synthesis and structure-activity relationships of 5-(3'- indolal)-2-thiohydantoin derivatives as aldose reductase enzyme inhibitors (1994) Farmaco, 49 (6), pp. 443-447.

 Publications with other international indexed journals

 Shirinzadeh H, Suzen S.Altanlar N, Westwell AD. Antimicrobial activities of new indole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole and carbothioamide. (2018) Turkish J Pharm Sci, 15(3), 291-297 (Web of Science-Emerging Sources Citation Index (ESCI))

 Yılmaz, A.D., Karaaslan, C., Shirinzadeh, H., Suzen, S., Ozcan, S., Gurer Orhan, H. New Antioxidant Drug Development Studies on Neurohormone Melatonin and Synthetic Analogues. (2014) Academic Journal of Science. 3(2), 51-56. (Index Copernicus)

 Karaaslan, C., Suzen S. Electrochemical Behavior of Biologically Important Indole Derivatives, (2011) J Int. Electrochemistry, 2011, 1-10 (Expanded Academic Index, Chemical Abstracts Service (CAS), Directory of Open Access Journals (DOAJ))

 Conference Proceedings

 Gurer-Orhan H,Ozcan S, Shirinzadeh H, Suzen, S. Targets for anticancer drugs in estrogen-induced carcinogenesis. (2017) Toxicology Letters 280:S307

Sezer, O., Ince, E., Ozturk-Ceylan, O., Akdermir, A., Suzen, S., Gurer-Orhan H. Design, synthesis and investigation of dual benefits of 2-methyl indole derivatives in hormone-dependent breast cancer: Aromatase inhibitory and antioxidant activity (2016) Toxicology Letters 258:S126

Suzen, S., Shirinzadeh, H., Karaaslan, C., Gurer-Orhan, H., Eren, B. Synthesis and in vitro antioxidant activity studies of melatonin analogue compounds. (2016) Toxicology Letters 258:S202.

 Suzen, S., Yilmaz, A.D., Karaaslan, C., Shirinzadeh, H., Coban, T. Indole-based melatonin analogue compounds as cellular ROS inhibitors: Investigation on the peroxidation of human erythrocyte membranes and oxidative hemolysis (2016) Toxicology Letters 258:S202-S203

 Yılmaz, A.D., Karaaslan, C., Shirinzadeh, H., Suzen, S., Ozcan, S., Gurer Orhan, H. New Antioxidant Drug Development Studies on Neurohormone Melatonin and Synthetic Analogues. (2014) Acad J Sci. 3(2), 51-56. (Index Copernicus)

 Ozcan, S., Uslu, D., Karaaslan, C., Shrınzadeh, H., Suzen, S., Gurer-Orhan, H. Comparision of antioxidant activities of newly synthesized melatonin analogues. (2013) Toxicology Letters 221S, S59–S256 .

 Yılmaz, A.D., Shirinzadeh, H., Coban, T., Suzen, S., Ozden, S. Synthesis and antioxidant activity evaluations of melatonin based analogue indole-hydrazide/hydrazone derivatives. (2012) BMC Proceedings 6(Suppl 4):P28. doi:10.1186/1753-6561-6-S4-P28

 Shirinzadeh, H., Yılmaz, AD., Yücel, N., Altanlar, N., Suzen, S., Ozden, S. Antimicrobial activity of indole-based melatonin analogues .(2012) BMC Proceedings  6(Suppl 4):P27. doi:10.1186/1753-6561-6-S4-P27

 Ozturk, D., Suzen, S., Sabuncuoglu, B., Akkus, B. Radioprotection of the Rat Kidney with a New Indole Based Compound. (2005) Int J Rad Oncol Biol Phys 63(2) Suppl 1, S437. DOI: http://dx.doi.org/10.1016/j.ijrobp.2005.07.746

Publications in National Journals

 Das-Evcımen N, Sarıkaya M, Karaaslan C, Yılmaz Ad, Shırınzadeh H, Suzen S. Rat Lung Aldose Reductase Inhibition Capacity of Substituted Indole Hydrazide/Hydrazone Derivatives. FABAD J.Pharm. Sci., 37(4), 169-174, 2012

 Karaaslan C., Suzen, S. Mucize Hormon Melatonin Hakkında Bilinmesi Gerekenler. (2012) Modern Fitofarmakoterapi ve Doğal Farmasötikler, 1, 30-36

 Ozturk D, Sabuncuoglu B, Suzen S, Akkus-Yıldırım B. İndol türevi yeni bir bileşik ile sıçanlarda radyasyon nefropatisinin engellenmesi (The prevention of radiation nephropaty in the rat with a new ındol based compound) (2004) Cumhuriyet Üniv. Tıp Fak. Dergisi., 26(3), 107-112.

 Ateş Alagöz, Z., Süzen, S. Oxidative damage in the central nervous system and protection by melatoni̇n [Santral si̇ni̇r si̇stemi̇ni̇n oksi̇dati̇f hasari ve melatoni̇n tarafindan korunmasi] (2001) Ankara Universitesi Eczacilik Fakultesi Dergisi, 30 (3), pp. 47-62.

 Ates-Alagoz Z, Suzen S. Structure-activity relationships of melatonin analogues. (2001)  Ankara Universitesi Eczacilik Fakultesi Dergisi., 30 (4), 41-52.

 Süzen, S. Investigations on the effect of base and solvents on the elimination of p-toluene sulphonyl group in the synthesis of dehydroalanine (2001) Ankara Universitesi Eczacilik Fakultesi Dergisi, 30 (1), 17-25.

 Suzen, S., Alagoz, Z., Puskullu, M.O. Antioxidant activities of indole and benzimidazole derivatives (2000) Fabad Journal of Pharmaceutical Sciences, 25 (3), 113-119.

 Suzen, S. The characterisation of the carbohydrate moieties of glycoproteins and the role of hydrazinolysis (1999) Fabad Journal of Pharmaceutical Sciences, 24 (4), 233-239.

 Suzen, S. The role of dehydroalanines in enzyme and peptide chemistry (1999) Ankara Universitesi Eczacilik Fakultesi Dergisi, 28 (2), 129-141.

 Suzen, S. Radioprotective agents in the treatment of cancer and the role of amifostine (1999) Ankara Universitesi Eczacilik Fakultesi Dergisi, 28 (2), 117-128.

 Administrative Charges 

EU Educational Programs and Institutional Erasmus Coordinator of Ankara University (2012-  )

International Students Coordinator of Ankara University (2014-  )

Internationalization Coordinator of Ankara University (2014-  )

Departmental Erasmus coordinator of A.U Faculty of Pharmacy (2004-  )

Mevlana Exchange Program Coordinator of Ankara University (2018- )

European Farmacopea expert, Group 10D (Semi synthetic and synthetic compounds) (2011-  )

Member of European University Association, Intuitional Evaluation Program committee of AnkaraUniversity, Faculty of Pharmacy (2004-2005)

Member of Evaluation of Foreign Pharmacy Faculties for Accreditation committee of AnkaraUniversity, Faculty of Pharmacy (2003-2004)

Member of 5th year Education Program Committee of AnkaraUniversity , Faculty Pharmacy (2004)

European Union General Educational Coordinator of AnkaraUniversity, Faculty Pharmacy (2003-2010)

Member of Executive Committee of Turkish Association of Pharmaceutical and Medicinal Chemistry (2002- 2006)

Member of Faculty Council (2006-2008)

Professional English Language coordinator of Pharmacy Faculty

Invited Lectures

Suzen S. Chemistry and Biology of Antioxidants, "Behavior of new indole based compounds against free radicals with chemopreventive activity "Workshop on Bıochemıstry, Physıology And Pharmacology of Oxıdatıve Stress. Sapienza University of Rome (Italy) July 2-4, 2015.

Suzen S. Melatoninebased indole derivatives as potential antioxidants. 8th Antioxidant meeting 12-14 October-2012, Thessaloniki, Greece

Suzen S. "Melatonin and its analogues as Antioxidants" Ankara University, Ankara, ISOPS-10, June 2012, Host: Prof Maksut Coskun

Suzen S. Chemistry and Biology of Antioxidants, "Novel Indole-Based Melatonın Analogues As Free Radıcal Scavengers" Sapienza University, Rome, Italy, 10-12 November 2011, Host: Prof Luciano Saso

Suzen S “The Role of Indole-based Analogs of Melatonin in Oxidative Defense and Scavenging Free Radicals” Universita Degli Studi Di Parma, Research Seminar, May-2008,Parma, Italy Host: Prof Paolo Colombo.

Suzen S “New developments on aldose reductase inhibitors: the role of indole and pyridazine compounds” Welsh School of Pharmacy, Research Seminar Programme 2007-08 Spring Term, 23 Jan 2008,Cardiff, UK,  Host: Dr. Andrew Westwell.

Suzen S “In Vitro Antioxidant Activities of Melatonin Analogue Indole Derivatives” 3rd International Meeting on Medicinal and Pharmaceutical Chemistry IMMPC-3 October 16-21, L-22,  p.34, Antalya – Turkey-2007.

 

Referee of Following Journals

 Journal of Enzyme Inhibition and Medicinal Chemistry (SCI)

Medicinal Chemistry Research (SCI Expanded)

Turkish Journal of Chemistry (SCI Expanded)

Medicinal Chemistry Communications (SCI Expanded)

Molecules (SCI Expanded)

Mini Reviews in Medicinal Chemistry (SCI Expanded)

Medicinal Chemistry (SCI Expanded)

 

Post Doctoral Studies

 Research grand of British Council (September-1997). University of Wales-Swansea, Chemistry Department, UK

Research grand of The Scientific And Technological Research Council of Turkey-Tubitak (June-September-2004). University of Wales-Swansea, Chemistry Department, UK

Supervised Thesis

  Gokce Gurkok: (MSc) Synthesis, identification and evaluation of antioxidant activity of biologically important some new indole derivatives, 2007

Seyhan Sezen Cihaner: Synthesis and Biological Activity Evaluation of Drug Candidate New Indole-Amino Acid Derivatives, 2009

Ayse Didem Yilmaz: (MSc) Synthesis, Structure Elucidation and Activity Evaluation of New Melatonin Analogue Indole Derivatives, 2010

Ayse Didem Yilmaz: (PhD) Synthesis and Biological Activity Evaluation of New Melatonin Analogue Indole Derivatives, 2011

Ayşe Sözen (MSc) Recent developments of Antiepileptic drugs, 2013

Özlem Öztürk: (Master) Synthesis and Evaluation of Biological Activities of Antimicrobial Indole Derivatives, 2014

Özlem Öztürk: (PhD) Synthesis, identification and evaluation of biological activity of some new indole derivatives 2017

Kübra Durgun: (MSc) Synthesis and evaluation of antioxidant and chemopreventative activity of melatonin analogue new indole derivatives 2018)