Surname : TAKAÇ
E-Mail :
Phone Number : 0(312)203 3434
Title : PROF.DR.
Personal Information


Professor : Ankara University, 1998

Assoc.Professor : Ankara University, 1992

Assist. Pofessor : Ankara University, 1988

Research Assistant: Ankara University, 1983


PhD : Ankara University, 1988

MSc : Ankara University, 1983.

BSc : Ankara University, 1981


Ankara University Faculty of Engineering Department of Biomedical Engineering Head (2014+)
Ankara University Faculty of Engineering Executive Board Member (2012-2015)
Ankara University Graduate School of Science and Applied Sciences Institute
Executive Board Member  (2002-2011)
Ankara University Biotechnology Institute Executive Board Member (2003-2008)
Ankara University Biotechnology Institute Asscociate Director (2006-2008)



TUBITAK NATO Science Fellowship Programme, NATO B-2 (UMIST, Manchester, U.K., 1995-1996)

Bioindustries JICA Programme (Nagoya, Japan, 1995)



  1. Değirmenbaşı D, Takaç S., 2018. Olive Mill Wastewater As a Natural Source for Superoxide Dismutase and Catalase Enzymes by Rhodotorula glutinis, CLEAN-Soil, Air, Water, doi: 10.1002/clen.201700228.
  2. Ülger C, Takaç S., 2017Kinetics of Lipase-Catalysed Methyl Gallate Production in the Presence of Deep Eutectic Solvent. Biocatalysis and Biotransformation, 35(6) 407-416. doi:10.1080/10242422.2017.1359573.
  3. Ünlü ,A. E., Takaç, S. 2017, Improvement of Superoxide Dismutase Activity using Experimental Design And Radical Promoters. Biotechnology and Biotechnological Equipment, 31(5) 1046–1054 doi: 10.1080/13102818.2017.1353923 
  4. Karakaya, A., Kenar, A., Laleli, Y. Takaç S., 2017. Novel Two-Step Process to Co-valorize Antioxidant Rich By-products of Olive and Grape Processing Industries, Waste and Biomass Valorization, 8(3)829-837.
  5. Karakaya,A., Laleli, Yahya, Takaç, S., 2016. Industry–university partnership for the simultaneous biotechnological degradation and value enhancement of olive mill wastewater, OLIVAE, 123, 48-51. 
  6. Bozkoyunlu, G, Takaç S., 2014. Parameters and kinetics of olive  mill wastewater dephenolisation by immobilised Rhodotorula glutinis cells, Environmental Technology, 35(24):3074-81.
  7. Karakaya, A., Bozkoyunlu, G., Laleli,Y., Takaç,S., 2014. Development of pH-adjustment based operational strategy to increase total phenol removal rate in biodegradation of olive mill wastewater by Rhodotorula glutinisDesalination and Water Treatment, 52 (37-39): 7277-7281
  8. Karakaya, A., Laleli,Y., Takaç,S., 2012. Development of process conditions for biodegradation of raw olive mill wastewater by Rhodotorula glutinis, International Biodeterioration & Biodegradation, 75, 75- 82.
  9. Ünlü,A.E., Takaç,S., 2012. Investigation of the Simultaneous Production of Superoxidedismutase and Catalase Enzymes from Rhodotorula glutinis under Different Culture Conditions, Artificial Cells, Blood Substitutes, and Biotechnology, 40 (5,) 338-344.
  10. Tekin,N., Coleri Cihan A., Takac,S., Yagci, C., Tunc,K., Cokmus,C., 2012. Characterization of an extremely stable alkaline protease from Bacillus cohnii APT5, Turkish Journal of Biology, 36, 430-44.
  11. Arslan, Y., Takaç, S., Eken-Saraçoğlu, N., 2012. Kinetic Study of Hemicellulosic Sugar Production from Hazelnut Shells, Chemical Engineering Journal, 185– 186, 23– 28.
  12. Takaç,S., Ünlü,A.E., Erdem,B., 2010. Oxygen Transfer Strategy Modulates the Productions of Lipase and Esterase Enzymes by Candida rugosa, Journal of Molecular Catalysis B: Ezymatic, 64, 150–154.
  13. Takaç, S., Şengel, B.Ş., 2010. Extracellular Lipolytic Enzyme Activity of a Newly Isolated Debaryomyces hansenii, Preparative Biochemistry & Biotechnology, 40, 28-37.
  14. Takaç, S., Karakaya, A., 2009. Recovery of Phenolic Antioxidants from Olive Mill Wastewater, Recent Patents on Chemical Engineering, 2(3) 230-237.
  15. Takaç,S., Erdem,B., Ünlü,A.E., 2009. Impact of Inoculation Strategy on the Progress of Candida rugosa Cultivation, Artificial Cells, Blood Substitutes, and Biotechnology, 37 (3) 130-137.
  16. Takaç,S., Erdem,B., 2009. Media Formulation Using Complex Organic Nutrients for the Improved Activity, Productivity and Yield of Candida rugosa Lipase and Esterase Enzymes, Preparative Biochemistry & Biotechnology, 39 (3) 323-341.
  17. Takaç,S., Ünlü,A.E., 2009. Effects of Alcohol and Buffer Treatments on the Activity and Enantioselectivity of Candida rugosa Lipase, Preparative Biochemistry & Biotechnology, 39 (2) 124-141.
  18. Takaç,S., Marul,B., 2008. Effects of Lipidic Carbon Sources on the Extracellular Lipolytic Activity of a Newly Isolated Bacillus subtilis, Journal of Industrial Microbiology & Biotechnology, 35: 1019-1025.
  19. Salgın,S., Takaç,S., 2007. Effects of Additives on the Activity and Enantioselectivity of Candida rugosa Lipase in Biphasic Medium, Chemical Engineering & Technology, 30 (12), 1739-1743.
  20. Ertuğrul,S., Dönmez,G., Takaç,S., 2007. Isolation of Lipase Producing Bacterial Strain from Olive Mill Wastewater and Improving its Enzyme Activity, Journal of Hazardous Materials, 149, 720-724.
  21. Salgın,U., Salgın,S., Takaç,S., 2007. The Enantioselective Hydrolysis of Racemic Naproxen Methyl Ester in Supercritical CO2 using Candida rugosa Lipase, Journal of Supercritical Fluids, 43(2), 310-316.
  22. Takaç,S., Mutlu,D., 2007. Biphasic Medium Conditions for the Enantioselective Production of Naproxen by Candida rugosa Lipase, Applied Biochemistry and Biotechnology, 141 (1), 15-26.
  23. Takaç,S., Bakkal,M., 2007. Impressive Effect of Immobilization Conditions on the Catalytic Activity and Enantioselectivity of Candida rugosa Lipase Toward S-Naproxen Production, Process Biochemistry, 42, 1021-1027.



Undergraduate: Fluid Mechanics, Heat Transfer, Enzyme Engineering,  Research Techniquies

Graduate: Biochemical Reaction Engineering


Green Processes: Production / Separation 

Microbial productions (lipid, enzyme, antioxidant) 

Enzymatic / catalytic reactions (esterification, transesterification, oxidation)

Green solvents

Chemical/biochemical reaction kinetics

Valorization of biomass


PROJECTS (2007 +)


 1.      Microbial Lipid Production from Olive Mill Wastewater in a Bioreactor System, BAP, 17H0443001 (2017-2018)

2.      Use of Alternative Solvents in the Production of Polymeric Biomaterials, BAP, 17Ö0443002 (2017-2018)

3.      Ethyl Lactate Production in a Novel and Environmentally Friendly Extractive Reaction Process, TÜBİTAK, 117M884 (2017-2018)


  1. Food Waste Valorization for sustaniable chemicals, materials and fuels (EUBis), COST Action TD1203 (2013-2016).
  2. Production of Value Added Biomolecules from Olive Mill Wastewater TÜBİTAK 113M589 (2013-2015)
  3. Medium design for the production of antioxidant enzymes production from olive mill wastewater BAP 14H044302 (2014-15)
  4. Utilisation of Biomass for Sustainable Fuels & Chemicals (UBIOCHEM), COST Action MC0903 (2010-2013)
  5.  Immobilization of Rhodotorula glutinis for Bioremediation of Olive Mill Wastewater, BAP 12B43433001 (2012-13)
  6. Development of an Integrated Process for Olive Mill Wastewater to Enrich its Phenolic Compoundsby Successive Homogenization-Extraction Process and to Facilitate its BioremediationTUBITAK, MAG 111M441 (2011-2012)
  7. Process Biodevelopment for Remediation of Olive Mill Wastewater and Utilization in Antioxidant Production, TUBITAK MAG 109M290 (2009-2011)
  8. Comparison of Debaryomyces hansenii Proteins Under Different Stress Conditions BAP 09B4343011 (2009-2010)
  9.  The Identification of Screened Microorganisms from Several Sources by Genetic Techniques and Purification of Produced Enzymes,BAP 2007-07-45-004HPD (2007-2008)