DR.ÖĞR.ÜYESİ FAHRİYE ULYA BADILLI    
Name : FAHRİYE ULYA
Surname : BADILLI
E-Mail : unuman@pharmacy.ankara.edu.tr
Phone Number : 0 312 203 31 52
Title : DR.ÖĞR.ÜYESİ
Unit : FACULTY OF PHARMACY
Department :
Personal Information

Education

 

2003 - 2009                : Ankara University Faculty of Pharmacy 

                                     Department of Pharmaceutical Technology

                                     Pharmaceutical Technology Programme-Ph D Education 

2000 - 2003                Ankara University Faculty of Pharmacy

                                     Department of Pharmaceutical Technology                   

                                     Cosmetology Programme-Master of Science Education 

1995 – 1999               :  Ankara University Faculty of Pharmacy 

                                                  Undergraduate Education 

 

 

Publications 

  • NUMANOĞLU, U., TARIMCI, N. (2006). Cyclodextrins and their usage in cosmetics. Türkiye Klinikleri J Int Med Sci, 2(17): 40-46.
  • NUMANOĞLU, U., TARIMCI, N. (2006). Characterization of solid lipid nanoparticles (SLNTM) and their pharmaceutical and cosmetic applications.  J Fac Pharm Ankara, 35(3): 211-235.
  • NUMANOĞLU, U., ŞEN, T., TARIMCI, N., KARTAL, M., KOO, O.M.Y., ÖNYÜKSEL, H. (2007). Use of cyclodextrins as a cosmetic delivery system for fragrance materials: linalool and benzyl acetate. AAPS PharmSciTech, 8(4), Article 85: E1-E9.  
  • BADILLI (NUMANOĞLU), F.U., ŞEN, T., TARIMCI, N. (2009).  The effect of homogenization speed on the in vitro characteristics of the PLGA microparticles prepared using O/W emulsion – solvent evaporation method. European Journal of Pharmaceutical Sciences, 38 (1) Suppl: 146-147. 
  • BADILLI, U., TARIMCI, N. (2009). Applications of electrospraying method in nanotechnology.  J Fac Pharm Ankara, 38(2): 117-135.

  • ŞENGEL-TÜRK, C.T., SEZGİN-BAYINDIR, Z., BADILLI, U. (2009). Preparation of polymeric nanoparticles using different stabilizing agents. J Fac Pharm Ankara, 38(4): 257-268.

  • BADILLI, U., ŞEN, T., TARIMCI, N. (2011). Microparticulate based topical delivery system of clobetasol propionate. AAPS PharmSciTech, 12(3): 949-957. 
  • BADILLI, U., AMASYA, G., OZKAN, S., TARIMCI, N. (2013). Simultaneous determination of clobetasol propionate and calcipotriol in a novel fixed dose emulgel formulation by LC-UV. Chromatographia, 76: 133-140.  
  • BADILLI, U., AMASYA, G., ŞEN, T., TARIMCI, N. (2013). Topical emulgel formulation containing inclusion complex of calcipotriol with cyclodextrin. Journal of Inclusion Phenomena and Macrocyclic Chemistry, DOI: 10.1007/s10847-013-0293-2.
    • TESTA, G., GAMBA, P., BADILLI, U., GARGIULO, S., MAINA, M., GUINA, T., CALFAPIETRA, S., BIASI, F., CAVALLI, R., POLI, G., LEONARDUZZI, G. (2014). Loading into nanoparticles improves quercetin’s efficacy in preventing neuroinflammation induced by oxysterols. PLoS ONE, 9(5): e96795. doi:10.1371/journal.pone.0096795.
    • BADILLI, U., SENGEL-TURK, C.T., ONAY-BESIKCI, A., TARIMCI, N. (2015). Development of etofenamate-loaded semisolid SLN dispersions and evaluation of anti-inflammatory activity for topical application. Current Drug Delivery, 12(2): 200-209.
    • BADILLI, U., ONAY-BESIKCI, A., AMASYA, G., SEN, T., TARIMCI, N. (2015). Calcipotriol-Captisol Inclusion Complex And Corticosteroid In A Novel Fixed Dose Combination: Evaluation On Human Epidermal Keratinocyte Cells. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 83: 363-368. DOI: 10.1007/s10847-015-0572-1.
    • AMASYA, G., BADILLI, U., AKSU, B., TARIMCI, N. (2016). Quality by design case study 1: Design of 5-fluorouracil loaded lipid nanoparticles by the W/O/W double emulsion – solvent evaporation method. European Journal of Pharmaceutical Sciences, 84: 92-102. 
    • AMASYA, G., SANDRI, G., ONAY-BESIKCI, A., BADILLI, U., CARAMELLA, C., BONFERONI, M.C., TARIMCI, N. (2016). Skin Localization of Lipid Nanoparticles (SLN/NLC): Focusing the Influence of Formulation Parameters. Current Drug Delivery, 13(7): 1100-1110.
    • GUMUSTAS, M., TURK, C.T., BADILLI, U., AMASYA, G., OZKAN, S., TARIMCI, N. (2017). Optimization Of Stability Indicating LC Method For The Sensitive In Vitro Determination From Solid Lipid Nanoparticles And Ex Vivo Analysis From Rat Skin Of Etofenamate. Current Pharmaceutical Analysis, 13(1): 63-71.
    • BADILLI, U., TURK, C.T., AMASYA, G., TARIMCI, N. (2017). Novel drug delivery system for dermal uptake of etofenamate: semisolid SLN dispersion. Current Drug Delivery, 14(3): 386 – 393.
    • BADILLI, U. Peptit / Protein İçeren Ürünler, Türkiye Klinikleri J Cosm Dermatol – Special Topics, 10(1): 39-44, 2017.
    • TARIMCI, N., BADILLI, U.  Deri Yaşlanmasında Derinin Rengi ve Renk Açıcı Ürünler, Türkiye Klinikleri J Cosm Dermatol – Special Topics, 10(1): 45-51, 2017. 
    • AYDIN, E., BADILLI, U., ONAY-BESIKCI, A., TARIMCI, N. (2018). Thermosensitive in situ gel formulation containing PLGA nanoparticles of flurbiprofen for ocular delivery. Acta Poloniae Pharmaceutica - Drug Research, 75(1):  141- 153. 

    Kitaplar ve Kitap Bölümleri

    TARIMCI, N., BADILLI, U. (2014). Nanotaşıyıcıların kozmetik uygulamaları. In: Nanofarmasötikler ve Uygulamaları. Ed: A. ZIRH-GÜRSOY, Kontrollü Salım Sistemleri Derneği Yayını No:3, İstanbul, Bölüm 25.

    TARIMCI, N.; SENGEL-TURK, C.T.; BADILLI, U.  (2015). A Novel Approach for Topical Delivery of SLNs: Semisolid SLNs, LAP Lambert Academic Publishing, Saarbrücken - Germany. 


    BADILLI, U., TARIMCI, N. (2016). Dermakozmetik / Kozmesötik Etkin Maddeler –I. In: Dermakozmetik Kozmesötik Madde ve Ürünler. Ed: E. Y. YAZAN, Nobel Tıp Kitabevleri, İstanbul, Bölüm 3.

    Bildiriler

     

    • NUMANOĞLU, U., KARTAL, M., ŞEN, T., TARIMCI, N., ÖNYÜKSEL, H. “Improving solubility of fragrance materials by cyclodextrin complexation I: Linalool” European Conference on Drug Delivery and Pharmaceutical Technology, 10-12 May 2004,  Sevilla-SPAIN, p:92.
    • NUMANOĞLU, U., ŞEN, T., TARIMCI, N., ÖNYÜKSEL, H., KARTAL, M., KOO, O. “Improving solubility of fragrance materials by cyclodextrin complexation II: Benzyl acetate” 12th International Pharmaceutical Technology Symposium (IPTS-2004), 12-15 Sept 2004,  İstanbul-TURKEY, p:235-236.
    • NUMANOĞLU, U., ŞEN, T., TARIMCI, N. “Controlled release of fragrance materials by complexation with cyclodextrins ” 15th International Symposium on Microencapsulation, 18-21 Sept 2005,  Parma-ITALY, p:271-272.
    • SEZGİN, Z., NUMANOĞLU, U., DEVRİM, B., ŞENGEL-TÜRK, C.T., KARATAŞ, A. “Preparation and in vitro characterization of indomethacin loaded PLGA microspheres” 13th International Pharmaceutical Technology Symposium (IPTS-2006), 10-13 Sept 2006,  Antalya-TURKEY, p:119-120. 
    • NUMANOĞLU, U., ŞEN, T., TARIMCI, N. “Preparation and in vitro evaluation of clobetasol propionate loaded PLGA micropartricles as topical drug delivery system for treatment of psoriasis vulgaris” World Congress of Pharmacy and Pharmaceutical Sciences - 68th International Congress of FIP, 29 Aug-4 Sept 2008, Basel-SWITZERLAND, p:182. 
    • BADILLI (NUMANOĞLU), F.U., ŞEN, T., TARIMCI, N. “Clobetasol propionate loaded PLGA microparticles for topical drug delivery: the effect of the emulsifier ratio” 36th CRS Annual Meeting & Exposition, 18-22 July 2009, Cophenhagen-DENMARK, Poster No: 1024.
    • BADILLI (NUMANOĞLU), F.U., ŞEN, T., TARIMCI, N. “The effect of homogenization speed on the in vitro characteristics of the PLGA microparticles prepared using O/W emulsion – solvent evaporation method” 3rd BBBB International Conference on Pharmaceutical Sciences, 26-28 October 2009, Antalya-TURKEY, p: 146-147.
    • BADILLI, U., ŞEN, T., TARIMCI, N. “A new topical delivery system of clobetasol propionate for the treatment of psoriasis” FIP Pharmaceutical Sciences World Congress in association with the AAPS Annual Meeting and Exposition, 14-18 November 2010, New Orleans, Louisiana-USA, Final Program Book, W4127, p: 175.
    • BADILLI, U., ŞEN, T., TARIMCI, N. “Calcipotriol entrapped cyclodextrin carrier systems for improving the solubility” 38th Annual Meeting & Exposition of the Controlled Release Society, 30 July-3 August 2011, National Harbor, Maryland-USA, Poster No: 473.
    • BADILLI, U., ŞEN, T., TARIMCI, N. “Development of a topical delivery system containing inclusion complex of calcipotriol” 18th International Symposium on Microencapsulation, 12-14 September 2011, Antalya-TURKEY, p: 188-190.
    • ŞENGEL TÜRK, C.T., SEZGİN BAYINDIR, Z., BADILLI, U. “Effect of stabilizing agents on the characteristics of PLGA nanoparticles” 10th International Symposium on Pharmaceutical Sciences (ISOPS-10), 26-29 June 2012, Ankara-TURKEY, p: 312.
    • KOPARAN, F.B., BADILLI, U., TARIMCI, N. “Increasing the solubility of flurbiprofen with cyclodextrins” 10th International Symposium on Pharmaceutical Sciences (ISOPS-10), 26-29 June 2012, Ankara-TURKEY, p: 315. 
    • AYDIN, E., BADILLI, U., TARIMCI, N. “Development of ocular nanoparticles containing a nonsteroidal anti-inflammatory drug: flurbiprofen” 16th International Pharmaceutical Technology Symposium (IPTS-2012), 10-12 September 2012, Antalya-TURKEY, p: 173-174.
    • BADILLI, U., AMASYA, G., ÖZKAN, S., TARIMCI, N. “High performance liquid chromatographic determination of clobetasol propionate and calcipotriol in a fixed dose combination formulation” 16th International Pharmaceutical Technology Symposium (IPTS-2012), 10-12 September 2012, Antalya-TURKEY, p: 175-176.
    • BADILLI, U., AMASYA, G., ŞEN, T., TARIMCI, N. “Solubility enhancement of calcipotriol with Captisol® ” The 9th Central European Symposium on Pharmaceutical Technology (CESPT 2012), 20-22 September 2012, Dubrovnik-CROATIA, p: 142.
    • AMASYA, G., BADILLI, U., TARIMCI, N. “Solid lipid nanoparticles of 5-fluorouracil for skin cancer” 3rd Conference on Innovation in Drug Delivery: Advances in Local Drug Delivery, 22-25 September 2013, Pisa-ITALY, p: 151.
    • AYDIN, E., BADILLI, U., TARIMCI, N. “Flurbiprofen loaded PLGA nanoparticles as ocular drug delivery system” 2013 AAPS Annual Meeting and Exposition, 10-14 November 2013, San Antonio-USA.
    •  YÜZÜKIRMIZI, S., BADILLI, U., TARIMCI, N. “Vaginal drug delivery of clotrimazole loaded PLGA nanoparticles” 2013 AAPS Annual Meeting and Exposition, 10-14 November 2013, San Antonio-USA.
    • AYDIN, E., BEŞİKCİ, A., BADILLI, U., TARIMCI, N. “Inhibition of cyclooxygenase-1 enzyme by flurbiprofen loaded ophthalmic nanoparticles” Pharmaceutical Sciences World Congress (PSWC 2014), 13-16 April 2014, Melbourne-AUSTRALIA.
    • AYDIN, E., BADILLI, U., TARIMCI, N. “Thermosensitive in-situ gel formulation of flurbiprofen nanoparticles as ocular drug delivery system” 17th International Pharmaceutical Technology Symposium (IPTS-2014), 8-10 September 2014, Antalya-TURKEY, p: 189-191.
    • BADILLI, U., ONAY BESİKCİ, A., AMASYA, G., ŞEN, T., TARIMCI, N. “In vitro antipsoriatic activity of fixed-dose combination of calcipotriol and clobetasol propionate” 2014 AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego-USA.
    • AMASYA, G., SANDRI, G., ONAY BESİKCİ, A., BADILLI, U., CARAMELLA, C., BONFERONI, C., TARIMCI, N. “Qualitative and quantitative skin effects of lipid nanoparticles” 2014 AAPS Annual Meeting and Exposition, 2-6 November 2014, San Diego-USA.
    • ŞEN, T., AMASYA, G., BADILLI, U., TARIMCI, N. “Preparation and evaluation of NLC contained Argan oil and Inutec SP1” Nanobiotechnology Days, 14-15 May 2015, İstanbul-TURKEY.
    • BADILLI, U., SENGEL-TURK, C.T., AMASYA, G., TARIMCI, N. “Occlusive and mechanical characteristics of etofenamate encapsulated semisolid SLN formulations” 11th International Symposium on Pharmaceutical Sciences (ISOPS-11), 09-12 June 2015, Ankara-TURKEY, p: 177-178.
    • ŞEN, T., BADILLI, U., İNAL, Ö., AMASYA, G., ÖZTÜRK, Ç., ÇAKIR, K., TARIMCI, N. “Availability of argan oil as liquid lipid in NLC formulations to improve skin hydration” 11th International Symposium on Pharmaceutical Sciences (ISOPS-11), 09-12 June 2015, Ankara-TURKEY, p: 176-177.
    • AMASYA, G., GUMUSTAS, M., SENGEL-TURK, C.T., BADILLI, U., OZKAN, S.A., TARIMCI, N. “Optimization of Sensitive and Selective RP-LC Method For The Determination Of Etofenamate From Rat Skin” 18th The European Conference on Analytical Chemistry, Euroanalysis 2015, 6–10 September 2015, Bordoeux - FRANCE.
    • AMASYA, G., AKSU, B., BADILLI, U., TARIMCI, N. “Optimization of 5-Fluorouracil Loaded Solid Lipid Nanoparticle (SLN) Formulations Based on Artificial Neural Network” 6th BBBB Conference on Pharmaceutical Sciences ‘Strategies To Improve The Quality And Performance Of Modern Drug Delivery Systems’, 10-12 September 2015, Helsinki - FINLAND (Oral Presentation – Buket AKSU).
    • AMASYA, G., BADILLI, U., TARIMCI, N. "The Combination of the Best Fitted Emulsification Method For Producing SLN with the w/o/w Double Emulsion - Solvent Evaporation Method” 75th FIP World Congress of Pharmacy and Pharmaceutical Sciences 2015, 29 September - 3 October 2015, Düsseldorf - GERMANY.
    • AMASYA, G., BADILLI, U., AKSU, B., TARIMCI, N. “Evaluation of 5-Fluorouracil Loaded Lipid Nanoparticles for Skin Cancer: A Quality by Design Approach by Using Artificial Neural Network Program” AAPS Annual Meeting and  Exposition, 25-29 November, 2015, Orlando – FLA - USA.
    • BADILLI, U., SENGEL-TURK, C.T., AMASYA, G., TARIMCI, N. “Dermal behaviour of semisolid SLN dispersions of etofenamate” 1st International Gazi Pharma Symposium Series (GPSS 2015), 12-15 November 2015, Antalya-TURKEY, p: 78
    • AMASYA, G., BADILLI, U., ONAY-BESİKCİ, A., TARIMCI, N. “Lipid nanoparticle based Carbopol gel for topical chemotherapy of  5-Fluorouracil” 15th Annual Meeting of  Skin Forum, 21-22 June 2016, London - ENGLAND.
    • AMASYA, G., BADILLI, U., AKSU, B., TARIMCI, N. “Computational approaches to estimate NLC formulation: artificial neural network” 18th International Pharmaceutical Technology Symposium (IPTS-2016), 18 – 21 September 2016, Antalya – TURKEY, s:156-158.
    • AMASYA, G., AKSU, B., BADILLI, U., TARIMCI, N. “An implementation of artificial neural network: physicochemical characterization of lipid nanoparticles” 4th Conference on Innovation in Drug Delivery: Site-Specific Drug Delivery, 25-28 September 2016, Antibes-Juan-les-Pins – FRANCE, s: 120.
    • AMASYA, G., BADILLI, U., AKSU, B., TARIMCI, N. “QbD guided early pharmaceutical development study: Production of lipid nanoparticles by high pressure homogenization” 2nd European Conference on Pharmaceutics: Novel Dosage Forms and Innovative Technologies, 3-4 April 2017, Krakow-POLAND, Poster no: 115.
    • AMASYA, G., AKSU, B., BADILLI, U., TARIMCI, N. “Artificial intelligence based optimization of lipid nanoparticles” 6th FIP Pharmaceutical Sciences World Congress (PSWC 2017), 21-24 May 2017, Stockholm-SWEDEN.
    • AMASYA, G., GUMUSTAS, M., BADILLI, U., TARIMCI, N. OZKAN, SA.  “Optimization and Validation of HPLC Method for the Determination of 5-Fluorouracil from Lipid Nanoparticles and Rat Skin Extracts” XXVIII International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2017), 2-5 July 2017, Madrid-SPAIN, s:149.
    • AMASYA, G., BADILLI, U., AKSU, B., TARIMCI, N. “QbD Implementation for Obtaining 5Fluorouracil Loaded NLC Formulation” 2017 Controlled Release Society Annual Meeting, 16-19 July 2017, Boston-USA.
    • AMASYA, G., SENGEL-TURK, C.T., BADILLI, U., TARIMCI, N. “Design and Optimization of Fluticasone Propionate Loaded Solid Lipid Nanoparticles by 32 Factorial Design” 2nd International Gazi Pharma Symposium Series (GPSS 2017), 11-13 October 2017, Ankara-TURKEY, P43.
    • GUMUSTAS, M., AMASYA, G., BADILLI, U., OZKAN, S.A., TARIMCI, N. “Validation of a HILIC method for the analysis of 5-fluorouracil loaded lipid nanoparticles and application to in vitro and ex vivo tests” EastWest Chemistry Conference, 12-14 October 2017, Skopje-MACEDONIA, S012  (Oral presentation – Mehmet GÜMÜŞTAŞ)
    • GUMUSTAS, M., AMASYA, G., SENGEL-TURK, C.T., BADILLI, U., TARIMCI, N., OZKAN, S.A. “Validation of HPLC Methods for the analysis of nanoparticle based drug delivery systems” 8th Annual Symposium on Physical and Analytical Chemistry, 28-29 December 2017, Tiflis-GÜRCİSTAN (Tbilisi-GEORGIA) (Oral presentation – Mehmet GÜMÜŞTAŞ)

Proceedings 

  • NUMANOĞLU, U., KARTAL, M., ŞEN, T., TARIMCI, N., ÖNYÜKSEL, H. “Improving solubility of fragrance materials by cyclodextrin complexation I: Linalool” European Conference on Drug Delivery and Pharmaceutical Technology, 10-12 May 2004,  Sevilla-SPAIN, p:92.
  • NUMANOĞLU, U., ŞEN, T., TARIMCI, N., ÖNYÜKSEL, H., KARTAL, M., KOO, O. “Improving solubility of fragrance materials by cyclodextrin complexation II: Benzyl acetate” 12th International Pharmaceutical Technology Symposium (IPTS-2004), 12-15 Sept 2004,  İstanbul-TURKEY, p:235-236.
  • NUMANOĞLU, U., ŞEN, T., TARIMCI, N. “Controlled release of fragrance materials by complexation with cyclodextrins ” 15th International Symposium on Microencapsulation, 18-21 Sept 2005,  Parma-ITALY, p:271-272.
  • SEZGİN, Z., NUMANOĞLU, U., DEVRİM, B., ŞENGEL-TÜRK, C.T., KARATAŞ, A. “Preparation and in vitro characterization of indomethacin loaded PLGA microspheres” 13th International Pharmaceutical Technology Symposium (IPTS-2006), 10-13 Sept 2006,  Antalya-TURKEY, p:119-120. 
  • NUMANOĞLU, U., ŞEN, T., TARIMCI, N. “Preparation and in vitro evaluation of clobetasol propionate loaded PLGA micropartricles as topical drug delivery system for treatment of psoriasis vulgaris” World Congress of Pharmacy and Pharmaceutical Sciences - 68th International Congress of FIP, 29 Aug-4 Sept 2008, Basel-SWITZERLAND, p:182. 
  • BADILLI (NUMANOĞLU), F.U., ŞEN, T., TARIMCI, N. “Clobetasol propionate loaded PLGA microparticles for topical drug delivery: the effect of the emulsifier ratio” 36th CRS Annual Meeting & Exposition, 18-22 July 2009, Cophenhagen-DENMARK, Poster No: 1024.
  • BADILLI (NUMANOĞLU), F.U., ŞEN, T., TARIMCI, N. “The effect of homogenization speed on the in vitro characteristics of the PLGA microparticles prepared using O/W emulsion – solvent evaporation method” 3rd BBBB International Conference on Pharmaceutical Sciences, 26-28 October 2009, Antalya-TURKEY, p: 146-147.
  • BADILLI, U., ŞEN, T., TARIMCI, N. “A new topical delivery system of clobetasol propionate for the treatment of psoriasis” FIP Pharmaceutical Sciences World Congress in association with the AAPS Annual Meeting and Exposition, 14-18 November 2010, New Orleans, Louisiana-USA, Final Program Book, W4127, p: 175.
  • BADILLI, U., ŞEN, T., TARIMCI, N. “Calcipotriol entrapped cyclodextrin carrier systems for improving the solubility” 38th Annual Meeting & Exposition of the Controlled Release Society, 30 July-3 August 2011, National Harbor, Maryland-USA, Poster No: 473.
  • BADILLI, U., ŞEN, T., TARIMCI, N. “Development of a topical delivery system containing inclusion complex of calcipotriol” 18th International Symposium on Microencapsulation, 12-14 September 2011, Antalya-TURKEY, p: 188-190.
  • ŞENGEL TÜRK, C.T., SEZGİN BAYINDIR, Z., BADILLI, U. “Effect of stabilizing agents on the characteristics of PLGA nanoparticles” 10th International Symposium on Pharmaceutical Sciences (ISOPS-10), 26-29 June 2012, Ankara-TURKEY, p: 312.
  • KOPARAN, F.B., BADILLI, U., TARIMCI, N. “Increasing the solubility of flurbiprofen with cyclodextrins” 10th International Symposium on Pharmaceutical Sciences (ISOPS-10), 26-29 June 2012, Ankara-TURKEY, p: 315. 
  • AYDIN, E., BADILLI, U., TARIMCI, N. “Development of ocular nanoparticles containing a nonsteroidal anti-inflammatory drug: flurbiprofen” 16th International Pharmaceutical Technology Symposium (IPTS-2012), 10-12 September 2012, Antalya-TURKEY, p: 173-174.
  • BADILLI, U., AMASYA, G., ÖZKAN, S., TARIMCI, N. “High performance liquid chromatographic determination of clobetasol propionate and calcipotriol in a fixed dose combination formulation” 16th International Pharmaceutical Technology Symposium (IPTS-2012), 10-12 September 2012, Antalya-TURKEY, p: 175-176.
  • BADILLI, U., AMASYA, G., ŞEN, T., TARIMCI, N. “Solubility enhancement of calcipotriol with Captisol® ” The 9th Central European Symposium on Pharmaceutical Technology (CESPT 2012), 20-22 September 2012, Dubrovnik-CROATIA, p: 142.